NP_001269914.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,009 Da
NCBI Official Full Name
tribbles homolog 1 isoform 2
NCBI Official Synonym Full Names
tribbles pseudokinase 1
NCBI Official Synonym Symbols
C8FW; GIG2; TRB1; GIG-2; SKIP1; TRB-1 [Similar Products]
NCBI Protein Information
tribbles homolog 1; tribbles-like protein 1; G-protein-coupled receptor induced protein; G-protein-coupled receptor-induced protein 2; phosphoprotein regulated by mitogenic pathways; G-protein-coupled receptor-induced gene 2 protein
UniProt Protein Name
Tribbles homolog 1
UniProt Synonym Protein Names
G-protein-coupled receptor-induced gene 2 protein; GIG-2; SKIP1
UniProt Synonym Gene Names
UniProt Entry Name
TRIB1_HUMAN
UniProt Comments for TRIB1
TRB1: Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; Kinase, protein; CAMK group; Trbl family
Chromosomal Location of Human Ortholog: 8q24.13
Cellular Component: cytoplasm; nucleus
Molecular Function: protein kinase inhibitor activity; mitogen-activated protein kinase kinase binding; ubiquitin protein ligase binding; ubiquitin-protein ligase regulator activity; transcription factor binding; ATP binding; protein kinase activity
Biological Process: negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of smooth muscle cell proliferation; regulation of MAP kinase activity; negative regulation of transcription factor activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; JNK cascade; negative regulation of protein kinase activity; response to lipopolysaccharide; negative regulation of smooth muscle cell migration; protein amino acid phosphorylation
Research Articles on TRIB1
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Diseases associated with TRIB1 elisa kit
Organs/Tissues associated with TRIB1 elisa kit
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