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TTLL5 elisa kit :: Human tubulin tyrosine ligase-like family, member 5 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9339757 TTLL5 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

tubulin tyrosine ligase-like family, member 5 (TTLL5), ELISA Kit

 Also Known As   

Human Tubulin polyglutamylase TTLL5, TTLL5 ELISA Kit

 Product Synonym Names    Human Tubulin polyglutamylase TTLL5 (TTLL5) ELISA kit; KIAA0998; MGC117189; STAMP; SRC1 and TIF2 associated binding protein; tubulin tyrosine ligase-like family; member 5
 Product Gene Name   

TTLL5 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    612268
 3D Structure    ModBase 3D Structure for Q6EMB2
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TTLL5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TTLL5 purchase    MBS9339757 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the tubulin tyrosine ligase-like family, member 5 (TTLL5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TTLL5. The ELISA analytical biochemical technique of the MBS9339757 kit is based on TTLL5 antibody-TTLL5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TTLL5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TTLL5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TTLL5. It may not necessarily be applicable to this product.
 NCBI GI #    50658079
 NCBI GeneID    23093
 NCBI Accession #    NP_055887.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_015072.4 [Other Products]
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 UniProt Primary Accession #    Q6EMB2 [Other Products]
 UniProt Secondary Accession #    Q9BUB0; Q9H0G4; Q9H7W2; Q9P1V5; Q9UPZ4; B9EGH8; B9EGH9 [Other Products]
 UniProt Related Accession #    Q6EMB2 [Other Products]
 Molecular Weight    143,577 Da
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 NCBI Official Full Name    tubulin polyglutamylase TTLL5
 NCBI Official Synonym Full Names    tubulin tyrosine ligase-like family, member 5
 NCBI Official Symbol    TTLL5 [Similar Products]
 NCBI Official Synonym Symbols   
STAMP; CORD19; KIAA0998
[Similar Products]
 NCBI Protein Information    tubulin polyglutamylase TTLL5; SRC1 and TIF2 associated binding protein; SRC1 and TIF2-associated modulatory protein
 UniProt Protein Name    Tubulin polyglutamylase TTLL5
 UniProt Synonym Protein Names   
SRC1 and TIF2-associated modulatory protein; Tubulin--tyrosine ligase-like protein 5
 Protein Family    Tubulin polyglutamylase
 UniProt Gene Name    TTLL5 [Similar Products]
 UniProt Synonym Gene Names    KIAA0998; STAMP [Similar Products]
 UniProt Entry Name    TTLL5_HUMAN
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 NCBI Summary for TTLL5    This gene encodes a member of the tubulin tyrosine ligase like protein family. This protein interacts with two glucocorticoid receptor coactivators, transcriptional intermediary factor 2 and steroid receptor coactivator 1. This protein may function as a coregulator of glucocorticoid receptor mediated gene induction and repression. This protein may also function as an alpha tubulin polyglutamylase.[provided by RefSeq, Feb 2010]
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 UniProt Comments for TTLL5    TTLL5: Polyglutamylase which preferentially modifies alpha- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for CCSAP localization to both spindle and cilia microtubules. Increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction. Belongs to the tubulin--tyrosine ligase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Ligase; EC 6.-.-.-

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: centrosome; cytoplasm; nucleus; cilium

Molecular Function: ligase activity

Biological Process: protein polyglutamylation; sperm motility; fertilization; transcription, DNA-dependent; sperm axoneme assembly

Disease: Cone-rod Dystrophy 19
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 Research Articles on TTLL5    1. this study has performed exome sequencing in 28 individuals with a similar disease phenotype and subsequently used a casecontrol approach to identify mutations in TTLL5 as a cause of recessive retinal dystrophy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with TTLL5 elisa kitOrgans/Tissues associated with TTLL5 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with TTLL5 and Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with TTLL5 and Cell Transformation, Neoplastic
 Kidney Neoplasms Antibodies  >1 publications with TTLL5 and Kidney Neoplasms
 Kidney Diseases Antibodies  >1 publications with TTLL5 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >2 publications with TTLL5 and Kidney
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