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TNFSF9 elisa kit :: Human tumor necrosis factor (ligand) superfamily, member 9 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS932847
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,550 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,815 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

tumor necrosis factor (ligand) superfamily, member 9 (TNFSF9), ELISA Kit

 Also Known As   

Human Tumor necrosis factor ligand superfamily member 9, TNFSF9 ELISA Kit

 Product Synonym Names    Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9) ELISA kit; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; tumor necrosis factor (ligand) superfamily; member 9
 Product Gene Name   

TNFSF9 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 MBS932847 Testing Data    Testing Data PDF
 OMIM    606182
 3D Structure    ModBase 3D Structure for P41273
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human TNFSF9. No significant cross-reactivity or interference between Human TNFSF9 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    18.75 pg/ml-1200 pg/ml
 Sensitivity    4.68 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TNFSF9 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TNFSF9 purchase    MBS932847 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the tumor necrosis factor (ligand) superfamily, member 9 (TNFSF9) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 18.75 pg/ml-1200 pg/ml in biological research samples containing TNFSF9, with an estimated sensitivity of 4.68 pg/ml. The ELISA analytical biochemical technique of the MBS932847 kit is based on TNFSF9 antibody-TNFSF9 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNFSF9 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TNFSF9. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for TNFSF9 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TNFSF9 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TNFSF9 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TNFSF9 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TNFSF9 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of TNFSF9 elisa kit    TNFSF9 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS932847
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NCBI/Uniprot data below describe general gene information for TNFSF9. It may not necessarily be applicable to this product.
 NCBI GI #    4507609
 NCBI GeneID    8744
 NCBI Accession #    NP_003802.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003811.3 [Other Products]
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 UniProt Primary Accession #    P41273 [Other Products]
 UniProt Secondary Accession #    Q2M3S2 [Other Products]
 UniProt Related Accession #    P41273 [Other Products]
 Molecular Weight    26,625 Da
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 NCBI Official Full Name    tumor necrosis factor ligand superfamily member 9
 NCBI Official Synonym Full Names    tumor necrosis factor (ligand) superfamily, member 9
 NCBI Official Symbol    TNFSF9 [Similar Products]
 NCBI Official Synonym Symbols   
CD137L; 4-1BB-L
[Similar Products]
 NCBI Protein Information    tumor necrosis factor ligand superfamily member 9; 4-1BBL; 4-1BB ligand; receptor 4-1BB ligand; homolog of mouse 4-1BB-L
 UniProt Protein Name    Tumor necrosis factor ligand superfamily member 9
 UniProt Synonym Protein Names   
4-1BB ligand; 4-1BBL
 Protein Family    Tumor necrosis factor ligand superfamily
 UniProt Gene Name    TNFSF9 [Similar Products]
 UniProt Synonym Gene Names    4-1BBL [Similar Products]
 UniProt Entry Name    TNFL9_HUMAN
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 NCBI Summary for TNFSF9    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008]
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 UniProt Comments for TNFSF9    TNFL9: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. Belongs to the tumor necrosis factor family.

Protein type: Cell cycle regulation; Apoptosis; Cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular space; integral to membrane; plasma membrane

Molecular Function: cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: cell proliferation; positive regulation of interferon-gamma production; positive regulation of cytotoxic T cell differentiation; cell-cell signaling; positive regulation of interleukin-12 production; apoptosis; positive regulation of interleukin-6 production; myeloid dendritic cell differentiation; immune response; positive regulation of activated T cell proliferation; signal transduction
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 Research Articles on TNFSF9    1. monocytes interact with iNKT cells to increase expression of 4-1BBL and 4-1BB, and in conjunction with this pathway, maintain their numbers at baseline.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TNFSF9 elisa kitPathways associated with TNFSF9 elisa kit
 Reference Product  PubMed Publications
 TNFRSF9 elisa kit  >76 publications with TNFSF9 and TNFRSF9
 CD40 elisa kit  >17 publications with TNFSF9 and CD40
 TNFSF4 elisa kit  >14 publications with TNFSF9 and TNFSF4
 CD70 elisa kit  >9 publications with TNFSF9 and CD70
 ICAM1 elisa kit  >5 publications with TNFSF9 and ICAM1
 TRAF2 elisa kit  >2 publications with TNFSF9 and TRAF2
 TRAF1 elisa kit  >1 publications with TNFSF9 and TRAF1
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with TNFSF9 elisa kitOrgans/Tissues associated with TNFSF9 elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >129 publications with TNFSF9 and Necrosis
 Disease Models, Animal Antibodies  >18 publications with TNFSF9 and Disease Models, Animal
 Inflammation Antibodies  >16 publications with TNFSF9 and Inflammation
 Gastrointestinal Diseases Antibodies  >14 publications with TNFSF9 and Gastrointestinal Diseases
 Neoplasms, Experimental Antibodies  >14 publications with TNFSF9 and Neoplasms, Experimental
 Liver Diseases Antibodies  >11 publications with TNFSF9 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >5 publications with TNFSF9 and Carcinoma, Hepatocellular
 Lung Neoplasms Antibodies  >5 publications with TNFSF9 and Lung Neoplasms
 Nervous System Diseases Antibodies  >4 publications with TNFSF9 and Nervous System Diseases
 Heart Diseases Antibodies  >3 publications with TNFSF9 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >110 publications with TNFSF9 and Blood
 Nerve Antibodies  >53 publications with TNFSF9 and Nerve
 Bone Antibodies  >10 publications with TNFSF9 and Bone
 Eye Antibodies  >4 publications with TNFSF9 and Eye
 Stomach Antibodies  >3 publications with TNFSF9 and Stomach
 Intestine Antibodies  >3 publications with TNFSF9 and Intestine
 Brain Antibodies  >3 publications with TNFSF9 and Brain
 Prostate Antibodies  >1 publications with TNFSF9 and Prostate
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