NP_001248377.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,905 Da
NCBI Official Full Name
neuronal membrane glycoprotein M6-a isoform 4
NCBI Official Synonym Full Names
glycoprotein M6A
NCBI Official Synonym Symbols
NCBI Protein Information
neuronal membrane glycoprotein M6-a
UniProt Protein Name
Neuronal membrane glycoprotein M6-a
UniProt Synonym Gene Names
UniProt Entry Name
GPM6A_HUMAN
UniProt Comments for GPM6A
GPM6A: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. Belongs to the myelin proteolipid protein family.
Protein type: Membrane protein, multi-pass; Channel, calcium; Membrane protein, integral; Cell surface
Chromosomal Location of Human Ortholog: 4q34
Cellular Component: cell soma; dendritic spine; filopodium; integral to membrane; neuron projection; plasma membrane
Molecular Function: calcium channel activity; protein binding
Biological Process: neurite morphogenesis; neuron migration; positive regulation of filopodium formation; stem cell differentiation; synaptogenesis
Research Articles on GPM6A
Precautions
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Diseases associated with GPM6A elisa kit
Organs/Tissues associated with GPM6A elisa kit
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