NP_114127.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
67,608 Da
NCBI Official Full Name
ATPase family AAA domain-containing protein 3B
NCBI Official Synonym Full Names
ATPase family, AAA domain containing 3B
NCBI Protein Information
ATPase family AAA domain-containing protein 3B; AAA-ATPase TOB3
UniProt Protein Name
ATPase family AAA domain-containing protein 3B
UniProt Synonym Protein Names
AAA-TOB3
UniProt Synonym Gene Names
UniProt Entry Name
ATD3B_HUMAN
NCBI Summary for ATAD3B
ATAD3A (MIM 612316) and ATAD3B are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008]
UniProt Comments for ATAD3B
ATAD3B: May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes. Belongs to the AAA ATPase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: mitochondrial inner membrane
Molecular Function: ATP binding
Research Articles on ATAD3B
Precautions
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Diseases associated with ATAD3B elisa kit
Organs/Tissues associated with ATAD3B elisa kit
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