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ITGbeta1 elisa kit :: Monkey Integrin beta1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS010928 ITGbeta1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Integrin beta1 (ITGbeta1), ELISA Kit

 Also Known As   

Monkey Integrin beta1 ELISA Kit

 Product Gene Name   

ITGbeta1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 10; NC_000010.10 (33189246..33247293, complement). Location: 10p11.2
 OMIM    135630
 3D Structure    ModBase 3D Structure for P05556
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 Species Reactivity    Monkey
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ITGbeta1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ITGbeta1 purchase    MBS010928 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Integrin beta1 (ITGbeta1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ITGbeta1. The ELISA analytical biochemical technique of the MBS010928 kit is based on ITGbeta1 antibody-ITGbeta1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ITGbeta1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ITGbeta1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ITGbeta1. It may not necessarily be applicable to this product.
 NCBI GI #    19743823
 NCBI GeneID    3688
 NCBI Accession #    NP_596867.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_133376.2 [Other Products]
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 UniProt Primary Accession #    P05556 [Other Products]
 UniProt Secondary Accession #    P78466; P78467; Q13089; Q13090; Q13091; Q13212; A8K6N2; D3DRX9; D3DRY3; D3DRY4; D3DRY5 [Other Products]
 UniProt Related Accession #    P05556 [Other Products]
 Molecular Weight    88,415 Da
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 NCBI Official Full Name    integrin beta-1 isoform 1A
 NCBI Official Synonym Full Names    integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 NCBI Official Symbol    ITGB1 [Similar Products]
 NCBI Official Synonym Symbols   
CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA
[Similar Products]
 NCBI Protein Information    integrin beta-1; glycoprotein IIa; integrin VLA-4 beta subunit; very late activation protein, beta polypeptide
 UniProt Protein Name    Integrin beta-1
 UniProt Synonym Protein Names   
Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; VLA-4 subunit beta
 UniProt Gene Name    ITGB1 [Similar Products]
 UniProt Synonym Gene Names    FNRB; MDF2; MSK12; GPIIA [Similar Products]
 UniProt Entry Name    ITB1_HUMAN
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 NCBI Summary for ITGbeta1    Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ITGbeta1    ITGB1: an integral membrane protein that heterodimerizes with an alpha-3 chain, forming a receptor for many extracellular-matrix proteins including fibronectin, laminin, collagen, epiligrin and thrombospondin. . Beta 1 integrins recognize the amino-acid motif RGD in a wide array of ligands. Five alternatively spliced variants with alternate carboxy termini have been described. Two alternatively spliced isoforms have been described. Isoform beta-1a is widely expressed; other isoforms are generally expressed with a more restricted distribution. Isoform beta-1b is expressed in skin, liver, skeletal muscle, cardiac muscle, placenta, umbilical vein endothelial cells, neuroblastoma cells, lymphoma cells, hepatoma cells and astrocytoma cells. Isoforms beta-1c and beta-1c-2 are expressed in muscle, kidney, liver, placenta, cervical epithelium, umbilical vein endothelial cells, fibroblast cells, embryonal kidney cells, platelets and several blood cell lines. Isoform beta-c-2, rather than isoform beta-1c, is selectively expressed in primary t-cells. Isoform beta-1c is expressed in nonproliferating and differentiated prostate gland epithelial cells. Isoform beta-1d is expressed specifically in striated muscle (skeletal and cardiac muscle).

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion; Cell surface; Receptor, misc.

Chromosomal Location of Human Ortholog: 10p11.2

Cellular Component: cell surface; focal adhesion; acrosome; dendritic spine; lipid raft; ruffle; recycling endosome; membrane; hemidesmosome; lamellipodium; cytoplasm; plasma membrane; melanosome; basement membrane; integrin complex; neuromuscular junction; receptor complex; sarcolemma; filopodium; external side of plasma membrane; cleavage furrow

Molecular Function: protein domain specific binding; protease binding; metal ion binding; laminin binding; actin binding; alpha-actinin binding; peptide binding; protein kinase binding; integrin binding; viral receptor activity; protein binding; protein heterodimerization activity; fibronectin binding; cell adhesion molecule binding; glycoprotein binding

Biological Process: extracellular matrix organization and biogenesis; maternal process involved in pregnancy; positive regulation of apoptosis; axon extension; regulation of cell cycle; mesodermal cell differentiation; positive regulation of endocytosis; cardiac muscle cell differentiation; leukocyte adhesion; transforming growth factor beta receptor signaling pathway; germ cell migration; tissue homeostasis; response to drug; dendrite morphogenesis; protein transport within lipid bilayer; negative regulation of neuron differentiation; positive regulation of peptidyl-tyrosine phosphorylation; cell migration during sprouting angiogenesis; B cell differentiation; cell-cell adhesion mediated by integrin; response to activity; leukocyte migration; regulation of G-protein coupled receptor protein signaling pathway; G1/S transition of mitotic cell cycle; axon guidance; entry of virus into host cell; cell-matrix adhesion; cell fate specification; negative regulation of cell proliferation; positive regulation of MAPKKK cascade; positive regulation of cell proliferation; visual learning; negative regulation of cell projection organization and biogenesis; integrin-mediated signaling pathway; regulation of immune response; cell migration; in utero embryonic development; sarcomere organization; cell-substrate adhesion; formation of radial glial scaffolds; cellular calcium ion homeostasis; heterotypic cell-cell adhesion; negative regulation of Rho protein signal transduction; calcium-independent cell-matrix adhesion; stress fiber formation; cellular defense response; blood coagulation; homophilic cell adhesion; leukocyte tethering or rolling; positive regulation of cell migration
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 Research Articles on ITGbeta1    1. provide the first evidence that beta(1) integrin-dependent migratory and metastatic competence of prostate cancer cells is enhanced by Trop-2
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ITGbeta1 elisa kitDiseases associated with ITGbeta1 elisa kit
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies  Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >25 publications with ITGbeta1 and Neoplasms
 Carcinoma Antibodies  >11 publications with ITGbeta1 and Carcinoma
 Inflammation Antibodies  >6 publications with ITGbeta1 and Inflammation
 Nervous System Diseases Antibodies  >6 publications with ITGbeta1 and Nervous System Diseases
 Neoplasm Invasiveness Antibodies  >6 publications with ITGbeta1 and Neoplasm Invasiveness
 Fibrosis Antibodies  >4 publications with ITGbeta1 and Fibrosis
 Cardiovascular Diseases Antibodies  >4 publications with ITGbeta1 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >3 publications with ITGbeta1 and Kidney Diseases
 Necrosis Antibodies  >3 publications with ITGbeta1 and Necrosis
 Lung Diseases Antibodies  >3 publications with ITGbeta1 and Lung Diseases
Organs/Tissues associated with ITGbeta1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >15 publications with ITGbeta1 and Blood
 Brain Antibodies  >13 publications with ITGbeta1 and Brain
 Vascular Antibodies  >11 publications with ITGbeta1 and Vascular
 Bone Antibodies  >10 publications with ITGbeta1 and Bone
 Muscle Antibodies  >8 publications with ITGbeta1 and Muscle
 Embryonic Tissue Antibodies  >8 publications with ITGbeta1 and Embryonic Tissue
 Lung Antibodies  >7 publications with ITGbeta1 and Lung
 Uterus Antibodies  >6 publications with ITGbeta1 and Uterus
 Liver Antibodies  >6 publications with ITGbeta1 and Liver
 Kidney Antibodies  >6 publications with ITGbeta1 and Kidney
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