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RALA elisa kit :: Human v-ral simian leukemia viral oncogene homolog A (ras related) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9330319 RALA elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

v-ral simian leukemia viral oncogene homolog A (ras related) (RALA), ELISA Kit

★Popular Item★
 Also Known As   

Human Ras-related protein Ral-A, RALA ELISA Kit

 Product Synonym Names    Human Ras-related protein Ral-A (RALA) ELISA kit; MGC48949; RAL; RAS-like protein A; Ras family small GTP binding protein RALA; Ras-related protein Ral-A; ras related v-ral simian leukemia viral oncogene homolog A; v-ral simian leukemia viral oncogene homolog A (ras related)
 Product Gene Name   

RALA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    179550
 3D Structure    ModBase 3D Structure for P11233
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RALA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RALA purchase    MBS9330319 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the v-ral simian leukemia viral oncogene homolog A (ras related) (RALA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RALA. The ELISA analytical biochemical technique of the MBS9330319 kit is based on RALA antibody-RALA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RALA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RALA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Sample Manual Insert of MBS9330319. Click to request current manual
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NCBI/Uniprot data below describe general gene information for RALA. It may not necessarily be applicable to this product.
 NCBI GI #    33946329
 NCBI GeneID    5898
 NCBI Accession #    NP_005393.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005402.3 [Other Products]
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 UniProt Primary Accession #    P11233 [Other Products]
 UniProt Secondary Accession #    A4D1W3 [Other Products]
 UniProt Related Accession #    P11233 [Other Products]
 Molecular Weight    23,567 Da
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 NCBI Official Full Name    ras-related protein Ral-A
 NCBI Official Synonym Full Names    v-ral simian leukemia viral oncogene homolog A (ras related)
 NCBI Official Symbol    RALA [Similar Products]
 NCBI Official Synonym Symbols   
RAL
[Similar Products]
 NCBI Protein Information    ras-related protein Ral-A; RAS-like protein A; ras related GTP binding protein A; Ras family small GTP binding protein RALA
 UniProt Protein Name    Ras-related protein Ral-A
 Protein Family    Ras-related protein
 UniProt Gene Name    RALA [Similar Products]
 UniProt Synonym Gene Names    RAL [Similar Products]
 UniProt Entry Name    RALA_HUMAN
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 NCBI Summary for RALA    The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins. [provided by RefSeq, Jul 2008]
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 UniProt Comments for RALA    RALA: Multifuntional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin- dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells. Interacts with RALBP1 via its effector domain. Interacts with EXOC8 and EXOC2. EXOC2 and EXOC8 have overlapping binding sites and compete for RALA binding. Interacts with Clostridium exoenzyme C3. Interacts with RALGPS1. Interacts with LPAR1 and LPAR2. Interacts with ADRBK1 in response to LPAR1 activation. RALA and ADRBK1 mutually inhibit each other's binding to LPAR1. Activated in an LPA-dependent manner by LPAR1 and in an LPA-independent manner by LPAR2. Alternate between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase- activating protein (GAP). Belongs to the small GTPase superfamily. Ras family.

Protein type: Motility/polarity/chemotaxis; G protein; G protein, monomeric; G protein, monomeric, Ras

Chromosomal Location of Human Ortholog: 7p15-p13

Cellular Component: cell surface; focal adhesion; cytoplasmic vesicle membrane; endocytic vesicle; plasma membrane; midbody; cleavage furrow

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; myosin binding; Edg-2 lysophosphatidic acid receptor binding; ubiquitin protein ligase binding; ATPase binding

Biological Process: positive regulation of filopodium formation; regulation of exocytosis; exocytosis; lipid raft localization; viral reproduction; nerve growth factor receptor signaling pathway; metabolic process; actin cytoskeleton reorganization; Ras protein signal transduction; cytokinesis; chemotaxis; signal transduction
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 Research Articles on RALA    1. Data show that small GTPase RALA regulates formation of a JIP1 (C-Jun-amino-terminal-interacting protein 1) scaffold complex to propagate JNK signaling toward FOXO4 (forkhead box O transcription factor) in response to reactive oxygen species (ROS).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RALA elisa kitPathways associated with RALA elisa kit
 Reference Product  PubMed Publications
 RALBP1 elisa kit  >29 publications with RALA and RALBP1
 PLD1 elisa kit  >11 publications with RALA and PLD1
 EXOC2 elisa kit  >10 publications with RALA and EXOC2
 EXOC8 elisa kit  >7 publications with RALA and EXOC8
 EXOC4 elisa kit  >3 publications with RALA and EXOC4
 EXOC3 elisa kit  >3 publications with RALA and EXOC3
 ARF1 elisa kit  >2 publications with RALA and ARF1
 PPP2R1B elisa kit  >1 publications with RALA and PPP2R1B
 CNKSR2 elisa kit  >1 publications with RALA and CNKSR2
 Products by Pathway  Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 ErbB1 Downstream Signaling Pathway antibodies  ErbB1 Downstream Signaling Pathway Diagram
 NGF Signalling Via TRKA From The Plasma Membrane Pathway antibodies  NGF Signalling Via TRKA From The Plasma Membrane Pathway Diagram
 Pancreatic Cancer Pathway antibodies  Pancreatic Cancer Pathway Diagram
 Pancreatic Cancer Pathway antibodies  Pancreatic Cancer Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signalling By NGF Pathway antibodies  Signalling By NGF Pathway Diagram
 Signalling To ERKs Pathway antibodies  Signalling To ERKs Pathway Diagram
 Signalling To RAS Pathway antibodies  Signalling To RAS Pathway Diagram
Diseases associated with RALA elisa kitOrgans/Tissues associated with RALA elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >66 publications with RALA and Neoplasms
 Carcinoma Antibodies  >26 publications with RALA and Carcinoma
 Cell Transformation, Neoplastic Antibodies  >24 publications with RALA and Cell Transformation, Neoplastic
 Neoplasm Metastasis Antibodies  >11 publications with RALA and Neoplasm Metastasis
 Urologic Neoplasms Antibodies  >9 publications with RALA and Urologic Neoplasms
 Necrosis Antibodies  >9 publications with RALA and Necrosis
 Urinary Bladder Neoplasms Antibodies  >8 publications with RALA and Urinary Bladder Neoplasms
 Adenocarcinoma Antibodies  >8 publications with RALA and Adenocarcinoma
 Leukemia Antibodies  >8 publications with RALA and Leukemia
 Pancreatic Neoplasms Antibodies  >8 publications with RALA and Pancreatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >24 publications with RALA and Blood
 Brain Antibodies  >23 publications with RALA and Brain
 Kidney Antibodies  >12 publications with RALA and Kidney
 Bladder Antibodies  >10 publications with RALA and Bladder
 Lung Antibodies  >10 publications with RALA and Lung
 Prostate Antibodies  >9 publications with RALA and Prostate
 Muscle Antibodies  >9 publications with RALA and Muscle
 Liver Antibodies  >9 publications with RALA and Liver
 Vascular Antibodies  >8 publications with RALA and Vascular
 Skin Antibodies  >7 publications with RALA and Skin
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