NP_001276939.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
68,169 Da
NCBI Official Full Name
acetylcholinesterase
NCBI Official Synonym Full Names
acetylcholinesterase
NCBI Protein Information
acetylcholinesterase
UniProt Protein Name
Acetylcholinesterase
UniProt Synonym Gene Names
UniProt Entry Name
ACES_MOUSE
UniProt Comments for AChE
ACHE: Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. Belongs to the type-B carboxylesterase/lipase family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.1.7; Lipid Metabolism - glycerophospholipid; Hydrolase; Membrane protein, GPI anchor
Cellular Component: Golgi apparatus; extracellular space; neuron projection; cell surface; rough endoplasmic reticulum; endoplasmic reticulum lumen; dendrite; extracellular region; nuclear envelope; presynaptic membrane; postsynaptic membrane; membrane; cell soma; perinuclear region of cytoplasm; axon; cytoplasm; plasma membrane; basal lamina; synapse; cell junction; neuromuscular junction
Molecular Function: collagen binding; choline binding; protein binding; serine hydrolase activity; protein homodimerization activity; cholinesterase activity; protein self-association; hydrolase activity; laminin binding; acetylcholinesterase activity; acetylcholine binding
Biological Process: neurotransmitter catabolic process; acetylcholine metabolic process; acetylcholine catabolic process; positive regulation of dendrite morphogenesis; synaptogenesis; choline metabolic process; retina development in camera-type eye; receptor internalization; neurotransmitter receptor biosynthetic process; regulation of receptor recycling; positive regulation of axonogenesis; cell adhesion; protein tetramerization
Research Articles on AChE
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Pathways associated with AChE elisa kit
Diseases associated with AChE elisa kit
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