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VAV2 elisa kit :: Human vav 2 guanine nucleotide exchange factor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9335399 VAV2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

vav 2 guanine nucleotide exchange factor (VAV2), ELISA Kit

 Also Known As   

Human Guanine nucleotide exchange factor VAV2, VAV2 ELISA Kit

 Product Synonym Names    Human Guanine nucleotide exchange factor VAV2 (VAV2) ELISA kit; Protein vav-2; oncogene VAV2; vav 2 oncogene; vav 2 guanine nucleotide exchange factor
 Product Gene Name   

VAV2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    600428
 3D Structure    ModBase 3D Structure for P52735
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 Species Reactivity    Human
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 Samples    Serum, Plasma and Tissue Homogenate
 Assay Type    Sandwich
 Detection Range    62.5pg/ml-2000pg/ml.
 Sensitivity    10pg/ml.
 Intended Uses    This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of VAV2 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of VAV2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for VAV2 purchase    MBS9335399 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the vav 2 guanine nucleotide exchange factor (VAV2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5pg/ml-2000pg/ml in biological research samples containing VAV2, with an estimated sensitivity of 10pg/ml. The ELISA analytical biochemical technique of the MBS9335399 kit is based on VAV2 antibody-VAV2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect VAV2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, VAV2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma and Tissue Homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for VAV2 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of VAV2 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
Sample Manual Insert of MBS9335399. Click to request current manual
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NCBI/Uniprot data below describe general gene information for VAV2. It may not necessarily be applicable to this product.
 NCBI GI #    197304715
 NCBI GeneID    7410
 NCBI Accession #    NP_001127870.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001134398.1 [Other Products]
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 UniProt Primary Accession #    P52735 [Other Products]
 UniProt Secondary Accession #    Q5SYV3; Q5SYV4; Q5SYV5; Q6N012; Q6PIJ9; Q6Q317; A2RUM4; A8MQ12; B6ZDF5 [Other Products]
 UniProt Related Accession #    P52735 [Other Products]
 Molecular Weight    101,289 Da
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 NCBI Official Full Name    guanine nucleotide exchange factor VAV2 isoform 1
 NCBI Official Synonym Full Names    vav 2 guanine nucleotide exchange factor
 NCBI Official Symbol    VAV2 [Similar Products]
 NCBI Official Synonym Symbols   
VAV-2
[Similar Products]
 NCBI Protein Information    guanine nucleotide exchange factor VAV2; vav 2 oncogene
 UniProt Protein Name    Guanine nucleotide exchange factor VAV2
 Protein Family    Guanine nucleotide exchange factor
 UniProt Gene Name    VAV2 [Similar Products]
 UniProt Synonym Gene Names    VAV-2 [Similar Products]
 UniProt Entry Name    VAV2_HUMAN
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 NCBI Summary for VAV2    VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
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 UniProt Comments for VAV2    VAV2: a proto-oncogenic guanine nucleotide exchange factors (GEF) of the Dbl family. A GEF for the Rho family of GTP binding proteins. Expressed in most tissues.

Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: plasma membrane; cytosol

Molecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; metal ion binding; guanyl-nucleotide exchange factor activity; epidermal growth factor receptor binding

Biological Process: lamellipodium biogenesis; axon guidance; platelet activation; cell migration; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; positive regulation of phosphoinositide 3-kinase activity; signal transduction; regulation of small GTPase mediated signal transduction; regulation of gene expression; small GTPase mediated signal transduction; regulation of blood coagulation; ephrin receptor signaling pathway; innate immune response; angiogenesis; blood coagulation; vascular endothelial growth factor receptor signaling pathway
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 Research Articles on VAV2    1. Data suggest a coordination between paxillin kinase linker (PKL)/Vav2 signaling and PKL/beta-PIX signaling during cell migration.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with VAV2 elisa kitPathways associated with VAV2 elisa kit
 Reference Product  PubMed Publications
 RAC1 elisa kit  >55 publications with VAV2 and RAC1
 RHOA elisa kit  >45 publications with VAV2 and RHOA
 EGFR elisa kit  >11 publications with VAV2 and EGFR
 SYK elisa kit  >9 publications with VAV2 and SYK
 RHOG elisa kit  >5 publications with VAV2 and RHOG
 CBL elisa kit  >4 publications with VAV2 and CBL
 NEK3 elisa kit  >3 publications with VAV2 and NEK3
 GRB2 elisa kit  >2 publications with VAV2 and GRB2
 CD19 elisa kit  >2 publications with VAV2 and CD19
 SH3BP2 elisa kit  >1 publications with VAV2 and SH3BP2
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 CDC42 Signaling Events Pathway antibodies  CDC42 Signaling Events Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
Diseases associated with VAV2 elisa kit
 Disease Name  Pubmed Publications
 Cell Transformation, Neoplastic Antibodies  >7 publications with VAV2 and Cell Transformation, Neoplastic
 Inflammation Antibodies  >5 publications with VAV2 and Inflammation
 Lung Neoplasms Antibodies  >5 publications with VAV2 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >5 publications with VAV2 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >4 publications with VAV2 and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with VAV2 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with VAV2 and Carcinoma, Hepatocellular
 Weight Loss Antibodies  >2 publications with VAV2 and Weight Loss
 Kidney Diseases Antibodies  >2 publications with VAV2 and Kidney Diseases
 Edema Antibodies  >1 publications with VAV2 and Edema
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