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INB elisa kit :: Monkey Inhibin B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS739085
Typical Standard Curve/Testing Data
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Inhibin B (INB), ELISA Kit

★Popular Item★
 Also Known As   

Monkey Inhibin B ELISA Kit

 Product Gene Name   

INB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    147390
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 Species Reactivity    Monkey
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 Specificity    This assay has high sensitivity and excellent specificity for detection of INHB. No significant cross-reactivity or interference between INHB and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between INHB and all the analogues, therefore, cross reaction may still exist in some cases.
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Sandwich
 Detection Range    50-1000pg/mL
 Sensitivity    1.0pg/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of INB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for INB purchase    MBS739085 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Inhibin B (INB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 50-1000pg/mL in biological research samples containing INB, with an estimated sensitivity of 1.0pg/mL. The ELISA analytical biochemical technique of the MBS739085 kit is based on INB antibody-INB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect INB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, INB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for INB elisa kit

   Intended Uses: This INHB ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Monkey INHB. This ELISA kit for research use only, not for therapeutic or diagnostic applications!

Principle of the Assay: INHB ELISA kit applies the competitive enzyme immunoassay technique utilizing a polyclonal anti-INHB antibody and an INHB-HRP conjugate. The assay sample and buffer are incubated together with INHB-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the INHB concentration since INHB from samples and INHB-HRP conjugate compete for the anti-INHB antibody binding site. Since the number of sites is limited, as more sites are occupied by INHB from the sample, fewer sites are left to bind INHB-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The INHB concentration in each sample is interpolated from this standard curve.
 Product Categories/Family for INB elisa kit    Neurobiology
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 Typical Standard Curve/Testing Data of INB elisa kit    INB elisa kit Typical Standard Curve/Testing Data image
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Sample Manual Insert of MBS739085. Click to request current manual
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NCBI/Uniprot data below describe general gene information for INB. It may not necessarily be applicable to this product.
 NCBI GI #    154813204
 NCBI GeneID    3625
 NCBI Accession #    NP_002184.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002193.2 [Other Products]
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 UniProt Secondary Accession #    Q53T31; Q8N1D3 [Other Products]
 UniProt Related Accession #    P09529 [Other Products]
 Molecular Weight    45,122 Da
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 NCBI Official Full Name    inhibin beta B chain preproprotein
 NCBI Official Synonym Full Names    inhibin, beta B
 NCBI Official Symbol    INHBB [Similar Products]
 NCBI Protein Information    inhibin beta B chain; Inhibin, beta-2; activin beta-B chain; activin AB beta polypeptide
 UniProt Protein Name    Inhibin beta B chain
 UniProt Synonym Protein Names   
Activin beta-B chain
 Protein Family    Inhibin
 UniProt Gene Name    INHBB [Similar Products]
 UniProt Entry Name    INHBB_HUMAN
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 NCBI Summary for INB    The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq, Jul 2008]
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 UniProt Comments for INB    INHBB: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Belongs to the TGF-beta family.

Protein type: Cytokine; Cell development/differentiation; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2cen-q13

Cellular Component: extracellular space; perinuclear region of cytoplasm; extracellular region

Molecular Function: protein binding; protein homodimerization activity; growth factor activity; hormone activity; cytokine activity; host cell surface receptor binding; transforming growth factor beta receptor binding

Biological Process: fat cell differentiation; activin receptor signaling pathway; defense response; negative regulation of hepatocyte growth factor biosynthetic process; cellular response to starvation; negative regulation of follicle-stimulating hormone secretion; negative regulation of insulin secretion; regulation of apoptosis; ovarian follicle development; cellular response to insulin stimulus; response to mechanical stimulus; regulation of MAPKKK cascade; positive regulation of follicle-stimulating hormone secretion; cell differentiation; cell development; oocyte development; growth
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 Research Articles on INB    1. inhibin B levels, but not FSH, are increased in primary hypothyroidism, which is consistent with a hypogonadotrophic hypogonadal state affecting the reproductive segment of the gonadotrophic axis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with INB elisa kitPathways associated with INB elisa kit
 Reference Product  PubMed Publications
 INHBA elisa kit  >22 publications with INB and INHBA
 INHA elisa kit  >16 publications with INB and INHA
 FST elisa kit  >8 publications with INB and FST
 FSHB elisa kit  >2 publications with INB and FSHB
 INHBC elisa kit  >2 publications with INB and INHBC
 ACVR1B elisa kit  >2 publications with INB and ACVR1B
 INHBE elisa kit  >1 publications with INB and INHBE
 ACVR2A elisa kit  >1 publications with INB and ACVR2A
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Antagonism Of Activin By Follistatin Pathway antibodies  Antagonism Of Activin By Follistatin Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Glycoprotein Hormones Pathway antibodies  Glycoprotein Hormones Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Biosynthesis Pathway antibodies  Peptide Hormone Biosynthesis Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Activin Pathway antibodies  Signaling By Activin Pathway Diagram
Diseases associated with INB elisa kitOrgans/Tissues associated with INB elisa kit
 Disease Name  Pubmed Publications
 Ovarian Diseases Antibodies  >8 publications with INB and Ovarian Diseases
 Infertility, Male Antibodies  >7 publications with INB and Infertility, Male
 Adenocarcinoma Antibodies  >7 publications with INB and Adenocarcinoma
 Ovarian Neoplasms Antibodies  >6 publications with INB and Ovarian Neoplasms
 Prostatic Neoplasms Antibodies  >4 publications with INB and Prostatic Neoplasms
 Weight Loss Antibodies  >3 publications with INB and Weight Loss
 Disease Models, Animal Antibodies  >3 publications with INB and Disease Models, Animal
 Breast Neoplasms Antibodies  >3 publications with INB and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >3 publications with INB and Neoplasm Metastasis
 Congenital Abnormalities Antibodies  >3 publications with INB and Congenital Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >21 publications with INB and Testis
 Brain Antibodies  >10 publications with INB and Brain
 Uterus Antibodies  >7 publications with INB and Uterus
 Liver Antibodies  >6 publications with INB and Liver
 Pancreas Antibodies  >5 publications with INB and Pancreas
 Prostate Antibodies  >4 publications with INB and Prostate
 Kidney Antibodies  >4 publications with INB and Kidney
 Eye Antibodies  >3 publications with INB and Eye
 Nerve Antibodies  >2 publications with INB and Nerve
 Lung Antibodies  >2 publications with INB and Lung
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