NP_000667.1
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NCBI GenBank Nucleotide #
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UniProt Related Accession #
Molecular Weight
36,333 Da
NCBI Official Full Name
adenosine receptor A2b
NCBI Official Synonym Full Names
adenosine A2b receptor
NCBI Official Synonym Symbols
NCBI Protein Information
adenosine receptor A2b
UniProt Protein Name
Adenosine receptor A2b
UniProt Entry Name
AA2BR_HUMAN
NCBI Summary for ADORA2B
This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
UniProt Comments for ADORA2B
ADORA2B: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR
Chromosomal Location of Human Ortholog: 17p12
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: adenosine receptor activity, G-protein coupled
Biological Process: relaxation of vascular smooth muscle; activation of MAPK activity; adenylate cyclase activation; positive regulation of interleukin-6 production; positive regulation of guanylate cyclase activity; positive regulation of mast cell degranulation; excretion; G-protein signaling, adenylate cyclase activating pathway; positive regulation of chemokine production; G-protein coupled receptor protein signaling pathway; positive regulation of chronic inflammatory response to non-antigenic stimulus; cellular response to extracellular stimulus; cellular defense response; JNK cascade; adenosine receptor signaling pathway
Research Articles on ADORA2B
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Products associated with ADORA2B elisa kit
Pathways associated with ADORA2B elisa kit
Diseases associated with ADORA2B elisa kit
Organs/Tissues associated with ADORA2B elisa kit
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