NP_032337.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,597 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 2B
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 2B
NCBI Protein Information
5-hydroxytryptamine receptor 2B; 5-HT-2B; 5-HT-2F; NP75 protein; serotonin receptor 2B
UniProt Protein Name
5-hydroxytryptamine receptor 2B
UniProt Synonym Protein Names
5-HT-2F; NP75 protein; Serotonin receptor 2B
UniProt Synonym Gene Names
UniProt Entry Name
5HT2B_MOUSE
UniProt Comments for HTR2B
5-HT(2B): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass
Cellular Component: neuron projection; membrane; integral to plasma membrane; cytoplasm; integral to membrane; plasma membrane; synapse; intracellular; cytosol; cell junction
Molecular Function: G-protein coupled receptor activity; signal transducer activity; serotonin binding; serotonin receptor activity; G-protein alpha-subunit binding; drug binding; GTPase activator activity
Biological Process: heart morphogenesis; negative regulation of autophagy; cGMP biosynthetic process; phosphoinositide 3-kinase cascade; intestine smooth muscle contraction; heart development; behavior; signal transduction; positive regulation of MAP kinase activity; smooth muscle contraction; positive regulation of cell proliferation; protein kinase C activation; neural crest cell differentiation; embryonic morphogenesis; neural crest cell migration; serotonin receptor signaling pathway; regulation of behavior; positive regulation of cytokine production; response to drug; vasoconstriction; serotonin receptor, phospholipase C activating pathway; positive regulation of nitric-oxide synthase activity; calcium-mediated signaling; positive regulation of phosphatidylinositol biosynthetic process; cellular calcium ion homeostasis; G-protein coupled receptor protein signaling pathway; G-protein coupled receptor internalization; phospholipase C activation; release of sequestered calcium ion into cytosol; positive regulation of cell division; positive regulation of endothelial cell proliferation; phosphorylation; positive regulation of GTPase activity; negative regulation of apoptosis; positive regulation of cytokine secretion
Research Articles on HTR2B
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Pathways associated with HTR2B elisa kit
Diseases associated with HTR2B elisa kit
Organs/Tissues associated with HTR2B elisa kit
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