AAC52118.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
70,108 Da
NCBI Official Full Name
15-lipoxygenase, partial
NCBI Official Synonym Full Names
arachidonate 15-lipoxygenase
NCBI Protein Information
arachidonate 15-lipoxygenase
UniProt Protein Name
Arachidonate 15-lipoxygenase
UniProt Synonym Protein Names
12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type (EC:1.13.11.31
UniProt Synonym Gene Names
UniProt Comments for 15-LO/LOX
ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family.
Protein type: EC 1.13.11.31; EC 1.13.11.33; Lipid Metabolism - arachidonic acid; Lipid Metabolism - linoleic acid; Motility/polarity/chemotaxis; Oxidoreductase
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: cytosol; extrinsic to internal side of plasma membrane; lipid particle; membrane; plasma membrane
Molecular Function: arachidonate 12-lipoxygenase activity; arachidonate 15-lipoxygenase activity; iron ion binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding
Biological Process: apoptotic cell clearance; arachidonic acid metabolic process; bone mineralization; hepoxilin biosynthetic process; inflammatory response; leukotriene metabolic process; lipoxygenase pathway; negative regulation of adaptive immune response; ossification; phosphatidylethanolamine biosynthetic process; positive regulation of actin filament polymerization; wound healing
Research Articles on 15-LO/LOX
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Products associated with 15-LO/LOX elisa kit
Pathways associated with 15-LO/LOX elisa kit
Diseases associated with 15-LO/LOX elisa kit
Organs/Tissues associated with 15-LO/LOX elisa kit
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