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TMC2 elisa kit :: Human transmembrane channel-like 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9333596 TMC2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

transmembrane channel-like 2 (TMC2), ELISA Kit

 Also Known As   

Human Transmembrane channel-like protein 2, TMC2 ELISA Kit

 Product Synonym Names    Human Transmembrane channel-like protein 2 (TMC2) ELISA kit; RP4-686C3.3; C20orf145; dJ686C3.3; transmembrane cochlear-expressed protein 2; transmembrane; cochlear expressed; 2; transmembrane channel-like 2
 Product Gene Name   

TMC2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    606707
 3D Structure    ModBase 3D Structure for Q8TDI7
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TMC2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TMC2 purchase    MBS9333596 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the transmembrane channel-like 2 (TMC2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TMC2. The ELISA analytical biochemical technique of the MBS9333596 kit is based on TMC2 antibody-TMC2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TMC2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TMC2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TMC2. It may not necessarily be applicable to this product.
 NCBI GI #    94536852
 NCBI GeneID    117532
 NCBI Accession #    NP_542789.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_080751.2 [Other Products]
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 UniProt Primary Accession #    Q8TDI7 [Other Products]
 UniProt Secondary Accession #    Q5JXT0; Q5JXT1; Q6UWW4; Q6ZS41; Q8N9F3; Q9BYN2; Q9BYN3; Q9BYN4; Q9BYN5 [Other Products]
 UniProt Related Accession #    Q8TDI7 [Other Products]
 Molecular Weight    102,610 Da
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 NCBI Official Full Name    transmembrane channel-like protein 2
 NCBI Official Synonym Full Names    transmembrane channel-like 2
 NCBI Official Symbol    TMC2 [Similar Products]
 NCBI Official Synonym Symbols   
C20orf145; dJ686C3.3
[Similar Products]
 NCBI Protein Information    transmembrane channel-like protein 2; transmembrane, cochlear expressed, 2; transmembrane cochlear-expressed protein 2
 UniProt Protein Name    Transmembrane channel-like protein 2
 UniProt Synonym Protein Names   
Transmembrane cochlear-expressed protein 2
 UniProt Gene Name    TMC2 [Similar Products]
 UniProt Synonym Gene Names    C20orf145; UNQ907/PRO1928 [Similar Products]
 UniProt Entry Name    TMC2_HUMAN
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 NCBI Summary for TMC2    This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, expression in the inner ear suggests that it may be crucial for normal auditory function. Mutations in this gene may underlie hereditary disorders of balance and hearing. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TMC2    TMC2: May be required for the normal function of cochlear hair cells. Belongs to the TMC family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: integral to membrane; stereocilium bundle tip

Molecular Function: voltage-gated calcium channel activity

Biological Process: vestibular reflex; detection of mechanical stimulus involved in sensory perception of sound
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 Research Articles on TMC2    1. Autozygosity by descent analysis of 2 markers bordering the TMC2 gene allowed us to rule out its association with deafness within these families.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with TMC2 elisa kitOrgans/Tissues associated with TMC2 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with TMC2 and Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with TMC2 and Brain
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