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TUBA8 elisa kit :: Human tubulin, alpha 8 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9327019 TUBA8 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

tubulin, alpha 8 (TUBA8), ELISA Kit

 Also Known As   

Human Tubulin alpha-8 chain, TUBA8 ELISA Kit

 Product Synonym Names    Human Tubulin alpha-8 chain (TUBA8) ELISA kit; TUBAL2; tubulin; alpha-like 2; tubulin; alpha 8
 Product Gene Name   

TUBA8 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 613180
 3D Structure    ModBase 3D Structure for Q9NY65
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TUBA8 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TUBA8 purchase    MBS9327019 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the tubulin, alpha 8 (TUBA8) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TUBA8. The ELISA analytical biochemical technique of the MBS9327019 kit is based on TUBA8 antibody-TUBA8 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TUBA8 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TUBA8. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TUBA8. It may not necessarily be applicable to this product.
 NCBI GI #    261878539
 NCBI GeneID    1962
 NCBI Accession #    NP_001159887.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001166415.1 [Other Products]
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 UniProt Primary Accession #    Q9NY65 [Other Products]
 UniProt Secondary Accession #    Q2M3N4; B2RCX2; B3KPW9; B4DWG3 [Other Products]
 UniProt Related Accession #    Q08426 [Other Products]
 Molecular Weight    42,954 Da
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 NCBI Official Full Name    peroxisomal bifunctional enzyme isoform 2
 NCBI Official Synonym Full Names    enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
 NCBI Official Symbol    EHHADH [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    peroxisomal bifunctional enzyme; PBE; 3,2-trans-enoyl-CoA isomerase; peroxisomal enoyl-CoA hydratase; L-3-hydroxyacyl-CoA dehydrogenase; L-bifunctional protein, peroxisomal; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase
 UniProt Protein Name    Tubulin alpha-8 chain
 UniProt Synonym Protein Names   
Alpha-tubulin 8; Tubulin alpha chain-like 2
 UniProt Gene Name    TUBA8 [Similar Products]
 UniProt Synonym Gene Names    TUBAL2 [Similar Products]
 UniProt Entry Name    TBA8_HUMAN
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 NCBI Summary for TUBA8    The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
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 UniProt Comments for TUBA8    TUBA8: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Defects in TUBA8 are the cause of polymicrogyria with optic nerve hypoplasia (PMGONH). It is a disease characterized by extensive polymicrogyria, optic nerve hypoplasia, severe developmental delay, hypotonia, seizures, a dysplastic or absent corpus callosum and colpocephaly. Polymicrogyria is a malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination. Belongs to the tubulin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 22q11.1

Cellular Component: microtubule; cytoplasm

Molecular Function: GTPase activity; GTP binding; structural constituent of cytoskeleton

Biological Process: protein polymerization; metabolic process; microtubule-based process

Disease: Polymicrogyria With Optic Nerve Hypoplasia
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 Research Articles on TUBA8    1. Mistargeting of peroxisomal EHHADH disrupts mitochondrial metabolism and leads to renal Fanconi's syndrome; this indicates a central role of mitochondria in proximal tubular function.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TUBA8 elisa kitDiseases associated with TUBA8 elisa kit
 Products by Pathway  Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Lysine Degradation, Lysine => Saccharopine => Acetoacetyl-CoA Pathway antibodies  Lysine Degradation, Lysine => Saccharopine => Acetoacetyl-CoA Pathway Diagram
 Lysine Degradation, Lysine => Saccharopine => Acetoacetyl-CoA Pathway antibodies  Lysine Degradation, Lysine => Saccharopine => Acetoacetyl-CoA Pathway Diagram
 Malonate Semialdehyde Pathway, Propanoyl-CoA => Acetyl-CoA antibodies  Malonate Semialdehyde Pathway, Propanoyl-CoA => Acetyl-CoA Diagram
 Malonate Semialdehyde Pathway, Propanoyl-CoA => Acetyl-CoA antibodies  Malonate Semialdehyde Pathway, Propanoyl-CoA => Acetyl-CoA Diagram
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >3 publications with TUBA8 and Fatty Liver
 Abnormalities, Drug-Induced Antibodies  >2 publications with TUBA8 and Abnormalities, Drug-Induced
 Drug Toxicity Antibodies  >2 publications with TUBA8 and Drug Toxicity
 Disease Models, Animal Antibodies  >1 publications with TUBA8 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >1 publications with TUBA8 and Cardiovascular Diseases
 Liver Diseases Antibodies  >1 publications with TUBA8 and Liver Diseases
 Hypertension Antibodies  >1 publications with TUBA8 and Hypertension
 Neoplasms Antibodies  >1 publications with TUBA8 and Neoplasms
 Necrosis Antibodies  >1 publications with TUBA8 and Necrosis
Organs/Tissues associated with TUBA8 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with TUBA8 and Kidney
 Testis Antibodies  >1 publications with TUBA8 and Testis
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