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DFFB elisa kit :: Monkey caspase activated deoxyribonuclease, CAD ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7237885 DFFB elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

caspase activated deoxyribonuclease, CAD (DFFB), ELISA Kit

 Also Known As   

Monkey caspase activated deoxyribonuclease, CAD ELISA Kit

 Product Gene Name   

DFFB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Species Reactivity    Monkey
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DFFB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DFFB purchase    MBS7237885 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the caspase activated deoxyribonuclease, CAD (DFFB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DFFB. The ELISA analytical biochemical technique of the MBS7237885 kit is based on DFFB antibody-DFFB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DFFB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DFFB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for DFFB elisa kit    Cell Biology
NCBI/Uniprot data below describe general gene information for DFFB. It may not necessarily be applicable to this product.
 NCBI GI #    13249028
 NCBI GeneID    84359
 NCBI Accession #    AAK16646.1 [Other Products]
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 UniProt Related Accession #    Q99N34 [Other Products]
 Molecular Weight    40,097 Da
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 NCBI Official Full Name    caspase-activated deoxyribonuclease
 NCBI Official Synonym Full Names    DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
 NCBI Official Symbol    Dffb [Similar Products]
 NCBI Official Synonym Symbols   
Cad
[Similar Products]
 NCBI Protein Information    DNA fragmentation factor subunit beta; DFF-40; caspase-activated DNase; caspase-activated deoxyribonuclease; DNA fragmentation factor, beta subunit; DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor, beta polypeptide (caspase-activated DNase); DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase); DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase)
 UniProt Protein Name    DNA fragmentation factor subunit beta
 UniProt Synonym Protein Names   
Caspase-activated deoxyribonuclease; CAD; Caspase-activated DNase; DNA fragmentation factor 40 kDa subunit; DFF-40
 Protein Family    DNA fragmentation factor
 UniProt Gene Name    Dffb [Similar Products]
 UniProt Synonym Gene Names    Cad; CAD; Caspase-activated DNase; DFF-40 [Similar Products]
 UniProt Entry Name    DFFB_RAT
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 NCBI Summary for DFFB    endogenous endonuclease; mediates caspase-3-dependent internucleosomal DNA degradation and related nuclear alterations [RGD, Feb 2006]
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 UniProt Comments for DFFB    DFFB: Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Deoxyribonuclease; Hydrolase; Apoptosis; Transferase; EC 3.-.-.-

Cellular Component: cytoplasm; nuclear chromatin; nucleolus; cytosol; nucleus

Molecular Function: protein binding; enzyme binding; nuclease activity; DNA binding; deoxyribonuclease activity

Biological Process: brain development; DNA fragmentation during apoptosis; apoptotic chromosome condensation
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 Research Articles on DFFB    1. DNA fragmentation in neuronal apoptosis is catalyzed by either CAD or DNase gamma depending on the differentiation state
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DFFB elisa kitPathways associated with DFFB elisa kit
 Reference Product  PubMed Publications
 Casp3 elisa kit  >38 publications with DFFB and Casp3
 Dffa elisa kit  >5 publications with DFFB and Dffa
 Casp7 elisa kit  >4 publications with DFFB and Casp7
 Products by Pathway  Pathway Diagram
 Activation Of DNA Fragmentation Factor Pathway antibodies  Activation Of DNA Fragmentation Factor Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Induced DNA Fragmentation Pathway antibodies  Apoptosis Induced DNA Fragmentation Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 FAS Pathway And Stress Induction Of HSP Regulation antibodies  FAS Pathway And Stress Induction Of HSP Regulation Diagram
 Relationship Between Glutathione And NADPH Pathway antibodies  Relationship Between Glutathione And NADPH Pathway Diagram
Diseases associated with DFFB elisa kitOrgans/Tissues associated with DFFB elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >12 publications with DFFB and Necrosis
 Carcinoma Antibodies  >7 publications with DFFB and Carcinoma
 Neoplasms, Experimental Antibodies  >4 publications with DFFB and Neoplasms, Experimental
 Immune System Diseases Antibodies  >4 publications with DFFB and Immune System Diseases
 Adenocarcinoma Antibodies  >4 publications with DFFB and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >3 publications with DFFB and Cardiovascular Diseases
 Cognition Disorders Antibodies  >3 publications with DFFB and Cognition Disorders
 Inflammation Antibodies  >2 publications with DFFB and Inflammation
 Liver Diseases Antibodies  >2 publications with DFFB and Liver Diseases
 Disease Models, Animal Antibodies  >2 publications with DFFB and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with DFFB and Brain
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