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IKB elisa kit :: Monkey Inhibitor K Binding ELISA Kit

Scan QR to view Datasheet Catalog #    MBS009003 IKB elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Inhibitor K Binding (IKB), ELISA Kit

 Also Known As   

Monkey Inhibitor K Binding ELISA Kit

 Product Gene Name   

IKB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    603258
 3D Structure    ModBase 3D Structure for O14920
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 Species Reactivity    Monkey
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IKB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IKB purchase    MBS009003 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Inhibitor K Binding (IKB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IKB. The ELISA analytical biochemical technique of the MBS009003 kit is based on IKB antibody-IKB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IKB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IKB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for IKB. It may not necessarily be applicable to this product.
 NCBI GI #    4185275
 NCBI GeneID    3551
 NCBI Accession #    AAD08997.1 [Other Products]
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 UniProt Primary Accession #    O14920 [Other Products]
 UniProt Secondary Accession #    O75327; B4DZ30; B4E0U4 [Other Products]
 UniProt Related Accession #    O14920 [Other Products]
 Molecular Weight    86,564 Da
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 NCBI Official Full Name    IkB kinase-b
 NCBI Official Synonym Full Names    inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
 NCBI Official Symbol    IKBKB [Similar Products]
 NCBI Official Synonym Symbols   
IKK2; IKKB; IMD15; NFKBIKB; IKK-beta
[Similar Products]
 NCBI Protein Information    inhibitor of nuclear factor kappa-B kinase subunit beta; IKK-B; I-kappa-B kinase 2; I-kappa-B-kinase beta; nuclear factor NF-kappa-B inhibitor kinase beta
 UniProt Protein Name    Inhibitor of nuclear factor kappa-B kinase subunit beta
 UniProt Synonym Protein Names   
I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta
 UniProt Gene Name    IKBKB [Similar Products]
 UniProt Synonym Gene Names    IKKB; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; IKK2; NFKBIKB [Similar Products]
 UniProt Entry Name    IKKB_HUMAN
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 NCBI Summary for IKB    The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011]
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 UniProt Comments for IKB    IKKB: a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.

Protein type: Protein kinase, Other; EC 2.7.11.10; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Other group; IKK family

Chromosomal Location of Human Ortholog: 8p11.2

Cellular Component: internal side of plasma membrane; cytoplasm; IkappaB kinase complex; nucleus; cytosol; lipid raft

Molecular Function: protein serine/threonine kinase activity; protein binding; protein homodimerization activity; IkappaB kinase activity; protein heterodimerization activity; protein kinase binding; ATP binding; protein kinase activity

Biological Process: I-kappaB kinase/NF-kappaB cascade; nerve growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; toll-like receptor 3 signaling pathway; protein amino acid phosphorylation; T cell receptor signaling pathway; toll-like receptor 10 signaling pathway; activation of NF-kappaB transcription factor; toll-like receptor 5 signaling pathway; B cell homeostasis; positive regulation of interferon type I production; inflammatory response; toll-like receptor 4 signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; MyD88-independent toll-like receptor signaling pathway; response to virus; toll-like receptor 2 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; serine phosphorylation of STAT protein; toll-like receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor 9 signaling pathway; I-kappaB phosphorylation; negative regulation of apoptosis

Disease: Immunodeficiency 15
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 Research Articles on IKB    1. IkBalpha kinase (IKK)-signaling is necessary to allow ZNF395 to activate transcription and simultaneously enhances its proteolytic degradation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IKB elisa kitPathways associated with IKB elisa kit
 Reference Product  PubMed Publications
 CHUK elisa kit  >1174 publications with IKB and CHUK
 RELA elisa kit  >508 publications with IKB and RELA
 IKBKG elisa kit  >286 publications with IKB and IKBKG
 NFKB1 elisa kit  >45 publications with IKB and NFKB1
 NFKBIA elisa kit  >13 publications with IKB and NFKBIA
 TNFRSF1A elisa kit  >12 publications with IKB and TNFRSF1A
 UBC elisa kit  >6 publications with IKB and UBC
 MAP3K14 elisa kit  >5 publications with IKB and MAP3K14
 MAP3K7 elisa kit  >4 publications with IKB and MAP3K7
 NFKBIB elisa kit  >2 publications with IKB and NFKBIB
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Activation Of NF-kappaB In B Cells Pathway antibodies  Activation Of NF-kappaB In B Cells Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
Diseases associated with IKB elisa kitOrgans/Tissues associated with IKB elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1264 publications with IKB and Necrosis
 Inflammation Antibodies  >1014 publications with IKB and Inflammation
 Neoplasms Antibodies  >795 publications with IKB and Neoplasms
 Breast Neoplasms Antibodies  >119 publications with IKB and Breast Neoplasms
 Liver Diseases Antibodies  >114 publications with IKB and Liver Diseases
 Cell Transformation, Neoplastic Antibodies  >102 publications with IKB and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >80 publications with IKB and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >63 publications with IKB and Lung Neoplasms
 Atherosclerosis Antibodies  >58 publications with IKB and Atherosclerosis
 Fibrosis Antibodies  >58 publications with IKB and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >717 publications with IKB and Blood
 Vascular Antibodies  >273 publications with IKB and Vascular
 Lung Antibodies  >257 publications with IKB and Lung
 Muscle Antibodies  >227 publications with IKB and Muscle
 Liver Antibodies  >218 publications with IKB and Liver
 Skin Antibodies  >177 publications with IKB and Skin
 Brain Antibodies  >148 publications with IKB and Brain
 Bone Antibodies  >147 publications with IKB and Bone
 Heart Antibodies  >122 publications with IKB and Heart
 Kidney Antibodies  >109 publications with IKB and Kidney
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