NP_722520.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
104,888 Da
NCBI Official Full Name
zinc finger protein ZFPM1
NCBI Official Synonym Full Names
zinc finger protein, FOG family member 1
NCBI Official Synonym Symbols
FOG; FOG1; ZNF408; ZNF89A; ZC2HC11A [Similar Products]
NCBI Protein Information
zinc finger protein ZFPM1; FOG-1; friend of GATA 1; friend of GATA-1; zinc finger protein 89A; friend of GATA protein 1; zinc finger protein, multitype 1
UniProt Protein Name
Zinc finger protein ZFPM1
UniProt Synonym Protein Names
Friend of GATA protein 1; FOG-1; Friend of GATA 1; Zinc finger protein 89A; Zinc finger protein multitype 1
UniProt Synonym Gene Names
UniProt Entry Name
FOG1_HUMAN
UniProt Comments for ZFPM1
FOG1: Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2. Belongs to the FOG (Friend of GATA) family.
Protein type: C2H2-type zinc finger protein; Transcription regulation
Chromosomal Location of Human Ortholog: 16q24.2
Cellular Component: nucleoplasm; transcription factor complex; transcriptional repressor complex; cytoplasm; nucleus
Molecular Function: protein binding; DNA binding; metal ion binding; transcription factor binding
Biological Process: granulocyte differentiation; transcription, DNA-dependent; megakaryocyte differentiation; embryonic hemopoiesis; heart development; T-helper cell lineage commitment; negative regulation of transcription from RNA polymerase II promoter; negative regulation of fat cell differentiation; negative regulation of interleukin-4 biosynthetic process; cardiac muscle morphogensis; erythrocyte differentiation; platelet formation; negative regulation of protein binding; blood coagulation; regulation of chemokine production; positive regulation of interferon-gamma biosynthetic process
Research Articles on ZFPM1
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Products associated with ZFPM1 elisa kit
Pathways associated with ZFPM1 elisa kit
Diseases associated with ZFPM1 elisa kit
Organs/Tissues associated with ZFPM1 elisa kit
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