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GDH elisa kit :: Monkey Glutamate Dehydrogenase 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS740758 GDH elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glutamate Dehydrogenase 1 (GDH), ELISA Kit

 Also Known As   

Monkey Glutamate Dehydrogenase 1 ELISA Kit

 Product Gene Name   

GDH elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 Chromosome Location    Chromosome: 10; NC_000010.10 (88809959..88854776, complement). Location: 10q23.3
 OMIM    138130
 3D Structure    ModBase 3D Structure for P00367
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 Species Reactivity    Monkey
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of GDH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GDH purchase    MBS740758 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glutamate Dehydrogenase 1 (GDH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GDH. The ELISA analytical biochemical technique of the MBS740758 kit is based on GDH antibody-GDH antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GDH antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GDH. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for GDH elisa kit    Metabolism
NCBI/Uniprot data below describe general gene information for GDH. It may not necessarily be applicable to this product.
 NCBI GI #    31707
 NCBI GeneID    2746
 NCBI Accession #    CAA30521.1 [Other Products]
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 UniProt Primary Accession #    P00367 [Other Products]
 UniProt Secondary Accession #    Q5TBU3 [Other Products]
 UniProt Related Accession #    P00367; Q14400; Q53GW3; Q59FQ4; Q9UQV0 [Other Products]
 Molecular Weight    61,398 Da
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 NCBI Official Full Name    GDH
 NCBI Official Synonym Full Names    glutamate dehydrogenase 1
 NCBI Official Symbol    GLUD1 [Similar Products]
 NCBI Official Synonym Symbols   
GDH; GDH1; GLUD
[Similar Products]
 NCBI Protein Information    glutamate dehydrogenase 1, mitochondrial; GDH 1; glutamate dehydrogenase (NAD(P)+)
 UniProt Protein Name    Glutamate dehydrogenase 1, mitochondrial
 Protein Family    Glutamate dehydrogenase
 UniProt Gene Name    GLUD1 [Similar Products]
 UniProt Synonym Gene Names    GLUD; GDH 1 [Similar Products]
 UniProt Entry Name    DHE3_HUMAN
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 NCBI Summary for GDH    This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.[provided by RefSeq, Sep 2009]
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 UniProt Comments for GDH    GLUD1: May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. Homohexamer. Subject to allosteric regulation. Activated by ADP. Inhibited by GTP and ATP. ADP can occupy the NADH binding site and activate the enzyme. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Protein type: Other Amino Acids Metabolism - D-Glutamine and D-glutamate; Oxidoreductase; Energy Metabolism - nitrogen; Amino Acid Metabolism - arginine and proline; Mitochondrial; Amino Acid Metabolism - alanine, aspartate and glutamate; EC 1.4.1.3

Chromosomal Location of Human Ortholog: 10q23.3

Cellular Component: mitochondrion; mitochondrial matrix; cytoplasm

Molecular Function: identical protein binding; protein binding; glutamate dehydrogenase activity; glutamate dehydrogenase [NAD(P)+] activity; GTP binding; ADP binding; ATP binding

Biological Process: glutamate catabolic process; substantia nigra development; positive regulation of insulin secretion; glutamine metabolic process; glutamate biosynthetic process; amino acid biosynthetic process

Disease: Hyperinsulinemic Hypoglycemia, Familial, 6
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 Research Articles on GDH    1. Transgenic mice are useful in defining the molecular pathways affected by the over-activation of GLUD transgene in glutamatergic neurons of the brain and spinal cord.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with GDH elisa kitDiseases associated with GDH elisa kit
 Products by Pathway  Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Amino Acid Synthesis And Interconversion (transamination) Pathway antibodies  Amino Acid Synthesis And Interconversion (transamination) Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 D-Glutamine And D-glutamate Metabolism Pathway antibodies  D-Glutamine And D-glutamate Metabolism Pathway Diagram
 D-Glutamine And D-glutamate Metabolism Pathway antibodies  D-Glutamine And D-glutamate Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Proximal Tubule Bicarbonate Reclamation Pathway antibodies  Proximal Tubule Bicarbonate Reclamation Pathway Diagram
 Disease Name  Pubmed Publications
 Hyperinsulinism Antibodies  >38 publications with GDH and Hyperinsulinism
 Hyperammonemia Antibodies  >19 publications with GDH and Hyperammonemia
 Brain Diseases Antibodies  >10 publications with GDH and Brain Diseases
 Nervous System Diseases Antibodies  >9 publications with GDH and Nervous System Diseases
 Seizures Antibodies  >7 publications with GDH and Seizures
 Hyperplasia Antibodies  >4 publications with GDH and Hyperplasia
 Hyperinsulinemic hypoglycemia, familial, 6 Antibodies  >3 publications with GDH and Hyperinsulinemic hypoglycemia, familial, 6
 Movement Disorders Antibodies  >2 publications with GDH and Movement Disorders
 Inflammation Antibodies  >2 publications with GDH and Inflammation
 Neurodegenerative Diseases Antibodies  >2 publications with GDH and Neurodegenerative Diseases
Organs/Tissues associated with GDH elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >28 publications with GDH and Brain
 Pancreas Antibodies  >17 publications with GDH and Pancreas
 Blood Antibodies  >13 publications with GDH and Blood
 Nerve Antibodies  >11 publications with GDH and Nerve
 Testis Antibodies  >6 publications with GDH and Testis
 Liver Antibodies  >5 publications with GDH and Liver
 Placenta Antibodies  >2 publications with GDH and Placenta
 Kidney Antibodies  >2 publications with GDH and Kidney
 Thyroid Antibodies  >1 publications with GDH and Thyroid
 Eye Antibodies  >1 publications with GDH and Eye
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