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TLR6 elisa kit :: Human toll-like receptor 6 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS705756 TLR6 elisa kit
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

toll-like receptor 6 (TLR6), ELISA Kit

★Popular Item★
 Also Known As   

Human Soluble Toll-like Receptor 6, TLR-6 ELISA Kit

 Product Synonym Names    Human Soluble Toll-like Receptor 6 (TLR-6) ELISA Kit; CD286; OTTHUMP00000158730; toll-like receptor 6
 Product Gene Name   

TLR6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    605403
 3D Structure    ModBase 3D Structure for Q9Y2C9
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human TLR-6. No significant cross-reactivity or interference between human TLR-6 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Quantitative Sandwich
 Detection Range    62.5 pg/ml -4000 pg/ml
 Sensitivity    Typically less than 15.6 pg/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TLR6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TLR6 purchase    MBS705756 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the toll-like receptor 6 (TLR6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5 pg/ml -4000 pg/ml in biological research samples containing TLR6, with an estimated sensitivity of Typically less than 15.6 pg/ml. The ELISA analytical biochemical technique of the MBS705756 kit is based on TLR6 antibody-TLR6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TLR6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TLR6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TLR6 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TLR-6 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TLR-6 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TLR-6 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TLR-6 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS705756. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TLR6. It may not necessarily be applicable to this product.
 NCBI GI #    20143971
 NCBI GeneID    10333
 NCBI Accession #    NP_006059.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006068.4 [Other Products]
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 UniProt Primary Accession #    Q9Y2C9 [Other Products]
 UniProt Secondary Accession #    B3Y640; B6CH35; B6RFS4; B6RFS5 [Other Products]
 UniProt Related Accession #    Q9Y2C9 [Other Products]
 Molecular Weight    91,880 Da
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 NCBI Official Full Name    toll-like receptor 6
 NCBI Official Synonym Full Names    toll-like receptor 6
 NCBI Official Symbol    TLR6 [Similar Products]
 NCBI Official Synonym Symbols   
CD286
[Similar Products]
 NCBI Protein Information    toll-like receptor 6
 UniProt Protein Name    Toll-like receptor 6
 UniProt Synonym Protein Names   
CD_antigen: CD286
 Protein Family    Toll-like receptor
 UniProt Gene Name    TLR6 [Similar Products]
 UniProt Entry Name    TLR6_HUMAN
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 NCBI Summary for TLR6    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.[provided by RefSeq, Jan 2011]
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 UniProt Comments for TLR6    Function: Participates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.1 PublicationManual assertion based on experiment in:Ref.6
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 Research Articles on TLR6    1. In the genetic association analysis, polymorphisms in TLR1 (S248N and R80T), TLR2 (P631H), and TLR6 (P249S) were associated with an increased susceptibility to complicated skin and skin structure infections.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TLR6 elisa kitPathways associated with TLR6 elisa kit
 Reference Product  PubMed Publications
 TLR2 elisa kit  >440 publications with TLR6 and TLR2
 TLR1 elisa kit  >312 publications with TLR6 and TLR1
 MYD88 elisa kit  >86 publications with TLR6 and MYD88
 CD14 elisa kit  >60 publications with TLR6 and CD14
 LY96 elisa kit  >8 publications with TLR6 and LY96
 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 MyD88:Mal Cascade Initiated On Plasma Membrane Pathway antibodies  MyD88:Mal Cascade Initiated On Plasma Membrane Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Regulation Of Toll-like Receptor Signaling Pathway antibodies  Regulation Of Toll-like Receptor Signaling Pathway Diagram
 Toll Like Receptor 2 (TLR2) Cascade Pathway antibodies  Toll Like Receptor 2 (TLR2) Cascade Pathway Diagram
Diseases associated with TLR6 elisa kitOrgans/Tissues associated with TLR6 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >138 publications with TLR6 and Inflammation
 Necrosis Antibodies  >91 publications with TLR6 and Necrosis
 Immune System Diseases Antibodies  >67 publications with TLR6 and Immune System Diseases
 Cardiovascular Diseases Antibodies  >15 publications with TLR6 and Cardiovascular Diseases
 Liver Diseases Antibodies  >10 publications with TLR6 and Liver Diseases
 Kidney Diseases Antibodies  >10 publications with TLR6 and Kidney Diseases
 Atherosclerosis Antibodies  >8 publications with TLR6 and Atherosclerosis
 Neoplasms, Experimental Antibodies  >7 publications with TLR6 and Neoplasms, Experimental
 Prostatic Neoplasms Antibodies  >7 publications with TLR6 and Prostatic Neoplasms
 Hepatitis Antibodies  >5 publications with TLR6 and Hepatitis
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with TLR6 and Bone
 Connective Tissue Antibodies  >4 publications with TLR6 and Connective Tissue
 Heart Antibodies  >3 publications with TLR6 and Heart
 Muscle Antibodies  >3 publications with TLR6 and Muscle
 Brain Antibodies  >3 publications with TLR6 and Brain
 Vascular Antibodies  >2 publications with TLR6 and Vascular
 Embryonic Tissue Antibodies  >2 publications with TLR6 and Embryonic Tissue
 Ear Antibodies  >1 publications with TLR6 and Ear
 Kidney Antibodies  >1 publications with TLR6 and Kidney
 Umbilical Cord Antibodies  >1 publications with TLR6 and Umbilical Cord
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