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ZFPM2 elisa kit :: Human zinc finger protein, multitype 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9335069 ZFPM2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

zinc finger protein, multitype 2 (ZFPM2), ELISA Kit

 Also Known As   

Human Zinc finger protein ZFPM2, ZFPM2 ELISA Kit

 Product Synonym Names    Human Zinc finger protein ZFPM2 (ZFPM2) ELISA kit; DIH3; FOG2; MGC129663; MGC129664; ZNF89B; hFOG-2; Friend of GATA2; transcription factor GATA4; modulator of; zinc finger protein; multitype 2
 Product Gene Name   

ZFPM2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 610187
 3D Structure    ModBase 3D Structure for Q8WW38
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ZFPM2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ZFPM2 purchase    MBS9335069 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the zinc finger protein, multitype 2 (ZFPM2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ZFPM2. The ELISA analytical biochemical technique of the MBS9335069 kit is based on ZFPM2 antibody-ZFPM2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ZFPM2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ZFPM2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ZFPM2. It may not necessarily be applicable to this product.
 NCBI GI #    223890230
 NCBI GeneID    23414
 NCBI Accession #    NP_036214.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_012082.3 [Other Products]
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 UniProt Primary Accession #    Q8WW38 [Other Products]
 UniProt Secondary Accession #    Q32MA6; Q9NPL7; Q9NPS4; Q9UNI5 [Other Products]
 UniProt Related Accession #    Q8WW38 [Other Products]
 Molecular Weight    128,159 Da
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 NCBI Official Full Name    zinc finger protein ZFPM2
 NCBI Official Synonym Full Names    zinc finger protein, FOG family member 2
 NCBI Official Symbol    ZFPM2 [Similar Products]
 NCBI Official Synonym Symbols   
DIH3; FOG2; ZNF89B; hFOG-2; ZC2HC11B
[Similar Products]
 NCBI Protein Information    zinc finger protein ZFPM2; FOG-2; Friend of GATA2; friend of GATA 2; zinc finger protein 89B; friend of GATA protein 2; zinc finger protein, multitype 2; transcription factor GATA4, modulator of
 UniProt Protein Name    Zinc finger protein ZFPM2
 UniProt Synonym Protein Names   
Friend of GATA protein 2; FOG-2; Friend of GATA 2; hFOG-2; Zinc finger protein 89B; Zinc finger protein multitype 2
 Protein Family    Zinc finger protein
 UniProt Gene Name    ZFPM2 [Similar Products]
 UniProt Synonym Gene Names    FOG2; ZNF89B; FOG-2; Friend of GATA 2; hFOG-2 [Similar Products]
 UniProt Entry Name    FOG2_HUMAN
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 NCBI Summary for ZFPM2    The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ZFPM2    FOG2: Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2. Defects in ZFPM2 may be a cause of tetralogy of Fallot (TOF). TOF is a congenital heart anomaly which consists of pulmonary stenosis, ventricular septal defect, dextroposition of the aorta (aorta is on the right side instead of the left) and hypertrophy of the right ventricle. This condition results in a blue baby at birth due to inadequate oxygenation. Surgical correction is emergent. Defects in ZFPM2 are the cause of diaphragmatic hernia 3 (DIH3); a form of congenital diaphragmatic hernia (CDH). CDH refers to a group of congenital defects in the structural integrity of the diaphragm associated with often lethal pulmonary hypoplasia and pulmonary hypertension. Belongs to the FOG (Friend of GATA) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 8q23

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding; DNA binding; zinc ion binding; transcription corepressor activity; transcription factor binding

Biological Process: transcription, DNA-dependent; in utero embryonic development; embryonic organ development; gonadal mesoderm development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; blood coagulation; negative regulation of transcription, DNA-dependent; vasculogenesis; negative regulation of fat cell differentiation; lung development

Disease: Tetralogy Of Fallot; 46,xy Sex Reversal 9; Diaphragmatic Hernia 3
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 Research Articles on ZFPM2    1. FOG1, FOG2 and GATA-6 modulate the transcriptional up-regulation of HAMP in hepatocytes during inflammation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ZFPM2 elisa kitPathways associated with ZFPM2 elisa kit
 Reference Product  PubMed Publications
 GATA4 elisa kit  >46 publications with ZFPM2 and GATA4
 ZFPM1 elisa kit  >9 publications with ZFPM2 and ZFPM1
 GATA1 elisa kit  >7 publications with ZFPM2 and GATA1
 GATA6 elisa kit  >6 publications with ZFPM2 and GATA6
 GATA2 elisa kit  >5 publications with ZFPM2 and GATA2
 GATA3 elisa kit  >4 publications with ZFPM2 and GATA3
 AMH elisa kit  >3 publications with ZFPM2 and AMH
 CTBP2 elisa kit  >2 publications with ZFPM2 and CTBP2
 Products by Pathway  Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
Diseases associated with ZFPM2 elisa kitOrgans/Tissues associated with ZFPM2 elisa kit
 Disease Name  Pubmed Publications
 Hernia, Diaphragmatic Antibodies  >11 publications with ZFPM2 and Hernia, Diaphragmatic
 Tetralogy of Fallot Antibodies  >9 publications with ZFPM2 and Tetralogy of Fallot
 Diaphragmatic Hernia 3 Antibodies  >4 publications with ZFPM2 and Diaphragmatic Hernia 3
 Nervous System Diseases Antibodies  >3 publications with ZFPM2 and Nervous System Diseases
 Abnormalities, Multiple Antibodies  >3 publications with ZFPM2 and Abnormalities, Multiple
 Kidney Diseases Antibodies  >2 publications with ZFPM2 and Kidney Diseases
 Ovarian Neoplasms Antibodies  >2 publications with ZFPM2 and Ovarian Neoplasms
 Brain Diseases Antibodies  >2 publications with ZFPM2 and Brain Diseases
 Fibrosis Antibodies  >2 publications with ZFPM2 and Fibrosis
 Neurobehavioral Manifestations Antibodies  >2 publications with ZFPM2 and Neurobehavioral Manifestations
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >30 publications with ZFPM2 and Heart
 Testis Antibodies  >18 publications with ZFPM2 and Testis
 Embryonic Tissue Antibodies  >15 publications with ZFPM2 and Embryonic Tissue
 Muscle Antibodies  >14 publications with ZFPM2 and Muscle
 Ovary Antibodies  >9 publications with ZFPM2 and Ovary
 Vascular Antibodies  >7 publications with ZFPM2 and Vascular
 Lung Antibodies  >6 publications with ZFPM2 and Lung
 Brain Antibodies  >5 publications with ZFPM2 and Brain
 Liver Antibodies  >3 publications with ZFPM2 and Liver
 Skin Antibodies  >1 publications with ZFPM2 and Skin
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