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PSMD2 elisa kit :: Monkey 26S proteasome non-ATPase regulatory subunit 2 (PSMD2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7243736 PSMD2 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

26S proteasome non-ATPase regulatory subunit 2 (PSMD2), ELISA Kit

 Also Known As   

Monkey 26S proteasome non-ATPase regulatory subunit 2 (PSMD2) ELISA Kit

 Product Gene Name   

PSMD2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    606223
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 Species Reactivity    Monkey
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of PSMD2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PSMD2 purchase    MBS7243736 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 26S proteasome non-ATPase regulatory subunit 2 (PSMD2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PSMD2. The ELISA analytical biochemical technique of the MBS7243736 kit is based on PSMD2 antibody-PSMD2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PSMD2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PSMD2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for PSMD2 elisa kit    Cell Biology
NCBI/Uniprot data below describe general gene information for PSMD2. It may not necessarily be applicable to this product.
 NCBI GI #    523425734
 NCBI GeneID    5708
 NCBI Accession #    NP_001265637.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001278708.1 [Other Products]
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 UniProt Secondary Accession #    Q12932; Q15321; Q53XQ4; Q96I12; B4DX07; B4DXY1; E7EW34; E9PCS3 [Other Products]
 UniProt Related Accession #    Q13200 [Other Products]
 Molecular Weight    85,606 Da
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 NCBI Official Full Name    26S proteasome non-ATPase regulatory subunit 2 isoform 2
 NCBI Official Synonym Full Names    proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
 NCBI Official Symbol    PSMD2 [Similar Products]
 NCBI Official Synonym Symbols   
S2; P97; RPN1; TRAP2
[Similar Products]
 NCBI Protein Information    26S proteasome non-ATPase regulatory subunit 2; 55.11 protein; protein 55.11; TNFR-associated protein 2; tumor necrosis factor type 1 receptor-associated protein 2
 UniProt Protein Name    26S proteasome non-ATPase regulatory subunit 2
 UniProt Synonym Protein Names   
26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; Protein 55.11; Tumor necrosis factor type 1 receptor-associated protein 2
 Protein Family    26S proteasome non-ATPase regulatory
 UniProt Gene Name    PSMD2 [Similar Products]
 UniProt Synonym Gene Names    TRAP2 [Similar Products]
 UniProt Entry Name    PSMD2_HUMAN
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 NCBI Summary for PSMD2    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
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 UniProt Comments for PSMD2    PSMD2: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Belongs to the proteasome subunit S2 family.

Protein type: Cell cycle regulation; Proteasome complex

Chromosomal Location of Human Ortholog: 3q27.1

Cellular Component: nucleoplasm; proteasome complex; membrane; proteasome regulatory particle; cytosol

Molecular Function: protein binding; enzyme regulator activity

Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; protein polyubiquitination; viral reproduction; apoptosis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of apoptosis; antigen processing and presentation of peptide antigen via MHC class I; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; gene expression; mitotic cell cycle; regulation of amino acid metabolic process; negative regulation of apoptosis; G1/S transition of mitotic cell cycle
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 Research Articles on PSMD2    1. the high-resolution solution structure of the UBL domain of human UBLCP1 and its interaction with Rpn1
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PSMD2 elisa kitPathways associated with PSMD2 elisa kit
 Reference Product  PubMed Publications
 PSMD1 elisa kit  >2 publications with PSMD2 and PSMD1
 PSMC2 elisa kit  >2 publications with PSMD2 and PSMC2
 PSMD5 elisa kit  >1 publications with PSMD2 and PSMD5
 PSMC1 elisa kit  >1 publications with PSMD2 and PSMC1
 PSMC5 elisa kit  >1 publications with PSMD2 and PSMC5
 Products by Pathway  Pathway Diagram
 AMER1 Mutants Destabilize The Destruction Complex Pathway antibodies  AMER1 Mutants Destabilize The Destruction Complex Pathway Diagram
 APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway antibodies  APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway Diagram
 APC Truncation Mutants Have Impaired AXIN Binding Pathway antibodies  APC Truncation Mutants Have Impaired AXIN Binding Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies  APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
 AUF1 (hnRNP D0) Destabilizes MRNA Pathway antibodies  AUF1 (hnRNP D0) Destabilizes MRNA Pathway Diagram
 AXIN Missense Mutants Destabilize The Destruction Complex Pathway antibodies  AXIN Missense Mutants Destabilize The Destruction Complex Pathway Diagram
 AXIN Mutants Destabilize The Destruction Complex, Activating WNT Signaling Pathway antibodies  AXIN Mutants Destabilize The Destruction Complex, Activating WNT Signaling Pathway Diagram
Diseases associated with PSMD2 elisa kitOrgans/Tissues associated with PSMD2 elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >19 publications with PSMD2 and Necrosis
 Death Antibodies  >3 publications with PSMD2 and Death
 Heart Diseases Antibodies  >1 publications with PSMD2 and Heart Diseases
 Fibrosis Antibodies  >1 publications with PSMD2 and Fibrosis
 Inflammation Antibodies  >1 publications with PSMD2 and Inflammation
 Atrophy Antibodies  >1 publications with PSMD2 and Atrophy
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with PSMD2 and Lung
 Blood Antibodies  >2 publications with PSMD2 and Blood
 Muscle Antibodies  >2 publications with PSMD2 and Muscle
 Nerve Antibodies  >1 publications with PSMD2 and Nerve
 Vascular Antibodies  >1 publications with PSMD2 and Vascular
 Heart Antibodies  >1 publications with PSMD2 and Heart
 Skin Antibodies  >1 publications with PSMD2 and Skin
 Brain Antibodies  >1 publications with PSMD2 and Brain
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