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TBXA2R elisa kit :: Human thromboxane A2 receptor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS921337
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

thromboxane A2 receptor (TBXA2R), ELISA Kit

★Popular Item★
 Also Known As   

Human Thromboxane A2 receptor, TBXA2R ELISA Kit

 Product Synonym Names    Human Thromboxane A2 receptor (TBXA2R) ELISA kit; TXA2-R; prostanoid TP receptor; thromboxane A2 receptor
 Product Gene Name   

TBXA2R elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS921337 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for Q95125
 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human TBXA2R. No significant cross-reactivity or interference between Human TBXA2R and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    25 pg/ml-1600 pg/ml
 Sensitivity    6.25 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TBXA2R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TBXA2R purchase    MBS921337 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the thromboxane A2 receptor (TBXA2R) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 25 pg/ml-1600 pg/ml in biological research samples containing TBXA2R, with an estimated sensitivity of 6.25 pg/ml. The ELISA analytical biochemical technique of the MBS921337 kit is based on TBXA2R antibody-TBXA2R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TBXA2R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TBXA2R. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TBXA2R elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TBXA2R has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TBXA2R present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TBXA2R is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TBXA2R bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of TBXA2R elisa kit    TBXA2R elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS921337. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TBXA2R. It may not necessarily be applicable to this product.
 NCBI GI #    269315860
 NCBI GeneID    538783
 NCBI Accession #    NP_001161391.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001167919.1 [Other Products]
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 UniProt Primary Accession #    Q95125 [Other Products]
 UniProt Secondary Accession #    Q95124 [Other Products]
 UniProt Related Accession #    Q95125 [Other Products]
 Molecular Weight    37,841 Da
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 NCBI Official Full Name    thromboxane A2 receptor
 NCBI Official Synonym Full Names    thromboxane A2 receptor
 NCBI Official Symbol    TBXA2R [Similar Products]
 NCBI Protein Information    thromboxane A2 receptor; TXA2-R; prostanoid TP receptor
 UniProt Protein Name    Thromboxane A2 receptor
 UniProt Synonym Protein Names   
Prostanoid TP receptor
 Protein Family    Thromboxane A2 receptor
 UniProt Gene Name    TBXA2R [Similar Products]
 UniProt Synonym Gene Names    TXA2-R [Similar Products]
 UniProt Entry Name    TA2R_BOVIN
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 UniProt Comments for TBXA2R    Function: Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C and adenylyl cyclase.
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 Research Articles on TBXA2R    1. Thromboxane A2 receptor activation via PKC-zeta-mediated NAD(P)H oxidase activation increases superoxide and peroxynitrite, resulting in eNOS uncoupling in endothelial cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TBXA2R elisa kitDiseases associated with TBXA2R elisa kit
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (12/13) Signalling Events Pathway antibodies  G Alpha (12/13) Signalling Events Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Disease Name  Pubmed Publications
 Respiratory Hypersensitivity Antibodies  >16 publications with TBXA2R and Respiratory Hypersensitivity
 Lung Diseases Antibodies  >15 publications with TBXA2R and Lung Diseases
 Inflammation Antibodies  >5 publications with TBXA2R and Inflammation
 Drug Hypersensitivity Antibodies  >5 publications with TBXA2R and Drug Hypersensitivity
 Asthma, Aspirin-Induced Antibodies  >5 publications with TBXA2R and Asthma, Aspirin-Induced
 Myocardial Infarction Antibodies  >3 publications with TBXA2R and Myocardial Infarction
 Urticaria Antibodies  >3 publications with TBXA2R and Urticaria
 Cardiovascular Diseases Antibodies  >3 publications with TBXA2R and Cardiovascular Diseases
 Rhinitis Antibodies  >3 publications with TBXA2R and Rhinitis
 Neoplasms Antibodies  >2 publications with TBXA2R and Neoplasms
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