NP_056151.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
72,640 Da
NCBI Official Full Name
palmitoyltransferase ZDHHC17
NCBI Official Synonym Full Names
zinc finger, DHHC-type containing 17
NCBI Protein Information
palmitoyltransferase ZDHHC17; HIP-3; HIP-14; DHHC-17; huntingtin yeast partner H; Huntingtin interacting protein H; huntingtin interacting protein 3; huntingtin-interacting protein 3; huntingtin-interacting protein H; huntingtin interacting protein 14; huntingtin-interacting protein 14; putative MAPK-activating protein PM11; zinc finger, DHHC domain containing 17; putative NF-kappa-B-activating protein 205; zinc finger DHHC domain-containing protein 17
UniProt Protein Name
Palmitoyltransferase ZDHHC17
UniProt Synonym Protein Names
Huntingtin yeast partner H; Huntingtin-interacting protein 14; HIP-14; Huntingtin-interacting protein 3; HIP-3; Huntingtin-interacting protein H; Putative MAPK-activating protein PM11; Putative NF-kappa-B-activating protein 205; Zinc finger DHHC domain-containing protein 17; DHHC-17
UniProt Synonym Gene Names
UniProt Entry Name
ZDH17_HUMAN
UniProt Comments for ZDHHC17
HIP14: a palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, PSD-95, GAD2, SYT1 and Huntingtin. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May be involved in the NF-kappa-B signaling pathway. Can cause cellular transformation, and is up-regulated in a number of types of human tumors. Expressed in all brain regions. Expression is highest in the cortex, cerebellum, occipital lobe and caudate, and lowest in the spinal cord. Expression is also seen in testis, pancreas, heart and kidney. Three alternatively spliced isoforms have been described.
Protein type: Membrane protein, multi-pass; EC 2.3.1.225; Transferase; Tumor suppressor; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q21.2
Cellular Component: Golgi membrane; Golgi apparatus; intracellular membrane-bound organelle; cytoplasm; integral to membrane
Molecular Function: identical protein binding; protein binding; signal transducer activity; zinc ion binding; palmitoyltransferase activity; magnesium ion transmembrane transporter activity; protein-cysteine S-palmitoleyltransferase activity
Biological Process: protein palmitoylation; positive regulation of I-kappaB kinase/NF-kappaB cascade; lipoprotein transport; signal transduction; magnesium ion transport
Research Articles on ZDHHC17
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Products associated with ZDHHC17 elisa kit
Diseases associated with ZDHHC17 elisa kit
Organs/Tissues associated with ZDHHC17 elisa kit
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