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TNNT1 elisa kit :: Human troponin T type 1 (skeletal, slow) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS700509
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

troponin T type 1 (skeletal, slow) (TNNT1), ELISA Kit

★Popular Item★
 Also Known As   

Human cardiac troponin T, cTn-T ELISA Kit

 Product Synonym Names    Human cardiac troponin T (cTn-T) ELISA Kit; ANM; FLJ98147; MGC104241; STNT; TNT; TNTS; slow skeletal muscle troponin T; troponin T1; skeletal; slow; troponin-T1; skeletal; slow; troponin T type 1 (skeletal; slow)
 Product Gene Name   

TNNT1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS700509 Testing Data    Testing Data PDF
 OMIM    gene 605355
 3D Structure    ModBase 3D Structure for P13805
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human TNNT1. No significant cross-reactivity or interference between Human TNNT1 and analogues was observed.
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 Samples    Serum, plasma
 Assay Type    Sandwich
 Detection Range    0.156 ng/ml-10 ng/ml
 Sensitivity    0.039 ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TNNT1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TNNT1 purchase    MBS700509 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the troponin T type 1 (skeletal, slow) (TNNT1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156 ng/ml-10 ng/ml in biological research samples containing TNNT1, with an estimated sensitivity of 0.039 ng/ml. The ELISA analytical biochemical technique of the MBS700509 kit is based on TNNT1 antibody-TNNT1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNNT1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TNNT1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). Both cardiac and skeletal muscle fibers are composed of highly structured type cells. Key structural components are cytoskeletal proteins and molecular motors. The actin binding protein; Troponin T cTN-T along with related troponin type 1 and C (TNNT) slow skeletal muscle contraction through EF hand calcium binding. Further, clinically relevant increases are diagnostic for myocardial infarctions (MI). Homo sapiens and mus musculus mouse genome share significant gene sequence identity but vary at the organism level (see Pubmed database). Thus a precision ELISA assay with 1000pg ml sensitivity for human samples will aid life science studies. Reliable intra assay results. recombinant troponin as standard and all inclusive of antibody products allow use of our kit for comparative studies with ICC IHC. We offer this Cloud Clone Corp product at value pricing for your troponin type T ELISA kit requirement. We are please to stock other Troponin slow skeletal ELISA kit (s).
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Related Product Information for TNNT1 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for cTn-T has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any cTn-T present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for cTn-T is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of cTn-T bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of TNNT1 elisa kit    TNNT1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS700509. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TNNT1. It may not necessarily be applicable to this product.
 NCBI GI #    187173290
 NCBI GeneID    7138
 NCBI Accession #    NP_001119604.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001126132.2 [Other Products]
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 UniProt Primary Accession #    P13805 [Other Products]
 UniProt Secondary Accession #    O95472; Q16061; Q5U0E1 [Other Products]
 UniProt Related Accession #    P13805 [Other Products]
 Molecular Weight    32,948 Da
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 NCBI Official Full Name    troponin T, slow skeletal muscle isoform b
 NCBI Official Synonym Full Names    troponin T type 1 (skeletal, slow)
 NCBI Official Symbol    TNNT1 [Similar Products]
 NCBI Official Synonym Symbols   
ANM; TNT; NEM5; STNT; TNTS
[Similar Products]
 NCBI Protein Information    troponin T, slow skeletal muscle; troponin-T1, skeletal, slow; slow skeletal muscle troponin T
 UniProt Protein Name    Troponin T, slow skeletal muscle
 UniProt Synonym Protein Names   
Slow skeletal muscle troponin T; sTnT
 Protein Family    Troponin
 UniProt Gene Name    TNNT1 [Similar Products]
 UniProt Synonym Gene Names    TNT; TnTs; sTnT [Similar Products]
 UniProt Entry Name    TNNT1_HUMAN
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 NCBI Summary for TNNT1    This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TNNT1    Function: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
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 Research Articles on TNNT1    1. Troponin T1 blood levels had a positive association with increased risk for hypertrophic cardiomyopathy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TNNT1 elisa kitPathways associated with TNNT1 elisa kit
 Reference Product  PubMed Publications
 NEB elisa kit  >10 publications with TNNT1 and NEB
 TPM2 elisa kit  >10 publications with TNNT1 and TPM2
 TNNI2 elisa kit  >3 publications with TNNT1 and TNNI2
 TNNI3 elisa kit  >2 publications with TNNT1 and TNNI3
 TNNC1 elisa kit  >1 publications with TNNT1 and TNNC1
 TNNI1 elisa kit  >1 publications with TNNT1 and TNNI1
 TPM1 elisa kit  >1 publications with TNNT1 and TPM1
 Products by Pathway  Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
Diseases associated with TNNT1 elisa kitOrgans/Tissues associated with TNNT1 elisa kit
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >3 publications with TNNT1 and Brain Diseases
 Disease Models, Animal Antibodies  >2 publications with TNNT1 and Disease Models, Animal
 Neurotoxicity Syndromes Antibodies  >1 publications with TNNT1 and Neurotoxicity Syndromes
 Neoplasm Metastasis Antibodies  >1 publications with TNNT1 and Neoplasm Metastasis
 Weight Loss Antibodies  >1 publications with TNNT1 and Weight Loss
 Inflammation Antibodies  >1 publications with TNNT1 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with TNNT1 and Bone
 Connective Tissue Antibodies  >4 publications with TNNT1 and Connective Tissue
 Heart Antibodies  >3 publications with TNNT1 and Heart
 Muscle Antibodies  >3 publications with TNNT1 and Muscle
 Brain Antibodies  >3 publications with TNNT1 and Brain
 Vascular Antibodies  >2 publications with TNNT1 and Vascular
 Embryonic Tissue Antibodies  >2 publications with TNNT1 and Embryonic Tissue
 Ear Antibodies  >1 publications with TNNT1 and Ear
 Kidney Antibodies  >1 publications with TNNT1 and Kidney
 Umbilical Cord Antibodies  >1 publications with TNNT1 and Umbilical Cord
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