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TSHR elisa kit :: Human thyroid stimulating hormone receptor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS703110
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

thyroid stimulating hormone receptor (TSHR), ELISA Kit

★Popular Item★
 Also Known As   

Human Thyroid Stimulatin Hormone Receptor, TSHR ELISA Kit

 Product Synonym Names    Human Thyroid Stimulatin Hormone Receptor (TSHR) ELISA Kit; CHNG1; LGR3; MGC75129; hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor; isoform 2; thyrotropin receptor; thyrotropin receptor-I; hTSHR-I; thyroid stimulating hormone receptor
 Product Gene Name   

TSHR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS703110 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for Q27987
 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human TSHR. No significant cross-reactivity or interference between human TSHR and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    0.5 ng/ml - 20 ng/ml.
 Sensitivity    The minimum detectable dose of human TSHR is typically less than 0.25 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest human TSHR concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TSHR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TSHR purchase    MBS703110 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the thyroid stimulating hormone receptor (TSHR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.5 ng/ml - 20 ng/ml in biological research samples containing TSHR, with an estimated sensitivity of The minimum detectable dose of human TSHR is typically less than 0.25 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest human TSHR concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. The ELISA analytical biochemical technique of the MBS703110 kit is based on TSHR antibody-TSHR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TSHR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TSHR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TSHR elisa kit

   Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TSHR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells with a Horseradish Peroxidase (HRP) conjugated antibody specific for TSHR. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TSHR bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of TSHR elisa kit    TSHR elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS703110. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TSHR. It may not necessarily be applicable to this product.
 NCBI GI #    27806373
 NCBI GeneID    281553
 NCBI Accession #    NP_776631.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_174206.3 [Other Products]
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 UniProt Primary Accession #    Q27987 [Other Products]
 UniProt Secondary Accession #    Q27986 [Other Products]
 UniProt Related Accession #    Q27987 [Other Products]
 Molecular Weight    86,431 Da
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 NCBI Official Full Name    thyrotropin receptor
 NCBI Official Synonym Full Names    thyroid stimulating hormone receptor<
 NCBI Official Symbol    TSHR [Similar Products]
 NCBI Protein Information    thyrotropin receptor; TSH-R; thyroid-stimulating hormone receptor
 UniProt Protein Name    Thyrotropin receptor
 UniProt Synonym Protein Names   
Thyroid-stimulating hormone receptor; TSH-R
 Protein Family    Thyrotropin receptor
 UniProt Gene Name    TSHR [Similar Products]
 UniProt Synonym Gene Names    TSH-R [Similar Products]
 UniProt Entry Name    TSHR_BOVIN
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 UniProt Comments for TSHR    Function: Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
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 Research Articles on TSHR    1. Localization of thyrotropin receptor and thyroglobulin in the bovine corpus luteum.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TSHR elisa kitPathways associated with TSHR elisa kit
 Reference Product  PubMed Publications
 FLNA elisa kit  >12 publications with TSHR and FLNA
 Products by Pathway  Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Hormone Ligand-binding Receptors Pathway antibodies  Hormone Ligand-binding Receptors Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
Diseases associated with TSHR elisa kitOrgans/Tissues associated with TSHR elisa kit
 Disease Name  Pubmed Publications
 Hyperthyroidism Antibodies  >494 publications with TSHR and Hyperthyroidism
 Graves Disease Antibodies  >453 publications with TSHR and Graves Disease
 Thyroid Neoplasms Antibodies  >161 publications with TSHR and Thyroid Neoplasms
 Thyroiditis, Autoimmune Antibodies  >107 publications with TSHR and Thyroiditis, Autoimmune
 Carcinoma Antibodies  >95 publications with TSHR and Carcinoma
 Congenital Hypothyroidism Antibodies  >73 publications with TSHR and Congenital Hypothyroidism
 Adenoma Antibodies  >49 publications with TSHR and Adenoma
 Thyrotoxicosis Antibodies  >40 publications with TSHR and Thyrotoxicosis
 Kidney Diseases Antibodies  >38 publications with TSHR and Kidney Diseases
 Inflammation Antibodies  >26 publications with TSHR and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with TSHR and Bone
 Connective Tissue Antibodies  >4 publications with TSHR and Connective Tissue
 Heart Antibodies  >3 publications with TSHR and Heart
 Muscle Antibodies  >3 publications with TSHR and Muscle
 Brain Antibodies  >3 publications with TSHR and Brain
 Vascular Antibodies  >2 publications with TSHR and Vascular
 Embryonic Tissue Antibodies  >2 publications with TSHR and Embryonic Tissue
 Ear Antibodies  >1 publications with TSHR and Ear
 Kidney Antibodies  >1 publications with TSHR and Kidney
 Umbilical Cord Antibodies  >1 publications with TSHR and Umbilical Cord
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