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PTS elisa kit :: Mouse 6-pyruvoyltetrahydropterin synthase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9327458 PTS elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

6-pyruvoyltetrahydropterin synthase (PTS), ELISA Kit

 Also Known As   

Mouse 6-pyruvoyl tetrahydrobiopterin synthase, PTS ELISA Kit

 Product Synonym Names    Mouse 6-pyruvoyl tetrahydrobiopterin synthase (PTS) ELISA kit; FLJ97081; PTPS; 6-pyruvoyl tetrahydrobiopterin synthase; PTP synthase; 6-pyruvoyltetrahydropterin synthase
 Product Gene Name   

PTS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q9R1Z7
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PTS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PTS purchase    MBS9327458 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 6-pyruvoyltetrahydropterin synthase (PTS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PTS. The ELISA analytical biochemical technique of the MBS9327458 kit is based on PTS antibody-PTS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PTS. It may not necessarily be applicable to this product.
 NCBI GI #    7110709
 NCBI GeneID    19286
 NCBI Accession #    NP_035350.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_011220.2 [Other Products]
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 UniProt Primary Accession #    Q9R1Z7 [Other Products]
 UniProt Secondary Accession #    Q3UIB6; Q9Z2N2 [Other Products]
 UniProt Related Accession #    Q9R1Z7 [Other Products]
 Molecular Weight    16,188 Da
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 NCBI Official Full Name    6-pyruvoyl tetrahydrobiopterin synthase
 NCBI Official Synonym Full Names    6-pyruvoyl-tetrahydropterin synthase
 NCBI Official Symbol    Pts [Similar Products]
 NCBI Official Synonym Symbols   
PTPS
[Similar Products]
 NCBI Protein Information    6-pyruvoyl tetrahydrobiopterin synthase; PTP synthase
 UniProt Protein Name    6-pyruvoyl tetrahydrobiopterin synthase
 Protein Family    6-pyruvoyl tetrahydrobiopterin synthase
 UniProt Gene Name    Pts [Similar Products]
 UniProt Synonym Gene Names    PTP synthase; PTPS [Similar Products]
 UniProt Entry Name    PTPS_MOUSE
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 UniProt Comments for PTS    PTS: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6- pyruvoyl tetrahydropterin. Defects in PTS are the cause of BH4-deficient hyperphenylalaninemia type A (HPABH4A); also called 6-pyruvoyl-tetrahydropterin synthase deficiency (PTS deficiency) or hyperphenylalaninemia tetrahydrobiopterin-deficient due to PTS deficiency. HPABH4A is an autosomal recessive disorder characterized by depletion of the neurotransmitters dopamine and serotonin, and clinically by severe neurological symptoms unresponsive to the classic phenylalanine-low diet. Belongs to the PTPS family.

Protein type: Lyase; EC 4.2.3.12; Cofactor and Vitamin Metabolism - folate biosynthesis; Mitochondrial

Cellular Component: mitochondrion; cytoplasm

Molecular Function: identical protein binding; protein binding; protein homodimerization activity; metal ion binding; lyase activity; 6-pyruvoyltetrahydropterin synthase activity

Biological Process: tetrahydrobiopterin biosynthetic process
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 Research Articles on PTS    1. biopterin contents in the brains of these knock-out mice were moderately decreased from postnatal day 0 (P0) and remained constant up to P21
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PTS elisa kitDiseases associated with PTS elisa kit
 Products by Pathway  Pathway Diagram
 Folate Biosynthesis Pathway antibodies  Folate Biosynthesis Pathway Diagram
 Folate Biosynthesis Pathway antibodies  Folate Biosynthesis Pathway Diagram
 Tetrahydrobiopterin Biosynthesis I Pathway antibodies  Tetrahydrobiopterin Biosynthesis I Pathway Diagram
 Tetrahydrobiopterin Biosynthesis II Pathway antibodies  Tetrahydrobiopterin Biosynthesis II Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1932 publications with PTS and Cardiovascular Diseases
 Neoplasms Antibodies  >1319 publications with PTS and Neoplasms
 Myocardial Ischemia Antibodies  >690 publications with PTS and Myocardial Ischemia
 Myocardial Infarction Antibodies  >432 publications with PTS and Myocardial Infarction
 Pain Antibodies  >432 publications with PTS and Pain
 Drug Toxicity Antibodies  >355 publications with PTS and Drug Toxicity
 Immune System Diseases Antibodies  >354 publications with PTS and Immune System Diseases
 Heart Failure Antibodies  >326 publications with PTS and Heart Failure
 Hypertension Antibodies  >314 publications with PTS and Hypertension
 Kidney Diseases Antibodies  >293 publications with PTS and Kidney Diseases
Organs/Tissues associated with PTS elisa kit
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >1170 publications with PTS and Heart
 Kidney Antibodies  >379 publications with PTS and Kidney
 Lung Antibodies  >368 publications with PTS and Lung
 Brain Antibodies  >309 publications with PTS and Brain
 Liver Antibodies  >258 publications with PTS and Liver
 Lymph Node Antibodies  >165 publications with PTS and Lymph Node
 Bone Marrow Antibodies  >162 publications with PTS and Bone Marrow
 Inner Ear Antibodies  >95 publications with PTS and Inner Ear
 Prostate Antibodies  >71 publications with PTS and Prostate
 Stomach Antibodies  >67 publications with PTS and Stomach
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