NP_066303.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,720 Da
NCBI Official Full Name
complement factor H-related protein 3 isoform 1
NCBI Official Synonym Full Names
complement factor H-related 3
NCBI Official Synonym Symbols
FHR3; HLF4; CFHL3; FHR-3; DOWN16 [Similar Products]
NCBI Protein Information
complement factor H-related protein 3; H factor-like 4; H factor-like protein 3
UniProt Protein Name
Complement factor H-related protein 3
UniProt Synonym Protein Names
DOWN16; H factor-like protein 3
UniProt Synonym Gene Names
UniProt Entry Name
FHR3_HUMAN
NCBI Summary for CFHR3
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Comments for CFHR3
CFHR3: Might be involved in complement regulation. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q32
Cellular Component: extracellular space
Disease: Macular Degeneration, Age-related, 1; Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 1
Research Articles on CFHR3
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Products associated with CFHR3 elisa kit
Pathways associated with CFHR3 elisa kit
Diseases associated with CFHR3 elisa kit
Organs/Tissues associated with CFHR3 elisa kit
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