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| Product Name
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valyl-tRNA synthetase 2, mitochondrial (putative) (VARS2), ELISA Kit
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| Also Known As
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Human Valyl-tRNA synthetase, mitochondrial, VARS2 ELISA Kit
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| Product Synonym Names
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Human Valyl-tRNA synthetase; mitochondrial (VARS2) ELISA kit; DADB-160J14.3; MGC138259; MGC142165; VARS2L; VARSL; valine tRNA ligase 2; mitochondrial (putative) ; valyl-tRNA synthetase 2; mitochondrial; valyl-tRNA synthetase 2-like; valyl-tRNA synthetase like; valyl-tRNA synthetase 2; mitochondrial (putative)
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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| Request for Current Manual Insert
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| OMIM
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612802
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| 3D Structure
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ModBase 3D Structure for Q5ST30
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| Species Reactivity
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Human
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| Preparation and Storage
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Store all reagents at 2-8 degree C
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| Product Note
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Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
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| Other Notes
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Small volumes of VARS2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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| Searchable Terms for VARS2 purchase
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MBS9324553 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the valyl-tRNA synthetase 2, mitochondrial (putative) (VARS2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing VARS2. The ELISA analytical biochemical technique of the MBS9324553 kit is based on VARS2 antibody-VARS2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect VARS2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, VARS2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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| NCBI/Uniprot data below describe general gene information for VARS2. It may not necessarily be applicable to this product. |
| NCBI GI #
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268370295
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| NCBI GeneID
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57176
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| NCBI Accession #
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NP_001161205.1
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[Other Products]
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| NCBI GenBank Nucleotide #
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NM_001167733.2
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[Other Products]
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| UniProt Primary Accession #
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Q5ST30
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[Other Products]
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| UniProt Secondary Accession #
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Q2M2A0; Q59FI1; Q5SQ96; Q5SS98; Q6DKJ5; Q6ZV24; A2ABL7; B4DET4; B4E3P5; F5GXJ0; F5H323
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[Other Products]
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| UniProt Related Accession #
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Q5ST30
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[Other Products]
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| Molecular Weight
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118,490 Da
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| NCBI Official Full Name
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valine--tRNA ligase, mitochondrial isoform 3
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| NCBI Official Synonym Full Names
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valyl-tRNA synthetase 2, mitochondrial
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| NCBI Official Symbol
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VARS2
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[Similar Products]
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| NCBI Official Synonym Symbols
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VALRS; VARSL; VARS2L; COXPD20
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[Similar Products]
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| NCBI Protein Information
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valine--tRNA ligase, mitochondrial; valyl-tRNA synthetase like; valine tRNA ligase 2, mitochondrial (putative)
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| UniProt Protein Name
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Valine--tRNA ligase, mitochondrial
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| UniProt Synonym Protein Names
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Valyl-tRNA synthetase; ValRS; Valyl-tRNA synthetase-like
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| UniProt Gene Name
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VARS2
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[Similar Products]
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| UniProt Synonym Gene Names
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KIAA1885; VARS2L; VARSL; ValRS
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[Similar Products]
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| UniProt Entry Name
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SYVM_HUMAN
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| NCBI Summary for VARS2
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This gene encodes a mitochondrial aminoacyl-tRNA synthetase, which catalyzes the attachment of valine to tRNA(Val) for mitochondrial translation. Mutations in this gene cause combined oxidative phosphorylation deficiency-20, and are also associated with early-onset mitochondrial encephalopathies. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2014]
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| UniProt Comments for VARS2
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VARS2: Belongs to the class-I aminoacyl-tRNA synthetase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Ligase; Translation; EC 6.1.1.9
Chromosomal Location of Human Ortholog: 6p21.33
Cellular Component: mitochondrion; cytosol
Molecular Function: valine-tRNA ligase activity; ATP binding
Biological Process: tRNA aminoacylation for protein translation; regulation of translational fidelity; gene expression; valyl-tRNA aminoacylation
Disease: Combined Oxidative Phosphorylation Deficiency 20
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| Research Articles on VARS2
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1. VARS2 V552V may be considered as a prognostic factor for survival in patients with early breast cancer.
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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| Pathways associated with VARS2 elisa kit | Diseases associated with VARS2 elisa kit |
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| Organs/Tissues associated with VARS2 elisa kit |
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ELISA Kit 
