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| Product Name
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ATPase, H+ transporting, lysosomal V0 subunit a2 (ATP6V0A2), ELISA Kit
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| Also Known As
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Mouse V-type proton ATPase 116 kDa subunit a isoform 2, ATP6V0A2 ELISA Kit
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| Product Synonym Names
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Mouse V-type proton ATPase 116 kDa subunit a isoform 2 (ATP6V0A2) ELISA kit; A2; ARCL; ATP6A2; ATP6N1D; J6B7; RTF; STV1; TJ6; TJ6M; TJ6S; VPH1; WSS; A2V-ATPase; ATPase; H+ transporting; lysosomal V0 subunit A2; regeneration and tolerance factor; v-ATPase 116 kDa; v-type proton A; ATPase; H+ transporting; lysosomal V0 subunit a2
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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| Request for Current Manual Insert
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| 3D Structure
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ModBase 3D Structure for P15920
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| Species Reactivity
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Mouse
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| Preparation and Storage
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Store all reagents at 2-8 degree C
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| Product Note
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Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
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| Other Notes
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Small volumes of ATP6V0A2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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| Searchable Terms for ATP6V0A2 purchase
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MBS9343340 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ATPase, H+ transporting, lysosomal V0 subunit a2 (ATP6V0A2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ATP6V0A2. The ELISA analytical biochemical technique of the MBS9343340 kit is based on ATP6V0A2 antibody-ATP6V0A2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ATP6V0A2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ATP6V0A2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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| NCBI/Uniprot data below describe general gene information for ATP6V0A2. It may not necessarily be applicable to this product. |
| NCBI GI #
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83627707
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| NCBI GeneID
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21871
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| NCBI Accession #
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NP_035726.2
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[Other Products]
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| NCBI GenBank Nucleotide #
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NM_011596.5
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[Other Products]
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| UniProt Primary Accession #
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P15920
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[Other Products]
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| UniProt Secondary Accession #
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Q3U2X3; Q8VHU0; Q9JHJ2; A4FU82
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[Other Products]
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| UniProt Related Accession #
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P15920
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[Other Products]
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| Molecular Weight
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98,145 Da
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| NCBI Official Full Name
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V-type proton ATPase 116 kDa subunit a isoform 2
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| NCBI Official Synonym Full Names
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ATPase, H+ transporting, lysosomal V0 subunit A2
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| NCBI Official Symbol
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Atp6v0a2
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[Similar Products]
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| NCBI Official Synonym Symbols
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ISF; Tj6; J6B7; SHIF; Stv1; TJ6M; TJ6s; ATP6a2; Atp6n2; C76904; Atp6n1d; AI385560; AW489264; V-ATPase a2; 8430408C20Rik; V-ATPase 116 kDa
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[Similar Products]
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| NCBI Protein Information
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V-type proton ATPase 116 kDa subunit a isoform 2; T-cell expressing clone j6; immune suppressor factor J6B7; ATPase, H+ transporting, lysosomal V0 subunit a; vacuolar proton translocating ATPase 116 kDa subunit a; ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 2 (38kD)
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| UniProt Protein Name
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V-type proton ATPase 116 kDa subunit a isoform 2
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| UniProt Synonym Protein Names
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Immune suppressor factor J6B7; ISF; Lysosomal H(+)-transporting ATPase V0 subunit a2; ShIF; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2
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| Protein Family
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V-type proton ATPase
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| UniProt Gene Name
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Atp6v0a2
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[Similar Products]
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| UniProt Synonym Gene Names
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Atp6n1b; Tj6; V-ATPase 116 kDa isoform a2; ISF
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[Similar Products]
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| UniProt Entry Name
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VPP2_MOUSE
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| NCBI Summary for ATP6V0A2
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This gene encodes a subunit of vacuolar ATPase, a multimeric enzyme that localizes to intracellular vesicles and to the plasma membrane of specialized cells. The encoded protein is a component of the V(0) domain, which functions in proton translocation across membranes. Function of this gene is important in fetal-specific immune suppression during pregnancy. [provided by RefSeq, May 2013]
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| UniProt Comments for ATP6V0A2
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ATP6V0A2: Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. Defects in ATP6V0A2 are the cause of cutis laxa autosomal recessive type 2A (ARCL2A). An autosomal recessive disorder characterized by an excessive congenital skin wrinkling, a large fontanelle with delayed closure, a typical facial appearance with downslanting palpebral fissures, a general connective tissue weakness, and varying degrees of growth and developmental delay and neurological abnormalities. Some affected individuals develop seizures and mental deterioration later in life, whereas the skin phenotype tends to become milder with age. At the molecular level, an abnormal glycosylation of serum proteins is observed in many cases. Defects in ATP6V0A2 are a cause of wrinkly skin syndrome (WSS). WSS is rare autosomal recessive disorder characterized by wrinkling of the skin of the dorsum of the hands and feet, an increased number of palmar and plantar creases, wrinkled abdominal skin, multiple musculoskeletal abnormalities, microcephaly, growth failure and developmental delay. Belongs to the V-ATPase 116 kDa subunit family.
Protein type: Energy Metabolism - oxidative phosphorylation; Transporter, ion channel; Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, iron
Cellular Component: focal adhesion; membrane; lysosomal membrane; cytoplasm; integral to membrane; plasma membrane; acrosome; vacuolar proton-transporting V-type ATPase complex; endosome
Molecular Function: protein binding; hydrogen ion transmembrane transporter activity; hydrogen ion transporting ATPase activity, rotational mechanism; ATPase binding
Biological Process: vacuolar acidification; ATP synthesis coupled proton transport; proton transport; transport; ATP hydrolysis coupled proton transport; ion transport
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| Research Articles on ATP6V0A2
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1. Report Atp6v0a2 up-regulation/inflammatory response during preimplantation period of pregnancy may lead to successful pregnancy outcome.
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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| Pathways associated with ATP6V0A2 elisa kit | Diseases associated with ATP6V0A2 elisa kit |
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ELISA Kit 
