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Snca elisa kit :: Mouse Alpha-synuclein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2884828
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $380 +1 FREE 8GB USB
96-Strip-Wells  /  $500 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,170 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,840 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Alpha-synuclein (Snca), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Alpha-synuclein ELISA Kit

 Product Synonym Names    Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP; Snca; Syn
 Product Gene Name   

Snca elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2884828 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for O55042
 Species Reactivity    Mouse
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 Assay Type    Sandwich
 Detection Range    78-5000 pg/mL
 Sensitivity    3.96 pg/mL
 Intra-Assay CV    <=8.3%
 Inter-Assay CV    <=10.0%
 Recovery    86%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Snca elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Snca purchase    MBS2884828 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Alpha-synuclein (Snca) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78-5000 pg/mL in biological research samples containing Snca, with an estimated sensitivity of 3.96 pg/mL. The ELISA analytical biochemical technique of the MBS2884828 kit is based on Snca antibody-Snca antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Snca antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Snca. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for Snca elisa kit

   Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of Snca elisa kit    Snca elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2884828. Click to request current manual
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NCBI/Uniprot data below describe general gene information for Snca. It may not necessarily be applicable to this product.
 NCBI GI #    109638747
 NCBI GeneID    20617
 NCBI Accession #    NP_001035916.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042451.2 [Other Products]
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 UniProt Primary Accession #    O55042 [Other Products]
 UniProt Secondary Accession #    Q3U130; Q9CXF8; Q9EQC3; Q9QUR3 [Other Products]
 UniProt Related Accession #    O55042 [Other Products]
 Molecular Weight    12,345 Da
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 NCBI Official Full Name    alpha-synuclein
 NCBI Official Synonym Full Names    synuclein, alpha
 NCBI Official Symbol    Snca [Similar Products]
 NCBI Official Synonym Symbols   
NACP; alphaSYN
[Similar Products]
 NCBI Protein Information    alpha-synuclein
 UniProt Protein Name    Alpha-synuclein
 UniProt Synonym Protein Names   
Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP
 Protein Family    Alpha-synuclein
 UniProt Gene Name    Snca [Similar Products]
 UniProt Synonym Gene Names    Syn; NACP [Similar Products]
 UniProt Entry Name    SYUA_MOUSE
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 UniProt Comments for Snca    SNCA: a member of the synuclein family. Abundantly expressed in the brain. Inhibits phospholipase D2 selectively. May integrate presynaptic signaling and membrane trafficking. Implicated in the pathogenesis of Parkinson's disease. A major component of amyloid plaques in the brains of patients with Alzheimer's disease. Two alternatively spliced isoforms transcripts have been identified.

Protein type: Adaptor/scaffold

Cellular Component: actin cytoskeleton; axon; cell cortex; cell junction; cytoplasm; cytoplasmic vesicle membrane; cytoskeleton; cytosol; extracellular region; extracellular space; fibril; Golgi apparatus; growth cone; inclusion body; intracellular membrane-bound organelle; membrane; mitochondrion; nerve terminal; nuclear outer membrane; nucleus; perinuclear region of cytoplasm; plasma membrane; platelet alpha granule membrane; ribosome; rough endoplasmic reticulum; synapse; synaptic vesicle; terminal button

Molecular Function: alpha-tubulin binding; arachidonic acid binding; beta-tubulin binding; calcium ion binding; caspase inhibitor activity; copper ion binding; dynein binding; enzyme binding; ferrous iron binding; histone binding; identical protein binding; kinesin binding; magnesium ion binding; metal ion binding; microtubule binding; oxidoreductase activity; phospholipase binding; phospholipid binding; phosphoprotein binding; protein binding; protein domain specific binding; protein N-terminus binding; tau protein binding; zinc ion binding

