NP_055179.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,501 Da
NCBI Official Full Name
glyceraldehyde-3-phosphate dehydrogenase, testis-specific
NCBI Official Synonym Full Names
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
NCBI Official Synonym Symbols
GAPD2; GAPDS; HSD-35; GAPDH-2; HEL-S-278 [Similar Products]
NCBI Protein Information
glyceraldehyde-3-phosphate dehydrogenase, testis-specific
UniProt Protein Name
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
UniProt Synonym Protein Names
Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; GAPDH-2; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase
UniProt Synonym Gene Names
UniProt Entry Name
G3PT_HUMAN
NCBI Summary for GAPDHS
This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008]
UniProt Comments for GAPDHS
GAPDH-2: May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility. Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Protein type: EC 1.2.1.12; Oxidoreductase
Chromosomal Location of Human Ortholog: 19q13.12
Cellular Component: cytosol; nucleus
Molecular Function: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity; protein binding
Biological Process: gluconeogenesis; positive regulation of glycolysis; sperm motility
Research Articles on GAPDHS
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Organs/Tissues associated with GAPDHS elisa kit
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