NP_031466.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75,390 Da
NCBI Official Full Name
arachidonate 12-lipoxygenase, 12S-type
NCBI Official Synonym Full Names
arachidonate 12-lipoxygenase
NCBI Protein Information
arachidonate 12-lipoxygenase, 12S-type
UniProt Protein Name
Arachidonate 12-lipoxygenase, 12S-type
UniProt Synonym Protein Names
Lipoxin synthase 12-LO (EC:3.3.2.-); Platelet-type lipoxygenase 12; P-12LO
UniProt Synonym Gene Names
UniProt Entry Name
LOX12_MOUSE
UniProt Comments for Alox12
ALOX12: Oxygenase and 14,15-leukotriene A4 synthase activity. Belongs to the lipoxygenase family.
Protein type: Apoptosis; EC 1.13.11.31; Oxidoreductase; Lipid Metabolism - arachidonic acid
Cellular Component: cytoplasm; cytosol; membrane; sarcolemma
Molecular Function: arachidonate 12-lipoxygenase activity; dioxygenase activity; epoxide hydrolase A activity; epoxide hydrolase B activity; hydrolase activity; iron ion binding; juvenile hormone epoxide hydrolase activity; lipoxygenase activity; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; phenanthrene-1,2-epoxide hydrolase activity; phenanthrene-3,4-epoxide hydrolase activity; phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity; phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity; phenanthrene-9,10-epoxide hydrolase activity; phenanthrene-epoxide hydrolase activity
Biological Process: arachidonic acid metabolic process; cell motility; fatty acid metabolic process; fatty acid oxidation; hepoxilin biosynthetic process; lipid metabolic process; lipoxygenase pathway; negative regulation of apoptosis; positive regulation of angiogenesis; positive regulation of apoptosis; positive regulation of caspase activity; positive regulation of cell adhesion; positive regulation of cell growth; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of endothelial cell differentiation; positive regulation of mitochondrial depolarization; positive regulation of smooth muscle cell proliferation; positive regulation of vasodilation
Research Articles on Alox12
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Products associated with Alox12 elisa kit
Pathways associated with Alox12 elisa kit
Diseases associated with Alox12 elisa kit
Organs/Tissues associated with Alox12 elisa kit
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