Biological Process: adult locomotory behavior; behavioral response to cocaine; caspase activation; dopamine biosynthetic process; dopamine metabolic process; fatty acid metabolic process; microglial cell activation; mitochondrial membrane organization and biogenesis; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of dopamine metabolic process; negative regulation of dopamine uptake; negative regulation of exocytosis; negative regulation of histone acetylation; negative regulation of microtubule polymerization; negative regulation of monooxygenase activity; negative regulation of neuron apoptosis; negative regulation of norepinephrine uptake; negative regulation of protein amino acid phosphorylation; negative regulation of serotonin uptake; negative regulation of transporter activity; neutral lipid metabolic process; organelle ATP synthesis coupled electron transport; phospholipid metabolic process; positive regulation of endocytosis; positive regulation of neurotransmitter secretion; positive regulation of peptidyl-serine phosphorylation; positive regulation of receptor recycling; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of synaptic transmission; protein destabilization; receptor internalization; regulation of acyl-CoA biosynthetic process; regulation of dopamine secretion; regulation of excitatory postsynaptic membrane potential; regulation of glutamate secretion; regulation of locomotion; regulation of long-term neuronal synaptic plasticity; regulation of macrophage activation; regulation of neuron apoptosis; regulation of neuronal synaptic plasticity; regulation of neurotransmitter secretion; response to drug; response to iron(II) ion; response to lipopolysaccharide; response to magnesium ion; synapse organization and biogenesis; synaptic transmission; synaptic transmission, dopaminergic; synaptic vesicle endocytosis; synaptic vesicle transport
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 Research Articles on Snca    1. Activation of MyD88-dependent TLR1/2 signaling by misfolded alpha-synuclein, a protein linked to neurodegenerative disorders.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Snca elisa kitPathways associated with Snca elisa kit
 Reference Product  PubMed Publications
 Park2 elisa kit  >1029 publications with Snca and Park2
 Lrrk2 elisa kit  >150 publications with Snca and Lrrk2
 Sncaip elisa kit  >33 publications with Snca and Sncaip
 Slc6a3 elisa kit  >27 publications with Snca and Slc6a3
 App elisa kit  >19 publications with Snca and App
 Fyn elisa kit  >2 publications with Snca and Fyn
 B2m elisa kit  >1 publications with Snca and B2m
 Itm2b elisa kit  >1 publications with Snca and Itm2b
 Abl1 elisa kit  >1 publications with Snca and Abl1
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Parkinson's Disease Pathway antibodies  Parkinson's Disease Pathway Diagram
Diseases associated with Snca elisa kitOrgans/Tissues associated with Snca elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1271 publications with Snca and Nervous System Diseases
 Brain Diseases Antibodies  >1244 publications with Snca and Brain Diseases
 Neurodegenerative Diseases Antibodies  >1226 publications with Snca and Neurodegenerative Diseases
 Movement Disorders Antibodies  >1103 publications with Snca and Movement Disorders
 Parkinsonian Disorders Antibodies  >1019 publications with Snca and Parkinsonian Disorders
 Parkinson Disease Antibodies  >965 publications with Snca and Parkinson Disease
 Lewy Body Disease Antibodies  >301 publications with Snca and Lewy Body Disease
 Disease Models, Animal Antibodies  >174 publications with Snca and Disease Models, Animal
 Nerve Degeneration Antibodies  >174 publications with Snca and Nerve Degeneration
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >886 publications with Snca and Brain
 Embryonic Tissue Antibodies  >28 publications with Snca and Embryonic Tissue
 Eye Antibodies  >12 publications with Snca and Eye
 Liver Antibodies  >11 publications with Snca and Liver
 Bone Antibodies  >8 publications with Snca and Bone
 Skin Antibodies  >8 publications with Snca and Skin
 Lung Antibodies  >7 publications with Snca and Lung
 Sympathetic Ganglion Antibodies  >6 publications with Snca and Sympathetic Ganglion
 Olfactory Mucosa Antibodies  >2 publications with Snca and Olfactory Mucosa
 Prostate Antibodies  >2 publications with Snca and Prostate
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