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VARS2 elisa kit :: Human valyl-tRNA synthetase 2, mitochondrial (putative) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9324553 VARS2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

valyl-tRNA synthetase 2, mitochondrial (putative) (VARS2), ELISA Kit

 Also Known As   

Human Valyl-tRNA synthetase, mitochondrial, VARS2 ELISA Kit

 Product Synonym Names    Human Valyl-tRNA synthetase; mitochondrial (VARS2) ELISA kit; DADB-160J14.3; MGC138259; MGC142165; VARS2L; VARSL; valine tRNA ligase 2; mitochondrial (putative) ; valyl-tRNA synthetase 2; mitochondrial; valyl-tRNA synthetase 2-like; valyl-tRNA synthetase like; valyl-tRNA synthetase 2; mitochondrial (putative)
 Product Gene Name   

VARS2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    612802
 3D Structure    ModBase 3D Structure for Q5ST30
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of VARS2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for VARS2 purchase    MBS9324553 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the valyl-tRNA synthetase 2, mitochondrial (putative) (VARS2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing VARS2. The ELISA analytical biochemical technique of the MBS9324553 kit is based on VARS2 antibody-VARS2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect VARS2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, VARS2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for VARS2. It may not necessarily be applicable to this product.
 NCBI GI #    268370295
 NCBI GeneID    57176
 NCBI Accession #    NP_001161205.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001167733.2 [Other Products]
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 UniProt Primary Accession #    Q5ST30 [Other Products]
 UniProt Secondary Accession #    Q2M2A0; Q59FI1; Q5SQ96; Q5SS98; Q6DKJ5; Q6ZV24; A2ABL7; B4DET4; B4E3P5; F5GXJ0; F5H323 [Other Products]
 UniProt Related Accession #    Q5ST30 [Other Products]
 Molecular Weight    118,490 Da
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 NCBI Official Full Name    valine--tRNA ligase, mitochondrial isoform 3
 NCBI Official Synonym Full Names    valyl-tRNA synthetase 2, mitochondrial
 NCBI Official Symbol    VARS2 [Similar Products]
 NCBI Official Synonym Symbols   
VALRS; VARSL; VARS2L; COXPD20
[Similar Products]
 NCBI Protein Information    valine--tRNA ligase, mitochondrial; valyl-tRNA synthetase like; valine tRNA ligase 2, mitochondrial (putative)
 UniProt Protein Name    Valine--tRNA ligase, mitochondrial
 UniProt Synonym Protein Names   
Valyl-tRNA synthetase; ValRS; Valyl-tRNA synthetase-like
 UniProt Gene Name    VARS2 [Similar Products]
 UniProt Synonym Gene Names    KIAA1885; VARS2L; VARSL; ValRS [Similar Products]
 UniProt Entry Name    SYVM_HUMAN
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 NCBI Summary for VARS2    This gene encodes a mitochondrial aminoacyl-tRNA synthetase, which catalyzes the attachment of valine to tRNA(Val) for mitochondrial translation. Mutations in this gene cause combined oxidative phosphorylation deficiency-20, and are also associated with early-onset mitochondrial encephalopathies. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2014]
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 UniProt Comments for VARS2    VARS2: Belongs to the class-I aminoacyl-tRNA synthetase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Ligase; Translation; EC 6.1.1.9

Chromosomal Location of Human Ortholog: 6p21.33

Cellular Component: mitochondrion; cytosol

Molecular Function: valine-tRNA ligase activity; ATP binding

Biological Process: tRNA aminoacylation for protein translation; regulation of translational fidelity; gene expression; valyl-tRNA aminoacylation

Disease: Combined Oxidative Phosphorylation Deficiency 20
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 Research Articles on VARS2    1. VARS2 V552V may be considered as a prognostic factor for survival in patients with early breast cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with VARS2 elisa kitDiseases associated with VARS2 elisa kit
 Products by Pathway  Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Mitochondrial TRNA Aminoacylation Pathway antibodies  Mitochondrial TRNA Aminoacylation Pathway Diagram
 TRNA Aminoacylation Pathway antibodies  TRNA Aminoacylation Pathway Diagram
 Disease Name  Pubmed Publications
 Muscular Diseases Antibodies  >1 publications with VARS2 and Muscular Diseases
 Breast Neoplasms Antibodies  >1 publications with VARS2 and Breast Neoplasms
 Skin Diseases Antibodies  >1 publications with VARS2 and Skin Diseases
 Nervous System Diseases Antibodies  >1 publications with VARS2 and Nervous System Diseases
 Drug Toxicity Antibodies  >1 publications with VARS2 and Drug Toxicity
 Drug-Induced Liver Injury Antibodies  >1 publications with VARS2 and Drug-Induced Liver Injury
Organs/Tissues associated with VARS2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with VARS2 and Lung
 Liver Antibodies  >1 publications with VARS2 and Liver
 Blood Antibodies  >1 publications with VARS2 and Blood
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