NP_001020241.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,273 Da
NCBI Official Full Name
40S ribosomal protein S14
NCBI Official Synonym Full Names
ribosomal protein S14
NCBI Official Synonym Symbols
NCBI Protein Information
40S ribosomal protein S14; emetine resistance
UniProt Protein Name
40S ribosomal protein S14
UniProt Synonym Gene Names
UniProt Entry Name
RS14_HUMAN
NCBI Summary for RPS14
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for RPS14
RPS14: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Protein type: RNA-binding; Ribosomal; Translation
Chromosomal Location of Human Ortholog: 5q31-q33
Cellular Component: focal adhesion; mitochondrion; membrane; cytoplasm; nucleolus; cytosol
Molecular Function: structural constituent of ribosome; RNA binding; translation regulator activity; mRNA 5'-UTR binding
Biological Process: SRP-dependent cotranslational protein targeting to membrane; viral reproduction; translation; translational termination; viral infectious cycle; negative regulation of transcription from RNA polymerase II promoter; maturation of SSU-rRNA; regulation of translation; translational elongation; cellular protein metabolic process; translational initiation; mRNA catabolic process, nonsense-mediated decay; ribosomal small subunit assembly and maintenance; erythrocyte differentiation; gene expression; viral transcription
Disease: Chromosome 5q Deletion Syndrome
Research Articles on RPS14
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Products associated with RPS14 elisa kit
Pathways associated with RPS14 elisa kit
Diseases associated with RPS14 elisa kit
Organs/Tissues associated with RPS14 elisa kit
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