NP_001186810.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,613 Da
NCBI Official Full Name
early growth response protein 3 isoform 3
NCBI Official Synonym Full Names
early growth response 3
NCBI Official Synonym Symbols
NCBI Protein Information
early growth response protein 3; zinc finger protein pilot
UniProt Protein Name
Early growth response protein 3
UniProt Synonym Protein Names
Zinc finger protein pilot
UniProt Synonym Gene Names
UniProt Entry Name
EGR3_HUMAN
NCBI Summary for EGR3
This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]
UniProt Comments for EGR3
EGR3: Probable transcription factor involved in muscle spindle development. Belongs to the EGR C2H2-type zinc-finger protein family.
Protein type: DNA-binding; C2H2-type zinc finger protein; Transcription factor
Chromosomal Location of Human Ortholog: 8p23-p21
Cellular Component: cytoplasm; nucleus
Molecular Function: DNA binding; metal ion binding; transcription factor activity
Biological Process: circadian rhythm; positive regulation of T cell differentiation in the thymus; muscle development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; cell migration during sprouting angiogenesis; neuromuscular synaptic transmission; positive regulation of endothelial cell proliferation; regulation of gamma-delta T cell differentiation; negative regulation of apoptosis; peripheral nervous system development
Research Articles on EGR3
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Products associated with EGR3 elisa kit
Pathways associated with EGR3 elisa kit
Diseases associated with EGR3 elisa kit
Organs/Tissues associated with EGR3 elisa kit
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