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ALMS1 elisa kit :: Mouse Alstrom syndrome protein 1 (ALMS1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7243224 ALMS1 elisa kit
Unit / Price
48-Strip-Wells  /  $455 +1 FREE 8GB USB
96-Strip-Wells  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Alstrom syndrome protein 1 (ALMS1), ELISA Kit

 Also Known As   

Mouse Alstrom syndrome protein 1 (ALMS1) ELISA Kit

 Product Gene Name   

ALMS1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    606844
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 Species Reactivity    Mouse
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    100-2500pg/mL
 Sensitivity    1.0pg/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ALMS1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ALMS1 purchase    MBS7243224 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Alstrom syndrome protein 1 (ALMS1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 100-2500pg/mL in biological research samples containing ALMS1, with an estimated sensitivity of 1.0pg/mL. The ELISA analytical biochemical technique of the MBS7243224 kit is based on ALMS1 antibody-ALMS1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ALMS1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ALMS1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for ALMS1 elisa kit    Immunology
NCBI/Uniprot data below describe general gene information for ALMS1. It may not necessarily be applicable to this product.
 NCBI GI #    110349786
 NCBI GeneID    7840
 NCBI Accession #    NP_055935.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_015120.4 [Other Products]
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 UniProt Secondary Accession #    Q53S05; Q580Q8; Q86VP9; Q9Y4G4 [Other Products]
 UniProt Related Accession #    Q8TCU4 [Other Products]
 Molecular Weight    425,137 Da
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 NCBI Official Full Name    Alstrom syndrome protein 1
 NCBI Official Synonym Full Names    Alstrom syndrome 1
 NCBI Official Symbol    ALMS1 [Similar Products]
 NCBI Official Synonym Symbols   
ALSS
[Similar Products]
 NCBI Protein Information    Alstrom syndrome protein 1
 UniProt Protein Name    Alstrom syndrome protein 1
 Protein Family    Alstrom syndrome protein
 UniProt Gene Name    ALMS1 [Similar Products]
 UniProt Synonym Gene Names    KIAA0328 [Similar Products]
 UniProt Entry Name    ALMS1_HUMAN
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 NCBI Summary for ALMS1    This gene encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations in this gene cause Alstrom syndrome. There is a pseudogene for this gene located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined. [provided by RefSeq, Apr 2014]
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 UniProt Comments for ALMS1    ALMS1: Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells. Defects in ALMS1 are the cause of Alstrom syndrome (ALMS). Alstrom syndrome is a rare autosomal recessive disorder characterized by progressive cone-rod retinal dystrophy, neurosensory hearing loss, early childhood obesity and type 2 diabetes mellitus. Dilated cardiomyopathy, acanthosis nigricans, male hypogonadism, hypothyroidism, developmental delay and hepatic dysfunction can also be associated with the syndrome. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 2p13

Cellular Component: nucleoplasm; centriole; spindle pole; centrosome; cytoplasm; cytosol; nucleus; cilium

Molecular Function: protein binding

Biological Process: organelle organization and biogenesis; regulation of stress fiber formation; mitotic cell cycle; endosome transport; G2/M transition of mitotic cell cycle

Disease: Alstrom Syndrome
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 Research Articles on ALMS1    1. Data indicate that representative single-nucleotide polymorphisms of the Alstrom syndrome 1 gene (ALMS1) promoter region were significantly associated with early-onset myocardial infarction (MI) in both Japanese and Korean populations.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ALMS1 elisa kitPathways associated with ALMS1 elisa kit
 Reference Product  PubMed Publications
 SDCCAG8 elisa kit  >1 publications with ALMS1 and SDCCAG8
 OFD1 elisa kit  >1 publications with ALMS1 and OFD1
 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Centrosome Maturation Pathway antibodies  Centrosome Maturation Pathway Diagram
 G2/M Transition Pathway antibodies  G2/M Transition Pathway Diagram
 Loss Of Nlp From Mitotic Centrosomes Pathway antibodies  Loss Of Nlp From Mitotic Centrosomes Pathway Diagram
 Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway antibodies  Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway Diagram
 Mitotic G2-G2/M Phases Pathway antibodies  Mitotic G2-G2/M Phases Pathway Diagram
 Recruitment Of Mitotic Centrosome Proteins And Complexes Pathway antibodies  Recruitment Of Mitotic Centrosome Proteins And Complexes Pathway Diagram
 Regulation Of PLK1 Activity At G2/M Transition Pathway antibodies  Regulation Of PLK1 Activity At G2/M Transition Pathway Diagram
Diseases associated with ALMS1 elisa kitOrgans/Tissues associated with ALMS1 elisa kit
 Disease Name  Pubmed Publications
 Alstrom Syndrome Antibodies  >71 publications with ALMS1 and Alstrom Syndrome
 Congenital Abnormalities Antibodies  >42 publications with ALMS1 and Congenital Abnormalities
 Nervous System Malformations Antibodies  >30 publications with ALMS1 and Nervous System Malformations
 Cardiomyopathy, Dilated Antibodies  >24 publications with ALMS1 and Cardiomyopathy, Dilated
 Fibrosis Antibodies  >15 publications with ALMS1 and Fibrosis
 Liver Diseases Antibodies  >13 publications with ALMS1 and Liver Diseases
 Hypertension Antibodies  >7 publications with ALMS1 and Hypertension
 Fatty Liver Antibodies  >7 publications with ALMS1 and Fatty Liver
 Inflammation Antibodies  >6 publications with ALMS1 and Inflammation
 Hepatomegaly Antibodies  >3 publications with ALMS1 and Hepatomegaly
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >17 publications with ALMS1 and Liver
 Kidney Antibodies  >9 publications with ALMS1 and Kidney
 Heart Antibodies  >9 publications with ALMS1 and Heart
 Eye Antibodies  >7 publications with ALMS1 and Eye
 Adipose Tissue Antibodies  >7 publications with ALMS1 and Adipose Tissue
 Connective Tissue Antibodies  >5 publications with ALMS1 and Connective Tissue
 Lung Antibodies  >4 publications with ALMS1 and Lung
 Brain Antibodies  >4 publications with ALMS1 and Brain
 Bone Antibodies  >3 publications with ALMS1 and Bone
 Thyroid Antibodies  >3 publications with ALMS1 and Thyroid
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