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TGFB1I1 elisa kit :: Human transforming growth factor beta 1 induced transcript 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9343318 TGFB1I1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

transforming growth factor beta 1 induced transcript 1 (TGFB1I1), ELISA Kit

★Popular Item★
 Also Known As   

Human Transforming growth factor beta-1-induced transcript 1 protein, TGFB1I1 ELISA Kit

 Product Synonym Names    Human Transforming growth factor beta-1-induced transcript 1 protein (TGFB1I1) ELISA kit; ARA55; HIC-5; HIC5; TSC-5; androgen receptor coactivator ARA55; androgen receptor-associated protein of 55 kDa; hydrogen peroxide-inducible clone 5 protein; transforming growth factor beta 1 induced transcript 1
 Product Gene Name   

TGFB1I1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    602353
 3D Structure    ModBase 3D Structure for O43294
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    0.625 ng/ml - 20 ng/ml
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TGFB1I1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TGFB1I1 purchase    MBS9343318 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the transforming growth factor beta 1 induced transcript 1 (TGFB1I1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing TGFB1I1, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9343318 kit is based on TGFB1I1 antibody-TGFB1I1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TGFB1I1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TGFB1I1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TGFB1I1 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TGFB1I1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9343318. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TGFB1I1. It may not necessarily be applicable to this product.
 NCBI GI #    109638745
 NCBI GeneID    7041
 NCBI Accession #    NP_001035919.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042454.2 [Other Products]
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 UniProt Primary Accession #    O43294 [Other Products]
 UniProt Secondary Accession #    Q9BPW3; Q9Y2V5; B2R8D5 [Other Products]
 UniProt Related Accession #    O43294 [Other Products]
 Molecular Weight    49,814 Da
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 NCBI Official Full Name    transforming growth factor beta-1-induced transcript 1 protein isoform 1
 NCBI Official Synonym Full Names    transforming growth factor beta 1 induced transcript 1
 NCBI Official Symbol    TGFB1I1 [Similar Products]
 NCBI Official Synonym Symbols   
HIC5; ARA55; HIC-5; TSC-5
[Similar Products]
 NCBI Protein Information    transforming growth factor beta-1-induced transcript 1 protein; androgen receptor coactivator ARA55; hydrogen peroxide-inducible clone 5 protein; androgen receptor coactivator 55 kDa protein; androgen receptor-associated protein of 55 kDa
 UniProt Protein Name    Transforming growth factor beta-1-induced transcript 1 protein
 UniProt Synonym Protein Names   
Androgen receptor coactivator 55 kDa protein; Androgen receptor-associated protein of 55 kDa; Hydrogen peroxide-inducible clone 5 protein; Hic-5
 Protein Family    Transforming growth factor beta-1-induced transcript 1 protein
 UniProt Gene Name    TGFB1I1 [Similar Products]
 UniProt Synonym Gene Names    ARA55; Hic-5 [Similar Products]
 UniProt Entry Name    TGFI1_HUMAN
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 NCBI Summary for TGFB1I1    This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
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 UniProt Comments for TGFB1I1    Hic-5: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA- binding activity. Homooligomer. Interacts with CRIP2, HSPB1, ILK, LIMS1, LIMS2, NCK2, NUDT16L1, PAK, PPARG, PTPN12, TCF3, TCF7L2 and VCL. Forms a complex with GIT1 and ARHGEF7. Interacts with AR/androgen receptor in a ligand-dependent manner. Interacts with CSK, LYN, MAPK15, NR3C1, PPARG, PTK2/FAK1, PTK2B/PYK2, SLC6A3, SLC6A4, SMAD3, SRC and talin. Up-regulated by TNF and hydrogen peroxide. Expressed in platelets, smooth muscle and prostate stromal cells. Belongs to the paxillin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Transcription, coactivator/corepressor; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: extracellular matrix; focal adhesion; cytoskeleton; nuclear matrix; cytoplasm; intracellular

Molecular Function: protein binding; Roundabout binding; androgen receptor binding; zinc ion binding; transcription coactivator activity

Biological Process: transcription from RNA polymerase II promoter; Wnt receptor signaling pathway; cell fate commitment; positive regulation of transcription, DNA-dependent; positive regulation of transforming growth factor beta receptor signaling pathway; negative regulation of fat cell differentiation; ubiquitin-dependent SMAD protein catabolic process; negative regulation of cell proliferation; morphogenesis of embryonic epithelium; epithelial cell differentiation; response to heat; androgen receptor signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; cell adhesion
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 Research Articles on TGFB1I1    1. The ubiquitin ligase activity of Cbl-c by the direct interaction of the LIM zinc coordinating domain of Hic5 is demonstrated.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TGFB1I1 elisa kitPathways associated with TGFB1I1 elisa kit
 Reference Product  PubMed Publications
 PTK2 elisa kit  >10 publications with TGFB1I1 and PTK2
 PTK2B elisa kit  >4 publications with TGFB1I1 and PTK2B
 SMAD3 elisa kit  >4 publications with TGFB1I1 and SMAD3
 PTPN12 elisa kit  >3 publications with TGFB1I1 and PTPN12
 GIT1 elisa kit  >3 publications with TGFB1I1 and GIT1
 TRAF4 elisa kit  >2 publications with TGFB1I1 and TRAF4
 HSPB1 elisa kit  >2 publications with TGFB1I1 and HSPB1
 TGFBR2 elisa kit  >1 publications with TGFB1I1 and TGFBR2
 SVIL elisa kit  >1 publications with TGFB1I1 and SVIL
 SLC6A3 elisa kit  >1 publications with TGFB1I1 and SLC6A3
 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Coregulation Of Androgen Receptor Activity Pathway antibodies  Coregulation Of Androgen Receptor Activity Pathway Diagram
 Monoamine Transport Pathway antibodies  Monoamine Transport Pathway Diagram
Diseases associated with TGFB1I1 elisa kitOrgans/Tissues associated with TGFB1I1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >24 publications with TGFB1I1 and Neoplasms
 Necrosis Antibodies  >5 publications with TGFB1I1 and Necrosis
 Fibrosis Antibodies  >4 publications with TGFB1I1 and Fibrosis
 Cell Transformation, Neoplastic Antibodies  >4 publications with TGFB1I1 and Cell Transformation, Neoplastic
 Thrombosis Antibodies  >3 publications with TGFB1I1 and Thrombosis
 Nervous System Diseases Antibodies  >3 publications with TGFB1I1 and Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with TGFB1I1 and Brain Diseases
 Disease Models, Animal Antibodies  >2 publications with TGFB1I1 and Disease Models, Animal
 Pain Antibodies  >2 publications with TGFB1I1 and Pain
 Hypertrophy Antibodies  >2 publications with TGFB1I1 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >22 publications with TGFB1I1 and Prostate
 Muscle Antibodies  >17 publications with TGFB1I1 and Muscle
 Vascular Antibodies  >11 publications with TGFB1I1 and Vascular
 Embryonic Tissue Antibodies  >6 publications with TGFB1I1 and Embryonic Tissue
 Kidney Antibodies  >6 publications with TGFB1I1 and Kidney
 Connective Tissue Antibodies  >4 publications with TGFB1I1 and Connective Tissue
 Skin Antibodies  >4 publications with TGFB1I1 and Skin
 Lung Antibodies  >3 publications with TGFB1I1 and Lung
 Heart Antibodies  >3 publications with TGFB1I1 and Heart
 Bone Antibodies  >3 publications with TGFB1I1 and Bone
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