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AP2M1 elisa kit :: Monkey AP-2 complex subunit mu (AP2M1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7218946 AP2M1 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AP-2 complex subunit mu (AP2M1), ELISA Kit

 Also Known As   

Monkey AP-2 complex subunit mu (AP2M1) ELISA Kit

 Product Gene Name   

AP2M1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    601024
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 Species Reactivity    Monkey
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    0.5-10ng/mL
 Sensitivity    0.1ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AP2M1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AP2M1 purchase    MBS7218946 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the AP-2 complex subunit mu (AP2M1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.5-10ng/mL in biological research samples containing AP2M1, with an estimated sensitivity of 0.1ng/mL. The ELISA analytical biochemical technique of the MBS7218946 kit is based on AP2M1 antibody-AP2M1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AP2M1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AP2M1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AP2M1. It may not necessarily be applicable to this product.
 NCBI GI #    14917109
 NCBI GeneID    1173
 NCBI Accession #    NP_004059.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004068.3 [Other Products]
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 UniProt Secondary Accession #    P20172; P53679; A6NE12; D3DNT1 [Other Products]
 UniProt Related Accession #    Q96CW1 [Other Products]
 Molecular Weight    49,389 Da [Similar Products]
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 NCBI Official Full Name    AP-2 complex subunit mu isoform a
 NCBI Official Synonym Full Names    adaptor-related protein complex 2, mu 1 subunit
 NCBI Official Symbol    AP2M1 [Similar Products]
 NCBI Official Synonym Symbols   
mu2; AP50; CLAPM1
[Similar Products]
 NCBI Protein Information    AP-2 complex subunit mu; adaptin-mu2; AP-2 mu chain; AP-2 mu 2 chain; HA2 50 kDA subunit; clathrin coat adaptor protein AP50; clathrin coat assembly protein AP50; clathrin coat-associated protein AP50; adaptor protein complex AP-2 subunit mu; clathrin adaptor complex AP2, mu subunit; plasma membrane adaptor AP-2 50kDA protein; plasma membrane adaptor AP-2 50 kDa protein; adapter-related protein complex 2 mu subunit; adapter-related protein complex 2 subunit mu; adaptor-related protein complex 2 subunit mu; clathrin assembly protein complex 2 medium chain; clathrin assembly protein complex 2 mu medium chain; clathrin-associated/assembly/adaptor protein, medium 1
 UniProt Protein Name    AP-2 complex subunit mu
 UniProt Synonym Protein Names   
AP-2 mu chain; Adaptin-mu2; Adaptor protein complex AP-2 subunit mu; Adaptor-related protein complex 2 subunit mu; Clathrin assembly protein complex 2 mu medium chain; Clathrin coat assembly protein AP50; Clathrin coat-associated protein AP50; HA2 50 kDa subunit; Plasma membrane adaptor AP-2 50 kDa protein
 UniProt Gene Name    AP2M1 [Similar Products]
 UniProt Synonym Gene Names    CLAPM1; KIAA0109 [Similar Products]
 UniProt Entry Name    AP2M1_HUMAN
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 NCBI Summary for AP2M1    This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AP2M1    AP2M1: a protein of the adaptor complexes medium subunit family. A subunit of the heterotetrameric coat assembly protein complex 2 (AP2) which links clathrin to receptors in coated vesicles. Interacts with the cytoplasmic tails of membrane proteins and polyphosphoinositide-containing lipids. Is not required for clathrin-coated vesicle formation at the plasma membrane, but that it is one of several endocytic adaptors required for the uptake of certain cargo proteins. Is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP-2 is a heterotetramer composed of two large chains (alpha and beta), a medium chain (AP50) and a small chain (AP17).

Protein type: Vesicle; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 3q28

Cellular Component: mitochondrion; lysosomal membrane; plasma membrane; AP-2 adaptor complex; cytosol

Molecular Function: protein binding; low-density lipoprotein receptor binding; transporter activity; signal sequence binding; lipid binding

Biological Process: negative regulation of epidermal growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway; axon guidance; synaptic transmission; intracellular protein transport; viral reproduction; nerve growth factor receptor signaling pathway; ephrin receptor signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class II; regulation of defense response to virus by virus
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 Research Articles on AP2M1    1. BMCC1 is an AP-2 associated endosomal protein in prostate cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AP2M1 elisa kitDiseases associated with AP2M1 elisa kit
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Arf1 Pathway antibodies  Arf1 Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 EGFR Downregulation Pathway antibodies  EGFR Downregulation Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies  EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >1 publications with AP2M1 and Fibrosis
 Hepatitis Antibodies  >1 publications with AP2M1 and Hepatitis
 Liver Diseases Antibodies  >1 publications with AP2M1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with AP2M1 and Carcinoma, Hepatocellular
Organs/Tissues associated with AP2M1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >1 publications with AP2M1 and Heart
 Pancreas Antibodies  >1 publications with AP2M1 and Pancreas
 Liver Antibodies  >1 publications with AP2M1 and Liver
 Brain Antibodies  >1 publications with AP2M1 and Brain
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