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ATP6V0A2 elisa kit :: Mouse ATPase, H+ transporting, lysosomal V0 subunit a2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9343340 ATP6V0A2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ATPase, H+ transporting, lysosomal V0 subunit a2 (ATP6V0A2), ELISA Kit

 Also Known As   

Mouse V-type proton ATPase 116 kDa subunit a isoform 2, ATP6V0A2 ELISA Kit

 Product Synonym Names    Mouse V-type proton ATPase 116 kDa subunit a isoform 2 (ATP6V0A2) ELISA kit; A2; ARCL; ATP6A2; ATP6N1D; J6B7; RTF; STV1; TJ6; TJ6M; TJ6S; VPH1; WSS; A2V-ATPase; ATPase; H+ transporting; lysosomal V0 subunit A2; regeneration and tolerance factor; v-ATPase 116 kDa; v-type proton A; ATPase; H+ transporting; lysosomal V0 subunit a2
 Product Gene Name   

ATP6V0A2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 3D Structure    ModBase 3D Structure for P15920
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of ATP6V0A2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ATP6V0A2 purchase    MBS9343340 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ATPase, H+ transporting, lysosomal V0 subunit a2 (ATP6V0A2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ATP6V0A2. The ELISA analytical biochemical technique of the MBS9343340 kit is based on ATP6V0A2 antibody-ATP6V0A2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ATP6V0A2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ATP6V0A2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ATP6V0A2. It may not necessarily be applicable to this product.
 NCBI GI #    83627707
 NCBI GeneID    21871
 NCBI Accession #    NP_035726.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_011596.5 [Other Products]
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 UniProt Primary Accession #    P15920 [Other Products]
 UniProt Secondary Accession #    Q3U2X3; Q8VHU0; Q9JHJ2; A4FU82 [Other Products]
 UniProt Related Accession #    P15920 [Other Products]
 Molecular Weight    98,145 Da
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 NCBI Official Full Name    V-type proton ATPase 116 kDa subunit a isoform 2
 NCBI Official Synonym Full Names    ATPase, H+ transporting, lysosomal V0 subunit A2
 NCBI Official Symbol    Atp6v0a2 [Similar Products]
 NCBI Official Synonym Symbols   
ISF; Tj6; J6B7; SHIF; Stv1; TJ6M; TJ6s; ATP6a2; Atp6n2; C76904; Atp6n1d; AI385560; AW489264; V-ATPase a2; 8430408C20Rik; V-ATPase 116 kDa
[Similar Products]
 NCBI Protein Information    V-type proton ATPase 116 kDa subunit a isoform 2; T-cell expressing clone j6; immune suppressor factor J6B7; ATPase, H+ transporting, lysosomal V0 subunit a; vacuolar proton translocating ATPase 116 kDa subunit a; ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 2 (38kD)
 UniProt Protein Name    V-type proton ATPase 116 kDa subunit a isoform 2
 UniProt Synonym Protein Names   
Immune suppressor factor J6B7; ISF; Lysosomal H(+)-transporting ATPase V0 subunit a2; ShIF; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2
 Protein Family    V-type proton ATPase
 UniProt Gene Name    Atp6v0a2 [Similar Products]
 UniProt Synonym Gene Names    Atp6n1b; Tj6; V-ATPase 116 kDa isoform a2; ISF [Similar Products]
 UniProt Entry Name    VPP2_MOUSE
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 NCBI Summary for ATP6V0A2    This gene encodes a subunit of vacuolar ATPase, a multimeric enzyme that localizes to intracellular vesicles and to the plasma membrane of specialized cells. The encoded protein is a component of the V(0) domain, which functions in proton translocation across membranes. Function of this gene is important in fetal-specific immune suppression during pregnancy. [provided by RefSeq, May 2013]
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 UniProt Comments for ATP6V0A2    ATP6V0A2: Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. Defects in ATP6V0A2 are the cause of cutis laxa autosomal recessive type 2A (ARCL2A). An autosomal recessive disorder characterized by an excessive congenital skin wrinkling, a large fontanelle with delayed closure, a typical facial appearance with downslanting palpebral fissures, a general connective tissue weakness, and varying degrees of growth and developmental delay and neurological abnormalities. Some affected individuals develop seizures and mental deterioration later in life, whereas the skin phenotype tends to become milder with age. At the molecular level, an abnormal glycosylation of serum proteins is observed in many cases. Defects in ATP6V0A2 are a cause of wrinkly skin syndrome (WSS). WSS is rare autosomal recessive disorder characterized by wrinkling of the skin of the dorsum of the hands and feet, an increased number of palmar and plantar creases, wrinkled abdominal skin, multiple musculoskeletal abnormalities, microcephaly, growth failure and developmental delay. Belongs to the V-ATPase 116 kDa subunit family.

Protein type: Energy Metabolism - oxidative phosphorylation; Transporter, ion channel; Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, iron

Cellular Component: focal adhesion; membrane; lysosomal membrane; cytoplasm; integral to membrane; plasma membrane; acrosome; vacuolar proton-transporting V-type ATPase complex; endosome

Molecular Function: protein binding; hydrogen ion transmembrane transporter activity; hydrogen ion transporting ATPase activity, rotational mechanism; ATPase binding

Biological Process: vacuolar acidification; ATP synthesis coupled proton transport; proton transport; transport; ATP hydrolysis coupled proton transport; ion transport
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 Research Articles on ATP6V0A2    1. Report Atp6v0a2 up-regulation/inflammatory response during preimplantation period of pregnancy may lead to successful pregnancy outcome.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ATP6V0A2 elisa kitDiseases associated with ATP6V0A2 elisa kit
 Products by Pathway  Pathway Diagram
 Collecting Duct Acid Secretion Pathway antibodies  Collecting Duct Acid Secretion Pathway Diagram
 Collecting Duct Acid Secretion Pathway antibodies  Collecting Duct Acid Secretion Pathway Diagram
 Insulin Receptor Recycling Pathway antibodies  Insulin Receptor Recycling Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Disease Name  Pubmed Publications
 Wrinkly skin syndrome Antibodies  >4 publications with ATP6V0A2 and Wrinkly skin syndrome
 Nervous System Diseases Antibodies  >3 publications with ATP6V0A2 and Nervous System Diseases
 Neoplasms Antibodies  >2 publications with ATP6V0A2 and Neoplasms
 Brain Diseases Antibodies  >2 publications with ATP6V0A2 and Brain Diseases
 Neurobehavioral Manifestations Antibodies  >1 publications with ATP6V0A2 and Neurobehavioral Manifestations
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