P11150.3
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55,914 Da
NCBI Official Full Name
Hepatic triacylglycerol lipase
NCBI Official Synonym Full Names
lipase, hepatic
NCBI Protein Information
hepatic triacylglycerol lipase; hepatic lipase; lipase member C
UniProt Protein Name
Hepatic triacylglycerol lipase
UniProt Synonym Protein Names
Lipase member C
UniProt Synonym Gene Names
UniProt Entry Name
LIPC_HUMAN
NCBI Summary for HDL-C
LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008]
UniProt Comments for HDL-C
LIPC: Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin. Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency). A disorder characterized by elevated levels of beta-migrating very low density lipoproteins, and abnormally triglyceride-rich low and high density lipoproteins. Belongs to the AB hydrolase superfamily. Lipase family.
Protein type: Secreted, signal peptide; Secreted; EC 3.1.1.3; Phospholipase; Lipid Metabolism - glycerolipid
Chromosomal Location of Human Ortholog: 15q21-q23
Cellular Component: extracellular space
Molecular Function: heparin binding; triacylglycerol lipase activity; low-density lipoprotein binding; apolipoprotein binding; phospholipase activity
Biological Process: cholesterol metabolic process; cholesterol homeostasis; reverse cholesterol transport; triacylglycerol catabolic process; fatty acid biosynthetic process
Disease: High Density Lipoprotein Cholesterol Level Quantitative Trait Locus 12; Hepatic Lipase Deficiency; Diabetes Mellitus, Noninsulin-dependent
Research Articles on HDL-C
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with HDL-C elisa kit
Pathways associated with HDL-C elisa kit
Diseases associated with HDL-C elisa kit
Organs/Tissues associated with HDL-C elisa kit
|