NP_443188.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,538 Da
NCBI Official Full Name
acyl-coenzyme A synthetase ACSM1, mitochondrial
NCBI Official Synonym Full Names
acyl-CoA synthetase medium-chain family member 1
NCBI Official Synonym Symbols
NCBI Protein Information
acyl-coenzyme A synthetase ACSM1, mitochondrial; Butyrate CoA ligase; butyrate--CoA ligase 1; lipoate-activating enzyme; butyryl Coenzyme A synthetase 1; butyryl-coenzyme A synthetase 1; medium-chain acyl-CoA synthetase; middle-chain acyl-CoA synthetase 1
UniProt Protein Name
Acyl-coenzyme A synthetase ACSM1, mitochondrial
UniProt Synonym Protein Names
Acyl-CoA synthetase medium-chain family member 1; Butyrate--CoA ligase 1; Butyryl-coenzyme A synthetase 1; Lipoate-activating enzyme; Middle-chain acyl-CoA synthetase 1
UniProt Synonym Gene Names
UniProt Entry Name
ACSM1_HUMAN
UniProt Comments for ACSM1
ACSM1: Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro). Functions as GTP-dependent lipoate- activating enzyme that generates the substrate for lipoyltransferase. Belongs to the ATP-dependent AMP-binding enzyme family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ligase; Mitochondrial; EC 6.2.1.2; Carbohydrate Metabolism - butanoate
Chromosomal Location of Human Ortholog: 16p12.3
Cellular Component: mitochondrial matrix
Molecular Function: acyl-CoA ligase activity; butyrate-CoA ligase activity; GTP binding; fatty-acid ligase activity; metal ion binding; ATP binding
Biological Process: cholesterol homeostasis; xenobiotic metabolic process; fatty acid oxidation; benzoate metabolic process; butyrate metabolic process; fatty acid biosynthetic process; energy derivation by oxidation of organic compounds
Research Articles on ACSM1
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Pathways associated with ACSM1 elisa kit
Diseases associated with ACSM1 elisa kit
Organs/Tissues associated with ACSM1 elisa kit
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