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ACTH elisa kit :: Mouse Adrenocorticotropic Hormone (ACTH) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2024580 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells  /  $245 +1 FREE 8GB USB
48-Strip-Wells  /  $425 +1 FREE 8GB USB
96-Strip-Wells  /  $565 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,275 +2 FREE 8GB USB
10x96-Strip-Wells  /  $4,100 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Adrenocorticotropic Hormone (ACTH), ELISA Kit

★Popular Item★
 Also Known As   

Adrenocorticotropic Hormone (ACTH) ELISA Kit

 Product Synonym Names    Corticotropin; Adrenocorticotropin
 Product Gene Name   

ACTH elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of ACTH. No significant cross-reactivity or interference between ACTH and analogues was observed.
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 Samples    mouse serum, plasma and other biological fluids
 Detection Range    1.6-1,000pg/mL
 Sensitivity    <0.7pg/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level ACTH were tested 20 times on one plate, respectively. Intra-Assay: CV<10%
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level ACTH were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
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 Preparation and Storage    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ACTH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ACTH purchase    MBS2024580 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Adrenocorticotropic Hormone (ACTH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.6-1,000pg/mL in biological research samples containing ACTH, with an estimated sensitivity of <0.7pg/mL. The ELISA analytical biochemical technique of the MBS2024580 kit is based on ACTH antibody-ACTH antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ACTH antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ACTH. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as mouse serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for ACTH elisa kit

   Intended Uses: The kit is a competitive inhibition enzyme immunoassay technique for the in vitro quantitative measurement of ACTH in mouse serum, plasma and other biological fluids.
 Product Categories/Family for ACTH elisa kit    Endocrinology; Hormone metabolism
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 Typical Testing Data/Standard Curve (for reference only) of ACTH elisa kit    ACTH elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2024580. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ACTH. It may not necessarily be applicable to this product.
 NCBI GI #    191659
 NCBI GeneID    18976
 NCBI Accession #    AAA37169.1 [Other Products]
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 UniProt Secondary Accession #    P01200; Q544U4 [Other Products]
 UniProt Related Accession #    P01193 [Other Products]
 Molecular Weight    26,707 Da
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 NCBI Official Full Name    adrenocorticotropic hormone, partial
 NCBI Official Synonym Full Names    pro-opiomelanocortin-alpha
 NCBI Official Symbol    Pomc [Similar Products]
 NCBI Official Synonym Symbols   
BE; Npp; ACTH; Clip; Pomc1; Pomc-1; Beta-LPH; alphaMSH; beta-MSH; Gamma-LPH; alpha-MSH; gamma-MSH
[Similar Products]
 NCBI Protein Information    pro-opiomelanocortin
 UniProt Protein Name    Pro-opiomelanocortin
 UniProt Synonym Protein Names   
Corticotropin-lipotropin
 UniProt Gene Name    Pomc [Similar Products]
 UniProt Synonym Gene Names    Pomc1; POMC; ACTH; CLIP [Similar Products]
 UniProt Entry Name    COLI_MOUSE
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 NCBI Summary for ACTH    This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing. Processing yields several biologically active peptides, which are involved in diverse cellular functions, such as energy homeostasis, steroidogenesis, and increased melanin production in melanocytes. In mouse deficiency of this gene is associated with obesity, defects in adrenal development, and altered pigmentation. A pseudogene of this gene is located on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
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 UniProt Comments for ACTH    POMC: ACTH stimulates the adrenal glands to release cortisol. Defects in POMC may be associated with susceptibility to obesity (OBESITY). It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. Defects in POMC are the cause of pro-opiomelanocortinin deficiency (POMCD). Affected individuals present early-onset obesity, adrenal insufficiency and red hair. Belongs to the POMC family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space; peroxisomal matrix; cytoplasm; extracellular region; secretory granule

Molecular Function: type 3 melanocortin receptor binding; G-protein-coupled receptor binding; type 4 melanocortin receptor binding; hormone activity; receptor binding

Biological Process: generation of precursor metabolites and energy; cell-cell signaling; neuropeptide signaling pathway; regulation of blood pressure; regulation of appetite; positive regulation of transcription from RNA polymerase II promoter; negative regulation of tumor necrosis factor production; signal transduction; glucose homeostasis; cellular pigmentation
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 Research Articles on ACTH    1. Data indicate that LIM-homeodomain transcription factor Islet 1 is necessary for hypothalamic proopiomelanocortin gene (Pomc) expression during embryogenesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ACTH elisa kitDiseases associated with ACTH elisa kit
 Products by Pathway  Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytochrome P450 - Arranged By Substrate Type Pathway antibodies  Cytochrome P450 - Arranged By Substrate Type Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway antibodies  Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway Diagram
 Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway antibodies  Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway Diagram
 Defective CYP11B2 Causes Corticosterone Methyloxidase 1 Deficiency (CMO-1 Deficiency) Pathway antibodies  Defective CYP11B2 Causes Corticosterone Methyloxidase 1 Deficiency (CMO-1 Deficiency) Pathway Diagram
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >4200 publications with ACTH and Immune System Diseases
 Cushing Syndrome Antibodies  >2893 publications with ACTH and Cushing Syndrome
 Mental Disorders Antibodies  >2663 publications with ACTH and Mental Disorders
 Obesity Antibodies  >1721 publications with ACTH and Obesity
 Infection Antibodies  >1014 publications with ACTH and Infection
 Kidney Diseases Antibodies  >1002 publications with ACTH and Kidney Diseases
 Gastrointestinal Diseases Antibodies  >942 publications with ACTH and Gastrointestinal Diseases
 Diabetes Mellitus Antibodies  >849 publications with ACTH and Diabetes Mellitus
 Necrosis Antibodies  >672 publications with ACTH and Necrosis
 Hemorrhage Antibodies  >670 publications with ACTH and Hemorrhage
Organs/Tissues associated with ACTH elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >18452 publications with ACTH and Brain
 Pituitary Gland Antibodies  >9007 publications with ACTH and Pituitary Gland
 Skin Antibodies  >1874 publications with ACTH and Skin
 Testis Antibodies  >554 publications with ACTH and Testis
 Embryonic Tissue Antibodies  >392 publications with ACTH and Embryonic Tissue
 Uncharacterized Tissue Antibodies  >2 publications with ACTH and Uncharacterized Tissue
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