BAD15375
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,863 Da
NCBI Official Full Name
Ubiquitin activating enzyme
NCBI Official Synonym Full Names
ubiquitin-like modifier activating enzyme 5
NCBI Protein Information
ubiquitin-like modifier-activating enzyme 5; UFM1-activating enzyme; ubiquitin-activating enzyme 5; UBA5, ubiquitin-activating enzyme E1 homolog; ubiquitin-activating enzyme E1-domain containing 1; ubiquitin-activating enzyme E1 domain-containing protein 1
UniProt Protein Name
Ubiquitin-like modifier-activating enzyme 5
UniProt Synonym Protein Names
ThiFP1; UFM1-activating enzyme; Ubiquitin-activating enzyme E1 domain-containing protein 1
UniProt Synonym Gene Names
UniProt Entry Name
UBA5_HUMAN
NCBI Summary for E1/UBAE
This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A pseudogene located on chromosome 1 has also been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for E1/UBAE
UBE1DC1: E1-like enzyme which activates UFM1 and SUMO2. Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system; Autophagy
Chromosomal Location of Human Ortholog: 3q22.1
Cellular Component: intracellular membrane-bound organelle; cytoplasm; cytosol; nucleus
Molecular Function: protein binding; metal ion binding; ATP binding
Biological Process: regulation of estrogen receptor signaling pathway
Research Articles on E1/UBAE
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Products associated with E1/UBAE elisa kit
Pathways associated with E1/UBAE elisa kit
Diseases associated with E1/UBAE elisa kit
Organs/Tissues associated with E1/UBAE elisa kit
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