NP_001292998.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,366 Da
NCBI Official Full Name
adiponectin receptor protein 1
NCBI Official Synonym Full Names
adiponectin receptor 1
NCBI Official Synonym Symbols
Paqr1; ACDCR1; CGI-45; 2810031L11Rik [Similar Products]
NCBI Protein Information
adiponectin receptor protein 1
UniProt Protein Name
Adiponectin receptor protein 1
UniProt Entry Name
ADR1_MOUSE
NCBI Summary for Adipor1
This gene encodes a receptor for the fat-derived hormone adiponectin. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. Homozygous knockout mice for this gene exhibit elevated plasma glucose and insulin levels as well as impaired glucose tolerance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
UniProt Comments for Adipor1
ADIPOR1: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. Belongs to the ADIPOR family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: integral to membrane; intrinsic to plasma membrane; membrane; plasma membrane
Molecular Function: adiponectin binding; identical protein binding; metal ion binding; protein binding; protein heterodimerization activity; protein kinase binding; receptor activity
Biological Process: adiponectin-mediated signaling pathway; fatty acid metabolic process; fatty acid oxidation; G-protein coupled receptor protein signaling pathway; glucose homeostasis; hormone-mediated signaling; leptin-mediated signaling pathway; lipid metabolic process; negative regulation of cell growth; positive regulation of insulin receptor signaling pathway; positive regulation of JAK-STAT cascade; regulation of lipid metabolic process
Research Articles on Adipor1
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Products associated with Adipor1 elisa kit
Pathways associated with Adipor1 elisa kit
Diseases associated with Adipor1 elisa kit
Organs/Tissues associated with Adipor1 elisa kit
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