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CMA1 elisa kit :: Monkey Chymase 1, Mast Cell ELISA Kit

Scan QR to view Datasheet Catalog #    MBS056428 CMA1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Chymase 1, Mast Cell (CMA1), ELISA Kit

★Popular Item★
 Also Known As   

Monkey Chymase 1, Mast Cell ELISA Kit

 Product Gene Name   

CMA1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    118938
 3D Structure    ModBase 3D Structure for P23946
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 Species Reactivity    Monkey
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    62.5 pg/ml - 2000 pg/ml
 Sensitivity    10 pg/ml
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CMA1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CMA1 purchase    MBS056428 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Chymase 1, Mast Cell (CMA1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5 pg/ml - 2000 pg/ml in biological research samples containing CMA1, with an estimated sensitivity of 10 pg/ml. The ELISA analytical biochemical technique of the MBS056428 kit is based on CMA1 antibody-CMA1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CMA1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CMA1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CMA1 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CMA1 (hereafter termed "analyte") in undiluted original Monkey body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS056428. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CMA1. It may not necessarily be applicable to this product.
 NCBI GI #    4502907
 NCBI GeneID    1215
 NCBI Accession #    NP_001827.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001836.3 [Other Products]
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 UniProt Primary Accession #    P23946 [Other Products]
 UniProt Secondary Accession #    Q16018; Q3SY36; Q9UDH5; B5BUM8 [Other Products]
 UniProt Related Accession #    P23946 [Other Products]
 Molecular Weight    27,325 Da
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 NCBI Official Full Name    chymase preproprotein
 NCBI Official Synonym Full Names    chymase 1, mast cell
 NCBI Official Symbol    CMA1 [Similar Products]
 NCBI Official Synonym Symbols   
CYH; MCT1; chymase
[Similar Products]
 NCBI Protein Information    chymase; alpha-chymase; chymase, heart; chymase, mast cell; mast cell protease I; chymase 1 preproprotein transcript E; chymase 1 preproprotein transcript I
 UniProt Protein Name    Chymase
 UniProt Synonym Protein Names   
Alpha-chymase; Mast cell protease I
 Protein Family    Chymase
 UniProt Gene Name    CMA1 [Similar Products]
 UniProt Synonym Gene Names    CYH; CYM [Similar Products]
 UniProt Entry Name    CMA1_HUMAN
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 NCBI Summary for CMA1    This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CMA1    CMA1: Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. Belongs to the peptidase S1 family. Granzyme subfamily.

Protein type: Secreted, signal peptide; Secreted; EC 3.4.21.39; Protease

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: extracellular matrix; extracellular space; extracellular region; intracellular

Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity; peptide binding

Biological Process: interleukin-1 beta biosynthetic process; extracellular matrix disassembly; positive regulation of angiogenesis; extracellular matrix organization and biogenesis; cellular protein metabolic process; midbrain development; regulation of inflammatory response; protein processing; angiotensin maturation; proteolysis
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 Research Articles on CMA1    1. The accumulated data in this review suggest that mast cells, their tryptases, and their chymases play important roles in tissue repair.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CMA1 elisa kitPathways associated with CMA1 elisa kit
 Reference Product  PubMed Publications
 AGT elisa kit  >6 publications with CMA1 and AGT
 REN elisa kit  >2 publications with CMA1 and REN
 ACE2 elisa kit  >1 publications with CMA1 and ACE2
 KITLG elisa kit  >1 publications with CMA1 and KITLG
 Products by Pathway  Pathway Diagram
 ACE Inhibitor Pathway antibodies  ACE Inhibitor Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies  Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with CMA1 elisa kitOrgans/Tissues associated with CMA1 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >10 publications with CMA1 and Inflammation
 Lung Diseases Antibodies  >10 publications with CMA1 and Lung Diseases
 Fibrosis Antibodies  >8 publications with CMA1 and Fibrosis
 Hypertension Antibodies  >8 publications with CMA1 and Hypertension
 Heart Diseases Antibodies  >7 publications with CMA1 and Heart Diseases
 Hypertrophy Antibodies  >5 publications with CMA1 and Hypertrophy
 Neoplasms Antibodies  >5 publications with CMA1 and Neoplasms
 Necrosis Antibodies  >4 publications with CMA1 and Necrosis
 Pulmonary Fibrosis Antibodies  >2 publications with CMA1 and Pulmonary Fibrosis
 Cell Transformation, Neoplastic Antibodies  >2 publications with CMA1 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >1 publications with CMA1 and Mixed
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