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BMP-2 elisa kit :: Mouse BMP-2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2514138 (SPECIAL PROMOTIONAL PRICING for a limited time)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $310 +1 FREE 8GB USB
96-Strip-Wells  /  $355 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,435 +1 FREE 8GB USB
10x96-Strip-Wells  /  $2,805 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BMP-2, ELISA Kit

★Popular Item★
 Also Known As   

Mouse BMP-2 (Bone Morphogenetic Protein 2) ELISA Kit

 Product Gene Name   

BMP-2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    112261
 3D Structure    ModBase 3D Structure for P12643
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 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse BMP-2. No significant cross-reactivity or interference between Mouse BMP-2 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Mouse BMP-2 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    62.5-4000pg/mL
 Sensitivity    Min: 37.5pg/mL; Max: 4000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BMP-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMP-2 purchase    MBS2514138 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the BMP-2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5-4000pg/mL in biological research samples containing BMP-2, with an estimated sensitivity of Min: 37.5pg/mL; Max: 4000pg/mL. The ELISA analytical biochemical technique of the MBS2514138 kit is based on BMP-2 antibody-BMP-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for BMP-2 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of BMP-2 in Mouse serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse BMP-2. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Mouse BMP-2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse BMP-2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse BMP-2. You can calculate the concentration of Mouse BMP-2 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of BMP-2 elisa kit    BMP-2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2514138. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BMP-2. It may not necessarily be applicable to this product.
 NCBI GI #    6649952
 NCBI GeneID    650
 NCBI Accession #    AAF21646.1 [Other Products]
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 UniProt Primary Accession #    P12643 [Other Products]
 UniProt Related Accession #    P12643 [Other Products]
 Molecular Weight    44,702 Da
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 NCBI Official Full Name    bone morphogenetic protein 2
 NCBI Official Synonym Full Names    bone morphogenetic protein 2
 NCBI Official Symbol    BMP2 [Similar Products]
 NCBI Official Synonym Symbols   
BDA2; BMP2A
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 2; BMP-2A; bone morphogenetic protein 2A
 UniProt Protein Name    Bone morphogenetic protein 2
 UniProt Synonym Protein Names   
Bone morphogenetic protein 2A; BMP-2A
 Protein Family    BMP-2-inducible protein kinase
 UniProt Gene Name    BMP2 [Similar Products]
 UniProt Synonym Gene Names    BMP2A; BMP-2; BMP-2A [Similar Products]
 UniProt Entry Name    BMP2_HUMAN
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 NCBI Summary for BMP-2    The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BMP-2    Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
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 Research Articles on BMP-2    1. the released BMP-2 directs osteogenic differentiation in vitro and in vivo.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BMP-2 elisa kitPathways associated with BMP-2 elisa kit
 Reference Product  PubMed Publications
 BMPR2 elisa kit  >207 publications with BMP-2 and BMPR2
 BMPR1A elisa kit  >180 publications with BMP-2 and BMPR1A
 SMAD4 elisa kit  >95 publications with BMP-2 and SMAD4
 BMPR1B elisa kit  >60 publications with BMP-2 and BMPR1B
 SMAD7 elisa kit  >33 publications with BMP-2 and SMAD7
 NOG elisa kit  >11 publications with BMP-2 and NOG
 ACVR2B elisa kit  >9 publications with BMP-2 and ACVR2B
 GREM2 elisa kit  >8 publications with BMP-2 and GREM2
 CHRD elisa kit  >3 publications with BMP-2 and CHRD
 SOSTDC1 elisa kit  >2 publications with BMP-2 and SOSTDC1
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signalling And Regulation Pathway antibodies  BMP Signalling And Regulation Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
Diseases associated with BMP-2 elisa kitOrgans/Tissues associated with BMP-2 elisa kit
 Disease Name  Pubmed Publications
 Bone Diseases Antibodies  >569 publications with BMP-2 and Bone Diseases
 Necrosis Antibodies  >112 publications with BMP-2 and Necrosis
 Inflammation Antibodies  >93 publications with BMP-2 and Inflammation
 Pain Antibodies  >46 publications with BMP-2 and Pain
 Hypertrophy Antibodies  >45 publications with BMP-2 and Hypertrophy
 Hypertension Antibodies  >44 publications with BMP-2 and Hypertension
 Fibrosis Antibodies  >34 publications with BMP-2 and Fibrosis
 Adenocarcinoma Antibodies  >32 publications with BMP-2 and Adenocarcinoma
 Kidney Diseases Antibodies  >32 publications with BMP-2 and Kidney Diseases
 Breast Neoplasms Antibodies  >32 publications with BMP-2 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >4191 publications with BMP-2 and Bone
 Connective Tissue Antibodies  >647 publications with BMP-2 and Connective Tissue
 Embryonic Tissue Antibodies  >456 publications with BMP-2 and Embryonic Tissue
 Heart Antibodies  >192 publications with BMP-2 and Heart
 Brain Antibodies  >163 publications with BMP-2 and Brain
 Kidney Antibodies  >94 publications with BMP-2 and Kidney
 Lung Antibodies  >83 publications with BMP-2 and Lung
 Liver Antibodies  >70 publications with BMP-2 and Liver
 Eye Antibodies  >63 publications with BMP-2 and Eye
 Uterus Antibodies  >30 publications with BMP-2 and Uterus
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