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C-JUN elisa kit :: Monkey C-Jun ELISA Kit

Scan QR to view Datasheet Catalog #    MBS019143 C-JUN elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-Jun, ELISA Kit

 Also Known As   

Monkey C-Jun ELISA Kit

 Product Gene Name   

C-JUN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 6; NC_010448.3 (141231122..141232332). Location: chromosome: 6
 3D Structure    ModBase 3D Structure for P56432
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 Species Reactivity    Monkey
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of C-JUN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for C-JUN purchase    MBS019143 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-Jun, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing C-JUN. The ELISA analytical biochemical technique of the MBS019143 kit is based on C-JUN antibody-C-JUN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect C-JUN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, C-JUN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for C-JUN. It may not necessarily be applicable to this product.
 NCBI GI #    1911701
 NCBI GeneID    396913
 NCBI Accession #    AAB50808.1 [Other Products]
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 UniProt Primary Accession #    P56432 [Other Products]
 UniProt Related Accession #    P56432 [Other Products]
 Molecular Weight    35,629 Da
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 NCBI Official Full Name    c-Jun
 NCBI Official Symbol    C-JUN [Similar Products]
 NCBI Official Synonym Symbols   
Jun
[Similar Products]
 NCBI Protein Information    transcription factor AP-1; AP1; activator protein 1; proto-oncogene c-jun; V-jun avian sarcoma virus 17 oncogene homolog
 UniProt Protein Name    Transcription factor AP-1
 UniProt Synonym Protein Names   
Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog
 Protein Family    C-Jun-amino-terminal kinase-interacting protein
 UniProt Gene Name    JUN [Similar Products]
 UniProt Synonym Gene Names    AP1 [Similar Products]
 UniProt Entry Name    JUN_PIG
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 UniProt Comments for C-JUN    Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation

By similarity.

Subunit structure: Heterodimer with either FOS or BATF3 or ATF7

By similarity. The ATF7/JUN heterodimer is essential for ATF7 transactivation activity. Interacts with MYBBP1A, SP1, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with HIVEP3. Component of the SMAD3/SMAD4/JUN/FOS/complex which forms at the AP1 promoter site. The SMAD3/SMAD4 heterodimer acts syngernistically with the JUN/FOS heterodimer to activate transcription in response to TGF-beta. Interacts (via its basic DNA binding and leucine zipper domains) with SMAD3 (via an N-terminal domain); the interaction is required for TGF-beta-mediated transactivation of the SMAD3/SMAD4/JUN/FOS/complex

By similarity. Interacts with RNF187 and HIPK3

By similarity.

Subcellular location: Nucleus

By similarity.

Post-translational modification: Phosphorylated by CaMK4 and PRKDC; phosphorylation enhances the transcriptional activity. Phosphorylated by HIPK3. Phosphorylated by DYRK2 at Ser-243; this primes the protein for subsequent phosphorylation by GSK3B at Thr-239. Phosphorylated at Thr-239, Ser-243 and Ser-249 by GSK3B; phosphorylation reduces its ability to bind DNA. Phosphorylated by PAK2 at Thr-2, Thr-8, Thr-89, Thr-93 and Thr-286 thereby promoting JUN-mediated cell proliferation and transformation. Phosphorylated by PLK3 following hypoxia or UV irradiation, leading to increase DNA-binding activity

By similarity.Acetylated at Lys-271 by EP300

By similarity.

Sequence similarities: Belongs to the bZIP family. Jun subfamily.Contains 1 bZIP (basic-leucine zipper) domain.
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 Research Articles on C-JUN    1. The effects of prostaglandin F2alpha administration on transcription factor AP-1 expression and the expression of downstream genes involved in luteolysis are reported.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with C-JUN elisa kitPathways associated with C-JUN elisa kit
 Reference Product  PubMed Publications
 FOS elisa kit  >6367 publications with C-JUN and FOS
 TNF elisa kit  >2605 publications with C-JUN and TNF
 EGF elisa kit  >734 publications with C-JUN and EGF
 HIF1A elisa kit  >247 publications with C-JUN and HIF1A
 IL6 elisa kit  >163 publications with C-JUN and IL6
 IL8 elisa kit  >78 publications with C-JUN and IL8
 IL1B elisa kit  >43 publications with C-JUN and IL1B
 IL12B elisa kit  >18 publications with C-JUN and IL12B
 MAPK9 elisa kit  >9 publications with C-JUN and MAPK9
 MAPK10 elisa kit  >2 publications with C-JUN and MAPK10
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 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
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Diseases associated with C-JUN elisa kitOrgans/Tissues associated with C-JUN elisa kit
 Disease Name  Pubmed Publications
 Death Antibodies  >5410 publications with C-JUN and Death
 Nervous System Diseases Antibodies  >4933 publications with C-JUN and Nervous System Diseases
 Immune System Diseases Antibodies  >3917 publications with C-JUN and Immune System Diseases
 Necrosis Antibodies  >3686 publications with C-JUN and Necrosis
 Central Nervous System Diseases Antibodies  >2920 publications with C-JUN and Central Nervous System Diseases
 Disease Models, Animal Antibodies  >2911 publications with C-JUN and Disease Models, Animal
 Brain Diseases Antibodies  >2822 publications with C-JUN and Brain Diseases
 Congenital Abnormalities Antibodies  >1994 publications with C-JUN and Congenital Abnormalities
 Liver Diseases Antibodies  >1951 publications with C-JUN and Liver Diseases
 Lung Diseases Antibodies  >1781 publications with C-JUN and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6493 publications with C-JUN and Brain
 Embryonic Tissue Antibodies  >1867 publications with C-JUN and Embryonic Tissue
 Intestine Antibodies  >1161 publications with C-JUN and Intestine
 Ovary Antibodies  >761 publications with C-JUN and Ovary
 Adipose Tissue Antibodies  >596 publications with C-JUN and Adipose Tissue
 Thymus Antibodies  >444 publications with C-JUN and Thymus
 Uterus Antibodies  >422 publications with C-JUN and Uterus
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