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EPHA1 elisa kit :: Monkey EPHA1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2510937 EPHA1 elisa kit
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EPHA1, ELISA Kit

 Also Known As   

Monkey EPHA1 (Ephrin Type A Receptor 1) ELISA Kit

 Product Gene Name   

EPHA1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    179610
 3D Structure    ModBase 3D Structure for P21709
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 Species Reactivity    Monkey
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 Specificity    This kit recognizes natural and recombinant Monkey EPHA1. No significant cross-reactivity or interference between Monkey EPHA1 and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.313-20ng/mL
 Sensitivity    Min: 0.188ng/mL; Max: 20ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of EPHA1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for EPHA1 purchase    MBS2510937 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the EPHA1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313-20ng/mL in biological research samples containing EPHA1, with an estimated sensitivity of Min: 0.188ng/mL; Max: 20ng/mL. The ELISA analytical biochemical technique of the MBS2510937 kit is based on EPHA1 antibody-EPHA1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EPHA1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EPHA1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for EPHA1 elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Monkey EPHA1 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to EPHA1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for EPHA1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain EPHA1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of EPHA1. You can calculate the concentration of EPHA1 in the samples by comparing the OD of the samples to the standard curve.
Sample Manual Insert of MBS2510937. Click to request current manual
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NCBI/Uniprot data below describe general gene information for EPHA1. It may not necessarily be applicable to this product.
 NCBI GI #    221316650
 NCBI GeneID    2041
 NCBI Accession #    NP_005223.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_005232.4 [Other Products]
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 UniProt Primary Accession #    P21709 [Other Products]
 UniProt Secondary Accession #    Q15405; A1L3V3; B5A966; B5A967 [Other Products]
 UniProt Related Accession #    P21709 [Other Products]
 Molecular Weight    51,069 Da
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 NCBI Official Full Name    ephrin type-A receptor 1
 NCBI Official Synonym Full Names    EPH receptor A1
 NCBI Official Symbol    EPHA1 [Similar Products]
 NCBI Official Synonym Symbols   
EPH; EPHT; EPHT1
[Similar Products]
 NCBI Protein Information    ephrin type-A receptor 1; eph tyrosine kinase 1; erythropoietin-producing hepatoma amplified sequence; erythropoietin-producing hepatoma receptor; hEpha1; oncogene EPH; soluble EPHA1 variant 1; soluble EPHA1 variant 2; tyrosine-protein kinase receptor EPH
 UniProt Protein Name    Ephrin type-A receptor 1
 UniProt Synonym Protein Names   
EPH tyrosine kinase; EPH tyrosine kinase 1; Erythropoietin-producing hepatoma receptor; Tyrosine-protein kinase receptor EPH
 Protein Family    Ephrin type-A receptor
 UniProt Gene Name    EPHA1 [Similar Products]
 UniProt Synonym Gene Names    EPH; EPHT; EPHT1; hEpha1 [Similar Products]
 UniProt Entry Name    EPHA1_HUMAN
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 NCBI Summary for EPHA1    This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for EPHA1    EphA1: a receptor tyrosine kinase. Receptor for members of the ephrin-A family. Binds with a low affinity to ephrin-A1. The Eph receptor tyrosine kinase family, the largest in the tyrosine kinase group, has fourteen members. They bind membrane-anchored ligands, ephrins, at sites of cell-cell contact, regulating the repulsion and adhesion of cells that underlie the establishment, maintenance, and remodeling of patterns of cellular organization. Eph signals are particularly important in regulating cell adhesion and cell migration during development, axon guidance, homeostasis and disease. EphA receptors bind to GPI-anchored ephrin-A ligands, while EphB receptors bind to ephrin-B proteins that have a transmembrane and cytoplasmic domain. Interactions between EphB receptor kinases and ephrin-B proteins transduce signals bidirectionally, signaling to both interacting cell types. Eph receptors and ephrins also regulate the adhesion of endothelial cells and are required for the remodeling of blood vessels. Misexpressed in several cancers, including upregulation in head and neck cancer, and downregulation in invasive breast cancer cell lines and glioblastoma

