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ZFYVE9 elisa kit :: Human zinc finger, FYVE domain containing 9 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9322150 ZFYVE9 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

zinc finger, FYVE domain containing 9 (ZFYVE9), ELISA Kit

 Also Known As   

Human Zinc finger FYVE domain-containing protein 9, ZFYVE9 ELISA Kit

 Product Synonym Names    Human Zinc finger FYVE domain-containing protein 9 (ZFYVE9) ELISA kit; MADHIP; NSP; SARA; SMADIP; MAD homolog interacting protein; MAD; mothers against decapentaplegic homolog interacting protein; receptor activation anchor; MADH-interacting protein; OTTHUMP00000009739; mo; zinc finger; FYVE domain containing 9
 Product Gene Name   

ZFYVE9 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    603755
 3D Structure    ModBase 3D Structure for O95405
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ZFYVE9 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ZFYVE9 purchase    MBS9322150 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the zinc finger, FYVE domain containing 9 (ZFYVE9) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ZFYVE9. The ELISA analytical biochemical technique of the MBS9322150 kit is based on ZFYVE9 antibody-ZFYVE9 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ZFYVE9 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ZFYVE9. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ZFYVE9. It may not necessarily be applicable to this product.
 NCBI GI #    47717106
 NCBI GeneID    9372
 NCBI Accession #    NP_004790.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004799.3 [Other Products]
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 UniProt Primary Accession #    O95405 [Other Products]
 UniProt Secondary Accession #    Q5T0F6; Q5T0F7; Q9UNE1; Q9Y5R7 [Other Products]
 UniProt Related Accession #    O95405 [Other Products]
 Molecular Weight    156,403 Da
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 NCBI Official Full Name    zinc finger FYVE domain-containing protein 9 isoform 3
 NCBI Official Synonym Full Names    zinc finger, FYVE domain containing 9
 NCBI Official Symbol    ZFYVE9 [Similar Products]
 NCBI Official Synonym Symbols   
NSP; SARA; MADHIP; SMADIP; PPP1R173
[Similar Products]
 NCBI Protein Information    zinc finger FYVE domain-containing protein 9; novel serine protease; MADH-interacting protein; smad anchor for receptor activation; protein phosphatase 1, regulatory subunit 173; MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor
 UniProt Protein Name    Zinc finger FYVE domain-containing protein 9
 UniProt Synonym Protein Names   
Mothers against decapentaplegic homolog-interacting protein; Madh-interacting protein; Novel serine protease; NSP; Receptor activation anchor; hSARA; Smad anchor for receptor activation
 Protein Family    Zinc finger FYVE domain-containing protein
 UniProt Gene Name    ZFYVE9 [Similar Products]
 UniProt Synonym Gene Names    MADHIP; SARA; SMADIP; Madh-interacting protein; NSP; hSARA [Similar Products]
 UniProt Entry Name    ZFYV9_HUMAN
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 NCBI Summary for ZFYVE9    This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
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 UniProt Comments for ZFYVE9    SARA: Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1p32.3

Cellular Component: early endosome membrane; early endosome

Molecular Function: protein binding; serine-type peptidase activity; metal ion binding; phosphatidylinositol binding

Biological Process: transforming growth factor beta receptor signaling pathway; endocytosis; SMAD protein nuclear translocation; negative regulation of transforming growth factor beta receptor signaling pathway; proteolysis; SMAD protein complex assembly
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 Research Articles on ZFYVE9    1. The negative influence that perturbation of RNF11 and SARA levels exerts on the lysosomal degradation of EGFRs could underscore the significance of overexpression of RNF11 in certain cancers.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ZFYVE9 elisa kitOrgans/Tissues associated with ZFYVE9 elisa kit
 Products by Pathway  Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By TGF Beta Pathway antibodies  Signaling By TGF Beta Pathway Diagram
 TGF Beta Signaling Pathway antibodies  TGF Beta Signaling Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >1 publications with ZFYVE9 and Testis
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