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BMP-7 elisa kit :: Monkey BMP-7 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2512665 BMP-7 elisa kit
Unit / Price
48-Strip-Wells  /  $400 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,975 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,480 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BMP-7, ELISA Kit

 Also Known As   

Monkey BMP-7 (Bone Morphogenetic Protein 7) ELISA Kit

 Product Gene Name   

BMP-7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    112267
 3D Structure    ModBase 3D Structure for P18075
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 Species Reactivity    Monkey
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 Specificity    This kit recognizes natural and recombinant Monkey BMP-7. No significant cross-reactivity or interference between Monkey BMP-7 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    31.25-2000pg/mL
 Sensitivity    18.75pg/mL
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 Preparation and Storage    Store at 4 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of BMP-7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMP-7 purchase    MBS2512665 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the BMP-7, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.25-2000pg/mL in biological research samples containing BMP-7, with an estimated sensitivity of 18.75pg/mL. The ELISA analytical biochemical technique of the MBS2512665 kit is based on BMP-7 antibody-BMP-7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP-7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP-7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for BMP-7 elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Monkey BMP-7 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to BMP-7. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for BMP-7 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain BMP-7, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of BMP-7. You can calculate the concentration of BMP-7 in the samples by comparing the OD of the samples to the standard curve.
Sample Manual Insert of MBS2512665
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NCBI/Uniprot data below describe general gene information for BMP-7. It may not necessarily be applicable to this product.
 NCBI GI #    4502427
 NCBI GeneID    655
 NCBI Accession #    NP_001710.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001719.2 [Other Products]
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 UniProt Primary Accession #    P18075 [Other Products]
 UniProt Secondary Accession #    Q9H512; Q9NTQ7 [Other Products]
 UniProt Related Accession #    P18075 [Other Products]
 Molecular Weight    49,313 Da
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 NCBI Official Full Name    bone morphogenetic protein 7
 NCBI Official Synonym Full Names    bone morphogenetic protein 7
 NCBI Official Symbol    BMP7 [Similar Products]
 NCBI Official Synonym Symbols   
OP-1
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 7; osteogenic protein 1
 UniProt Protein Name    Bone morphogenetic protein 7
 UniProt Synonym Protein Names   
Osteogenic protein 1; OP-1; INN: Eptotermin alfa
 UniProt Gene Name    BMP7 [Similar Products]
 UniProt Synonym Gene Names    OP1; BMP-7; OP-1 [Similar Products]
 UniProt Entry Name    BMP7_HUMAN
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 NCBI Summary for BMP-7    The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BMP-7    BMP7: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1. Expressed in the kidney and bladder. Lower levels seen in the brain. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20q13

Cellular Component: extracellular matrix; extracellular space; extracellular region

Molecular Function: heparin binding; protein binding; growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: axon guidance; response to peptide hormone stimulus; negative regulation of MAP kinase activity; extracellular matrix organization and biogenesis; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; negative regulation of NF-kappaB import into nucleus; embryonic pattern specification; response to estradiol stimulus; negative regulation of cell cycle; BMP signaling pathway; regulation of apoptosis; response to vitamin D; epithelial cell differentiation; ureteric bud development; dendrite development; mesonephros development; skeletal development; embryonic limb morphogenesis; ossification; positive regulation of heterotypic cell-cell adhesion; positive regulation of bone mineralization; odontogenesis of dentine-containing teeth; positive regulation of osteoblast differentiation; negative regulation of neuron differentiation; mesenchymal cell differentiation; branching morphogenesis of a tube; mesoderm formation; inhibition of NF-kappaB transcription factor; cartilage development; negative regulation of mitosis; negative regulation of phosphorylation; epithelial to mesenchymal transition; negative regulation of Notch signaling pathway; positive regulation of transcription from RNA polymerase II promoter; steroid hormone mediated signaling; embryonic camera-type eye morphogenesis; negative regulation of transcription, DNA-dependent; metanephros development; neurite morphogenesis; growth
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 Research Articles on BMP-7    1. BMP-7 may play anti-inflammatory and anti-fibrogenic roles in the pathogenesis of chronic hepatitis B infection.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BMP-7 elisa kitPathways associated with BMP-7 elisa kit
 Reference Product  PubMed Publications
 BMPR2 elisa kit  >118 publications with BMP-7 and BMPR2
 BMPR1A elisa kit  >75 publications with BMP-7 and BMPR1A
 SMAD5 elisa kit  >43 publications with BMP-7 and SMAD5
 BMPR1B elisa kit  >24 publications with BMP-7 and BMPR1B
 ACVR1 elisa kit  >24 publications with BMP-7 and ACVR1
 ACVR2A elisa kit  >6 publications with BMP-7 and ACVR2A
 SOSTDC1 elisa kit  >4 publications with BMP-7 and SOSTDC1
 NOG elisa kit  >4 publications with BMP-7 and NOG
 FST elisa kit  >3 publications with BMP-7 and FST
 CHRD elisa kit  >2 publications with BMP-7 and CHRD
 Products by Pathway  Pathway Diagram
 ALK2 Signaling Events Pathway antibodies  ALK2 Signaling Events Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
Diseases associated with BMP-7 elisa kitOrgans/Tissues associated with BMP-7 elisa kit
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >104 publications with BMP-7 and Fibrosis
 Disease Models, Animal Antibodies  >102 publications with BMP-7 and Disease Models, Animal
 Kidney Diseases Antibodies  >97 publications with BMP-7 and Kidney Diseases
 Cardiovascular Diseases Antibodies  >50 publications with BMP-7 and Cardiovascular Diseases
 Inflammation Antibodies  >50 publications with BMP-7 and Inflammation
 Necrosis Antibodies  >35 publications with BMP-7 and Necrosis
 Bone Resorption Antibodies  >35 publications with BMP-7 and Bone Resorption
 Renal Insufficiency Antibodies  >34 publications with BMP-7 and Renal Insufficiency
 Hypertension Antibodies  >33 publications with BMP-7 and Hypertension
 Prostatic Neoplasms Antibodies  >27 publications with BMP-7 and Prostatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1350 publications with BMP-7 and Bone
 Kidney Antibodies  >209 publications with BMP-7 and Kidney
 Embryonic Tissue Antibodies  >172 publications with BMP-7 and Embryonic Tissue
 Connective Tissue Antibodies  >158 publications with BMP-7 and Connective Tissue
 Muscle Antibodies  >111 publications with BMP-7 and Muscle
 Brain Antibodies  >109 publications with BMP-7 and Brain
 Mouth Antibodies  >88 publications with BMP-7 and Mouth
 Eye Antibodies  >71 publications with BMP-7 and Eye
 Prostate Antibodies  >39 publications with BMP-7 and Prostate
 Heart Antibodies  >38 publications with BMP-7 and Heart
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