Protein type: Protein kinase, TK; Kinase, protein; Membrane protein, integral; EC 2.7.10.1; Protein kinase, tyrosine (receptor); TK group; Eph family

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: transmembrane-ephrin receptor activity; protein kinase binding; ATP binding; protein kinase activity

Biological Process: axon guidance; positive regulation of angiogenesis; cell surface receptor linked signal transduction; peptidyl-tyrosine phosphorylation; somatic stem cell maintenance; protein amino acid autophosphorylation; positive regulation of stress fiber formation; positive regulation of cell proliferation; ephrin receptor signaling pathway; negative regulation of protein kinase activity; angiogenesis; positive regulation of cell-matrix adhesion; negative regulation of cell migration; positive regulation of cell migration
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 Research Articles on EPHA1    1. two states of the EphA1 transmembrane helix dimer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with EPHA1 elisa kitPathways associated with EPHA1 elisa kit
 Reference Product  PubMed Publications
 EPHA2 elisa kit  >36 publications with EPHA1 and EPHA2
 EPHA3 elisa kit  >12 publications with EPHA1 and EPHA3
 SRC elisa kit  >7 publications with EPHA1 and SRC
 EFNA1 elisa kit  >4 publications with EPHA1 and EFNA1
 FYN elisa kit  >1 publications with EPHA1 and FYN
 EFNA5 elisa kit  >1 publications with EPHA1 and EFNA5
 NGEF elisa kit  >1 publications with EPHA1 and NGEF
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies  EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
 EPHA Forward Signaling Pathway antibodies  EPHA Forward Signaling Pathway Diagram
 EPHA-mediated Growth Cone Collapse Pathway antibodies  EPHA-mediated Growth Cone Collapse Pathway Diagram
 POU5F1 (OCT4), SOX2, NANOG Activate Genes Related To Proliferation Pathway antibodies  POU5F1 (OCT4), SOX2, NANOG Activate Genes Related To Proliferation Pathway Diagram
 Transcriptional Regulation Of Pluripotent Stem Cells Pathway antibodies  Transcriptional Regulation Of Pluripotent Stem Cells Pathway Diagram
Diseases associated with EPHA1 elisa kitOrgans/Tissues associated with EPHA1 elisa kit
 Disease Name  Pubmed Publications
 Alzheimer Disease Antibodies  >24 publications with EPHA1 and Alzheimer Disease
 Adenocarcinoma Antibodies  >8 publications with EPHA1 and Adenocarcinoma
 Inflammation Antibodies  >6 publications with EPHA1 and Inflammation
 Colorectal Neoplasms Antibodies  >6 publications with EPHA1 and Colorectal Neoplasms
 Carcinoma, Hepatocellular Antibodies  >4 publications with EPHA1 and Carcinoma, Hepatocellular
 Carcinoma, Squamous Cell Antibodies  >4 publications with EPHA1 and Carcinoma, Squamous Cell
 Cell Transformation, Neoplastic Antibodies  >3 publications with EPHA1 and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >3 publications with EPHA1 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >3 publications with EPHA1 and Breast Neoplasms
 Cognition Disorders Antibodies  >3 publications with EPHA1 and Cognition Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >32 publications with EPHA1 and Brain
 Blood Antibodies  >22 publications with EPHA1 and Blood
 Lung Antibodies  >11 publications with EPHA1 and Lung
 Embryonic Tissue Antibodies  >11 publications with EPHA1 and Embryonic Tissue
 Lymph Node Antibodies  >7 publications with EPHA1 and Lymph Node
 Liver Antibodies  >5 publications with EPHA1 and Liver
 Thymus Antibodies  >3 publications with EPHA1 and Thymus
 Testis Antibodies  >2 publications with EPHA1 and Testis
 Pancreas Antibodies  >2 publications with EPHA1 and Pancreas
 Heart Antibodies  >2 publications with EPHA1 and Heart
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