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NTRK2 elisa kit :: Monkey Neurotrophic Tyrosine Kinase Receptor Type 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS017254 NTRK2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2), ELISA Kit

 Also Known As   

Monkey Neurotrophic Tyrosine Kinase Receptor Type 2 ELISA Kit

 Product Gene Name   

NTRK2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 9; NC_000009.11 (87283466..87638505). Location: 9q22.1
 OMIM    600456
 3D Structure    ModBase 3D Structure for Q16620
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 Species Reactivity    Monkey
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NTRK2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NTRK2 purchase    MBS017254 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NTRK2. The ELISA analytical biochemical technique of the MBS017254 kit is based on NTRK2 antibody-NTRK2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NTRK2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NTRK2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for NTRK2. It may not necessarily be applicable to this product.
 NCBI GI #    15217077
 NCBI GeneID    4915
 NCBI Accession #    AAK92490.1 [Other Products]
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 UniProt Primary Accession #    Q16620 [Other Products]
 UniProt Secondary Accession #    Q16675; Q59GJ1; Q8WXJ5; Q8WXJ6; Q8WXJ7; B1ANZ4; B4DFV9 [Other Products]
 UniProt Related Accession #    Q16620 [Other Products]
 Molecular Weight    91,999 Da
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 NCBI Official Full Name    neurotrophic tyrosine kinase receptor type 2
 NCBI Official Synonym Full Names    neurotrophic tyrosine kinase, receptor, type 2
 NCBI Official Symbol    NTRK2 [Similar Products]
 NCBI Official Synonym Symbols   
TRKB; trk-B; GP145-TrkB
[Similar Products]
 NCBI Protein Information    BDNF/NT-3 growth factors receptor; trkB tyrosine kinase; tyrosine kinase receptor B; tropomyosin-related kinase B; BDNF-tropomyosine receptor kinase B
 UniProt Protein Name    BDNF/NT-3 growth factors receptor
 UniProt Synonym Protein Names   
GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B
 Protein Family    BDNF/NT-3 growth factors receptor
 UniProt Gene Name    NTRK2 [Similar Products]
 UniProt Synonym Gene Names    TRKB; Trk-B [Similar Products]
 UniProt Entry Name    NTRK2_HUMAN
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 NCBI Summary for NTRK2    This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NTRK2    TrkB: a receptor tyrosine kinase of the Trk family. Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3, -4 and -5 but not nerve growth factor (NGF). Involved in the development and maintenance of the nervous system. Three splice variant isoforms have been described.

Protein type: Protein kinase, TK; Membrane protein, integral; EC 2.7.10.1; Kinase, protein; Protein kinase, tyrosine (receptor); TK group; Trk family

Chromosomal Location of Human Ortholog: 9q22.1

Cellular Component: cell surface; rough endoplasmic reticulum; integral to plasma membrane; dendritic spine; terminal button; excitatory synapse; perikaryon; cytosol; postsynaptic membrane; growth cone; presynaptic active zone; endosome membrane; receptor complex

Molecular Function: brain-derived neurotrophic factor receptor activity; neurotrophin binding; protein homodimerization activity; ephrin receptor binding; brain-derived neurotrophic factor binding; ATP binding

Biological Process: circadian rhythm; mechanoreceptor differentiation; retinal rod cell development; peptidyl-tyrosine phosphorylation; nerve growth factor receptor signaling pathway; protein amino acid autophosphorylation; regulation of dendrite development; neuron migration; regulation of neurotransmitter secretion; positive regulation of synaptic transmission, glutamatergic; neuron differentiation; positive regulation of MAPKKK cascade; positive regulation of cell proliferation; oligodendrocyte differentiation; feeding behavior; negative regulation of neuron apoptosis; vasculogenesis; inflammatory response; neuromuscular junction development; central nervous system neuron development; aging; response to light stimulus; brain-derived neurotrophic factor receptor signaling pathway; adenylate cyclase activation; regulation of protein kinase B signaling cascade; learning; positive regulation of peptidyl-serine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; peripheral nervous system neuron development; glutamate secretion; long-term memory; positive regulation of axonogenesis; cerebral cortex development; transmembrane receptor protein tyrosine kinase signaling pathway

Disease: Obesity, Hyperphagia, And Developmental Delay
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 Research Articles on NTRK2    1. These results suggest that TrkB and TrkC have a tumor progressive function and may be a useful diagnostic and therapeutic target in colorectal cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NTRK2 elisa kitPathways associated with NTRK2 elisa kit
 Reference Product  PubMed Publications
 BDNF elisa kit  >2310 publications with NTRK2 and BDNF
 NGFR elisa kit  >31 publications with NTRK2 and NGFR
 SHC1 elisa kit  >15 publications with NTRK2 and SHC1
 NTF4 elisa kit  >6 publications with NTRK2 and NTF4
 SHC3 elisa kit  >4 publications with NTRK2 and SHC3
 NTF3 elisa kit  >4 publications with NTRK2 and NTF3
 SHC2 elisa kit  >3 publications with NTRK2 and SHC2
 SH2B1 elisa kit  >2 publications with NTRK2 and SH2B1
 GIPC1 elisa kit  >1 publications with NTRK2 and GIPC1
 PLCG1 elisa kit  >1 publications with NTRK2 and PLCG1
 Products by Pathway  Pathway Diagram
 Activation Of TRKA Receptors Pathway antibodies  Activation Of TRKA Receptors Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 NGF Signalling Via TRKA From The Plasma Membrane Pathway antibodies  NGF Signalling Via TRKA From The Plasma Membrane Pathway Diagram
 NGF-independant TRKA Activation Pathway antibodies  NGF-independant TRKA Activation Pathway Diagram
 Neurotrophic Factor-mediated Trk Receptor Signaling Pathway antibodies  Neurotrophic Factor-mediated Trk Receptor Signaling Pathway Diagram
 Neurotrophin Signaling Pathway antibodies  Neurotrophin Signaling Pathway Diagram
Diseases associated with NTRK2 elisa kitOrgans/Tissues associated with NTRK2 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >495 publications with NTRK2 and Nervous System Diseases
 Brain Diseases Antibodies  >388 publications with NTRK2 and Brain Diseases
 Neoplasms Antibodies  >278 publications with NTRK2 and Neoplasms
 Mental Disorders Antibodies  >226 publications with NTRK2 and Mental Disorders
 Disease Models, Animal Antibodies  >187 publications with NTRK2 and Disease Models, Animal
 Neuroblastoma Antibodies  >126 publications with NTRK2 and Neuroblastoma
 Nerve Degeneration Antibodies  >91 publications with NTRK2 and Nerve Degeneration
 Cardiovascular Diseases Antibodies  >89 publications with NTRK2 and Cardiovascular Diseases
 Pain Antibodies  >84 publications with NTRK2 and Pain
 Drug Toxicity Antibodies  >82 publications with NTRK2 and Drug Toxicity
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2485 publications with NTRK2 and Brain
 Kidney Antibodies  >32 publications with NTRK2 and Kidney
 Spleen Antibodies  >7 publications with NTRK2 and Spleen
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